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Quantifying stochastic processes is essential to understand many natural phenomena, particularly in biology, including cell-fate decision in developmental processes as well as genesis and progression of cancers. While various attempts have…

Statistical Mechanics · Physics 2017-06-28 Ying Tang , Ruoshi Yuan , Gaowei Wang , Xiaomei Zhu , Ping Ao

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

Neurons and Cognition · Quantitative Biology 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

We consider a damped $\beta$-Fermi-Pasta-Ulam chain, driven at one boundary subjected to stochastic noise. It is shown that, for a fixed driving amplitude and frequency, increasing the noise intensity, the system's energy resonantly…

Pattern Formation and Solitons · Physics 2009-11-13 George Miloshevich , Ramaz Khomeriki , Stefano Ruffo

Mathematical models of gene regulatory networks are widely used to study cell fate changes and transcriptional regulation. When designing such models, it is important to accurately account for sources of stochasticity. However, doing so can…

Molecular Networks · Quantitative Biology 2025-03-21 Jochen Kursawe , Antoine Moneyron , Tobias Galla

We study individual-based dynamics in finite populations, subject to randomly switching environmental conditions. These are inspired by models in which genes transition between on and off states, regulating underlying protein dynamics.…

Statistical Mechanics · Physics 2016-05-18 Peter G. Hufton , Yen Ting Lin , Tobias Galla , Alan J. McKane

The objectives and contributions of this paper are mathematical and numerical analyses of a stochastic control problem of bounded population dynamics under ambiguity, an important but not well-studied problem, focusing on the optimality…

Optimization and Control · Mathematics 2020-07-06 H. Yoshioka , M. Tsujimura

Regulatory networks describe the interactions between molecular or cellular regulators, like transcription factors and genes in gene regulatory networks, kinases and their receptors in signalling networks, or neurons in neural networks. A…

Molecular Networks · Quantitative Biology 2022-12-29 Niklas Bonacker , Johannes Berg

We study the dynamics of a simple adaptive system in the presence of noise and periodic damping. The system is composed by two paths connecting a source and a sink, the dynamics is governed by equations that usually describe food search of…

Statistical Mechanics · Physics 2021-12-23 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

Response lags are generic to almost any physical system and often play a crucial role in the feedback loops present in artificial nanodevices and biological molecular machines. In this paper, we perform a comprehensive study of small…

Statistical Mechanics · Physics 2015-06-23 M. L. Rosinberg , T. Munakata , G. Tarjus

Simple dynamical systems -- with a small number of degrees of freedom -- can behave in a complex manner due to the presence of chaos. Such systems are most often (idealized) limiting cases of more realistic situations. Isolating a small…

Chaotic Dynamics · Physics 2015-04-17 Temple He , Salman Habib

The phenomenon of Stochastic Resonance (SR) is reported in a completely noise-free situation, with the role of thermal noise being taken by low-dimensional chaos. A one-dimensional, piecewise linear map and a pair of coupled…

chao-dyn · Physics 2009-10-31 Sitabhra Sinha

We consider a stochastic population model where the intrinsic or demographic noise causes cycling between states before the population eventually goes extinct. A master equation approach coupled with a WKB (Wentzel-Kramers-Brillouin)…

Populations and Evolution · Quantitative Biology 2014-12-16 Garrett Nieddu , Lora Billings , Eric Forgoston

The past decade has seen a revived interest in the unavoidable or intrinsic noise in biochemical and genetic networks arising from the finite copy number of the participating species. That is, rather than modeling regulatory networks in…

Molecular Networks · Quantitative Biology 2015-03-17 Aleksandra M. Walczak , Andrew Mugler , Chris H. WIggins

We study the impact of stochastic perturbations to deterministic dynamical systems using the formalism of the Ruelle response theory and explore how stochastic noise can be used to explore the properties of the underlying deterministic…

Statistical Mechanics · Physics 2015-05-27 Valerio Lucarini

The most frequently used in physical application diffusive (based on the Fokker-Planck equation) model leans upon the assumption of small jumps of a macroscopic variable for each given realization of the stochastic process. This imposes…

Statistical Mechanics · Physics 2007-05-23 Serge Shpyrko , V. V. Ryazanov

We study the stochastic dynamics of a system of interacting species in a stochastic environment by means of a continuous-time Markov chain with transition rates depending on the state of the environment. Models of gene regulation in systems…

Dynamical Systems · Mathematics 2019-12-03 Daniele Cappelletti , Abhishek Pal Majumder , Carsten Wiuf

Quantifying energy flows at nanometer scales promises to guide future research in a variety of disciplines, from microscopic control and manipulation, to autonomously operating molecular machines. A general understanding of the…

Statistical Mechanics · Physics 2018-11-26 Steven J. Large , Raphaël Chetrite , David A. Sivak

We analytically determine the correlation functions of the stochastic response of a generic mapping system driven by colored noise. We also address the issue of noise cascading in coupled-element systems, particularly in a uni-directionally…

chao-dyn · Physics 2007-05-23 Rue-Ron Hsu , Jyh-Long Chern , Wei-Fu Lin , Chia-Chu Chen

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

Neurons and Cognition · Quantitative Biology 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

Conventional wisdom suggests that environmental noise drives populations toward extinction. In contrast, we report a paradoxical phenomenon in which stochasticity reverses a deterministic tipping point, thereby preventing collapse. Using a…

Populations and Evolution · Quantitative Biology 2025-07-08 Vinesh Vijayan , B Priyadharshini , R Sathish Kumar , G Janaki
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