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This study introduces a pioneering machine learning (ML)-based approach for predicting the impact of nanoparticle (NP) carriers on the functionality of attached small biomolecules. It was hypothesised that NP interactions induce measurable…

Quantitative Methods · Quantitative Biology 2026-03-23 Mariya L. Ivanova , Michael Nicholls , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

The article introduces a concept for a time- and cost-effective methodological framework leveraging machine learning (ML) models for both early-stage drug development and clinical trial support. The rationale for this approach is the…

Quantitative Methods · Quantitative Biology 2025-12-04 Mariya L. Ivanova , Michael Nicholls , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

The study expands the application of scikit-learn-based machine learning (ML) to the prediction of small biomolecule functionalities based on Carbon 13 isotope (13C) NMR spectroscopy data derived from Simplified Molecular Input Line Entry…

Quantitative Methods · Quantitative Biology 2025-07-24 Mariya L. Ivanova , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

This paper presents the development of machine learning (ML) models to predict hypoxemia severity during emergency triage, especially in Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) events, using physiological data…

Machine Learning · Computer Science 2024-11-01 Santino Nanini , Mariem Abid , Yassir Mamouni , Arnaud Wiedemann , Philippe Jouvet , Stephane Bourassa

The article proposes a conceptual approach for evaluating the impact of engineered nanoparticles (NPs) on the functionality of small biomolecules. The developed machine learning (ML) model is based on in-silico 13C NMR spectroscopy chemical…

Other Quantitative Biology · Quantitative Biology 2026-03-23 Mariya L Ivanova , Michael Nichols , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

A great deal of effort has been devoted to discovering a particular genetic disorder, but its classification across a broad spectrum of disorder classes and types remains elusive. Early diagnosis of genetic disorders enables timely…

Artificial Intelligence · Computer Science 2024-12-04 Abu Bakar Siddik , Faisal R. Badal , Afroza Islam

Student's mental health problems have been explored previously in higher education literature in various contexts including empirical work involving quantitative and qualitative methods. Nevertheless, comparatively few research could be…

Applications · Statistics 2022-03-01 Prathamesh Muzumdar , Ganga Prasad Basyal , Piyush Vyas

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

This study reveals the important role of prevention care and medication adherence in reducing hospitalizations. By using a structured dataset of 1,171 patients, four machine learning models Logistic Regression, Gradient Boosting, Random…

Machine Learning · Computer Science 2025-04-11 Yixin Zhang , Yisong Chen

Many recent studies use machine learning to predict a small number of ICD-9-CM codes. In practice, on the other hand, physicians have to consider a broader range of diagnoses. This study aims to put these previously incongruent evaluation…

Applications · Statistics 2020-06-25 Gil Alon , Elizabeth Chen , Guergana Savova , Carsten Eickhoff

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury

Machine Learning applications have brought new insights into a secondary analysis of medical data. Machine Learning helps to develop new drugs, define populations susceptible to certain illnesses, identify predictors of many common…

Machine Learning · Computer Science 2020-12-29 YuanZheng Hu , Marina Sokolova

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

Machine Learning · Computer Science 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Molecular Networks · Quantitative Biology 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya

Meta-learning offers a principled framework leveraging \emph{task-invariant} priors from related tasks, with which \emph{task-specific} models can be fine-tuned on downstream tasks, even with limited data records. Gradient-based…

Machine Learning · Computer Science 2026-04-16 Yilang Zhang , Abraham Jaeger Mountain , Bingcong Li , Georgios B. Giannakis

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Trusting the accuracy of data inputted on online platforms can be difficult due to the possibility of malicious websites gathering information for unlawful reasons. Analyzing each website individually becomes challenging with the presence…

Cryptography and Security · Computer Science 2024-06-18 Mohammad Maftoun , Nima Shadkam , Seyedeh Somayeh Salehi Komamardakhi , Zulkefli Mansor , Javad Hassannataj Joloudari

A new attention-based model for the gradient boosting machine (GBM) called AGBoost (the attention-based gradient boosting) is proposed for solving regression problems. The main idea behind the proposed AGBoost model is to assign attention…

Machine Learning · Computer Science 2022-07-13 Andrei Konstantinov , Lev Utkin , Stanislav Kirpichenko

INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…

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