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Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

With the rapid progress of Large Language Models (LLMs), the general public now has easy and affordable access to applications capable of answering most health-related questions in a personalized manner. These LLMs are increasingly proving…

Artificial Intelligence · Computer Science 2025-10-20 Emma Kondrup , Anne Imouza

Developing accurate biomedical Question Answering (QA) systems in low-resource languages remains a major challenge, limiting equitable access to reliable medical knowledge. This paper introduces BanglaMedQA and BanglaMMedBench, the first…

Computation and Language · Computer Science 2025-11-07 Sadia Sultana , Saiyma Sittul Muna , Mosammat Zannatul Samarukh , Ajwad Abrar , Tareque Mohmud Chowdhury

Retrieval-Augmented Generation (RAG) architectures have recently garnered significant attention for their ability to improve truth grounding and coherence in natural language processing tasks. However, the reliability of RAG systems in…

Computation and Language · Computer Science 2024-12-04 Joel Suro

State-of-the-art question answering (QA) models exhibit a variety of social biases (e.g., with respect to sex or race), generally explained by similar issues in their training data. However, what has been overlooked so far is that in the…

Computation and Language · Computer Science 2023-10-17 Sagi Shaier , Kevin Bennett , Lawrence Hunter , Katharina von der Wense

In Large Language Models, Retrieval-Augmented Generation (RAG) systems can significantly enhance the performance of large language models by integrating external knowledge. However, RAG also introduces new security risks. Existing research…

Machine Learning · Computer Science 2025-06-16 Linlin Wang , Tianqing Zhu , Laiqiao Qin , Longxiang Gao , Wanlei Zhou

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Medical question answering requires extensive access to specialized conceptual knowledge. The current paradigm, Retrieval-Augmented Generation (RAG), acquires expertise medical knowledge through large-scale corpus retrieval and uses this…

Computation and Language · Computer Science 2025-02-20 Sichu Liang , Linhai Zhang , Hongyu Zhu , Wenwen Wang , Yulan He , Deyu Zhou

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

The paradigm of retrieval-augmented generated (RAG) helps mitigate hallucinations of large language models (LLMs). However, RAG also introduces biases contained within the retrieved documents. These biases can be amplified in scenarios…

Computation and Language · Computer Science 2025-06-24 Bryan Li , Fiona Luo , Samar Haider , Adwait Agashe , Tammy Li , Runqi Liu , Muqing Miao , Shriya Ramakrishnan , Yuan Yuan , Chris Callison-Burch

Biases in large language models (LLMs) often manifest as systematic distortions in associations between demographic attributes and professional or social roles, reinforcing harmful stereotypes across gender, ethnicity, and geography. This…

Computation and Language · Computer Science 2026-03-10 Ravi Ranjan , Utkarsh Grover , Agorista Polyzou

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Retrieval-Augmented Generation (RAG) has gained significant attention in recent years for its potential to enhance natural language understanding and generation by combining large-scale retrieval systems with generative models. RAG…

Computation and Language · Computer Science 2025-03-18 Mingyue Cheng , Yucong Luo , Jie Ouyang , Qi Liu , Huijie Liu , Li Li , Shuo Yu , Bohou Zhang , Jiawei Cao , Jie Ma , Daoyu Wang , Enhong Chen

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

Computation and Language · Computer Science 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

Recent advancements in Large Language Models (LLMs) have positioned them as powerful tools for clinical decision-making, with rapidly expanding applications in healthcare. However, concerns about bias remain a significant challenge in the…

Artificial Intelligence · Computer Science 2024-10-23 Kenza Benkirane , Jackie Kay , Maria Perez-Ortiz

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by retrieving relevant document from external knowledge sources. By referencing this external knowledge, RAG effectively reduces the generation of factually…

Computation and Language · Computer Science 2025-04-22 Zheng Zhang , Ning Li , Qi Liu , Rui Li , Weibo Gao , Qingyang Mao , Zhenya Huang , Baosheng Yu , Dacheng Tao

Recent studies have demonstrated that large language models (LLMs) exhibit significant biases in evaluation tasks, particularly in preferentially rating and favoring self-generated content. However, the extent to which this bias manifests…

Computation and Language · Computer Science 2025-12-09 Yen-Shan Chen , Jing Jin , Peng-Ting Kuo , Chao-Wei Huang , Yun-Nung Chen

Medical question answering (QA) is a reasoning-intensive task that remains challenging for large language models (LLMs) due to hallucinations and outdated domain knowledge. Retrieval-Augmented Generation (RAG) provides a promising…

Computation and Language · Computer Science 2025-05-01 Xuanzhao Dong , Wenhui Zhu , Hao Wang , Xiwen Chen , Peijie Qiu , Rui Yin , Yi Su , Yalin Wang

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Retrieval-Augmented Generation (RAG) is an effective approach to enhance the factual accuracy of large language models (LLMs) by retrieving information from external databases, which are typically composed of diverse sources, to supplement…

Machine Learning · Computer Science 2025-10-15 Jeongyeon Hwang , Junyoung Park , Hyejin Park , Dongwoo Kim , Sangdon Park , Jungseul Ok