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Wearable devices record physiological and behavioral signals that can improve health predictions. While foundation models are increasingly used for such predictions, they have been primarily applied to low-level sensor data, despite…

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

A deep latent variable model is a powerful method for capturing complex distributions. These models assume that underlying structures, but unobserved, are present within the data. In this dissertation, we explore high-dimensional problems…

Machine Learning · Computer Science 2024-06-13 Khuong Vo

Wearable foundation models (WFMs), trained on large volumes of data collected by affordable, always-on devices, have demonstrated strong performance on short-term, well-defined health monitoring tasks, including activity recognition,…

Machine Learning · Computer Science 2026-03-23 Yu Yvonne Wu , Yuwei Zhang , Hyungjun Yoon , Ting Dang , Dimitris Spathis , Tong Xia , Qiang Yang , Jing Han , Dong Ma , Sung-Ju Lee , Cecilia Mascolo

We propose a new class of waveform foundation models that departs from conventional sequence based representations by modeling physiological time series as realizations of latent event processes. Rather than treating signals as collections…

Machine Learning · Computer Science 2026-05-12 Li Na , Yuanyun Zhang , Shi Li

Pretrained foundation models and transformer architectures have driven the success of large language models (LLMs) and other modern AI breakthroughs. However, similar advancements in health data modeling remain limited due to the need for…

Machine Learning · Computer Science 2025-07-01 Franklin Y. Ruan , Aiwei Zhang , Jenny Y. Oh , SouYoung Jin , Nicholas C. Jacobson

Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…

Machine Learning · Computer Science 2026-04-07 Qian Zhou , Yuanyun Zhang , Shi Li

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

The great behavioral heterogeneity observed between individuals with the same psychiatric disorder and even within one individual over time complicates both clinical practice and biomedical research. However, modern technologies are an…

Neurons and Cognition · Quantitative Biology 2023-05-25 Michaela Ennis

The recent shift to remote learning and work has aggravated long-standing problems, such as the problem of monitoring the mental health of individuals and the progress of students towards learning targets. We introduce a novel latent…

Applications · Statistics 2023-10-13 Minjeong Jeon , Michael Schweinberger

Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Adam Tupper , Christian Gagné

Foundation models have recently gained significant attention because of their generalizability and adaptability across multiple tasks and data distributions. Although medical foundation models have emerged, solutions for cardiac imaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Sekeun Kim , Pengfei Jin , Sifan Song , Cheng Chen , Yiwei Li , Hui Ren , Xiang Li , Tianming Liu , Quanzheng Li

Recent advances in remote patient monitoring (RPM) systems can recognize various human activities to measure vital signs, including subtle motions from superficial vessels. There is a growing interest in applying artificial intelligence…

Machine Learning · Computer Science 2022-09-29 Thanveer Shaik , Xiaohui Tao , Niall Higgins , Raj Gururajan , Yuefeng Li , Xujuan Zhou , U Rajendra Acharya

Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of…

We survey applications of pretrained foundation models in robotics. Traditional deep learning models in robotics are trained on small datasets tailored for specific tasks, which limits their adaptability across diverse applications. In…

Psychiatric patients' passive activity monitoring is crucial to detect behavioural shifts in real-time, comprising a tool that helps clinicians supervise patients' evolution over time and enhance the associated treatments' outcomes.…

Signal Processing · Electrical Eng. & Systems 2022-11-21 Fernando Moreno-Pino , María Martínez-García , Pablo M. Olmos , Antonio Artés-Rodríguez

We present a foundation model-derived method to identify highly informative tokens and events in electronic health records. Our approach considers incoming data in the entire context of a patient's hospitalization and so can flag anomalous…

Machine Learning · Computer Science 2025-07-31 Michael C. Burkhart , Bashar Ramadan , Luke Solo , William F. Parker , Brett K. Beaulieu-Jones

In computational pathology, several foundation models have recently emerged and demonstrated enhanced learning capability for analyzing pathology images. However, adapting these models to various downstream tasks remains challenging,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Jeaung Lee , Jeewoo Lim , Keunho Byeon , Jin Tae Kwak

Foundation models trained on electronic health records show strong performance on many clinical prediction tasks but are limited by sparse and irregular documentation. Wearable devices provide dense continuous physiological signals but lack…

Machine Learning · Computer Science 2026-01-21 Yuanyun Zhang , Han Zhou , Li Feng , Yilin Hong , Shi Li

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu
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