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Glaucoma is a major cause of irreversible blindness, with significant diagnostic subjectivity. This inherent uncertainty, combined with the overconfidence of models optimized solely for accuracy can lead to fatal issues such as…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Taejin Jeong , Joohyeok Kim , Jaehoon Joo , Seong Jae Hwang

Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Fabian A. Braeu , Alexandre H. Thiéry , Tin A. Tun , Aiste Kadziauskiene , George Barbastathis , Tin Aung , Michaël J. A. Girard

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

This research work reveals the strengths of intertwining a deep custom convolutional neural network with a disruptive Vision Transformer, both fused together with a radical Cross-Attention module. Here, two high-yielding datasets for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Ramanathan Swaminathan

Breast cancer is the second leading cause of cancer-related death after lung cancer in women. Early detection of breast cancer in X-ray mammography is believed to have effectively reduced the mortality rate. However, a relatively high false…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Xuejiao Tang , Liuhua Zhang , Wenbin Zhang , Xin Huang , Vasileios Iosifidis , Zhen Liu , Mingli Zhang , Enza Messina , Ji Zhang

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

Machine Learning · Computer Science 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 José Ignacio Orlando , João Barbosa Breda , Karel van Keer , Matthew B. Blaschko , Pablo J. Blanco , Carlos A. Bulant

Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Zhiyuan Cai , Li Lin , Huaqing He , Xiaoying Tang

Purpose: A major barrier to the implementation of artificial intelligence for medical applications is the lack of explainability and high confidence for incorrect decisions, specifically with out-of-domain samples. We propose a…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Mikyla K. Bowen , Jesse W. Wilson

Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Gauri Naik , Nandini Narvekar , Dimple Agarwal , Nishita Nandanwar , Himangi Pande

This investigation reports on the results of convolutional neural networks developed for the recently introduced PathologicAL Myopia (PALM) dataset, which consists of 1200 fundus images. We propose a new Optic Nerve Head (ONH)-based…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Ruben Hemelings , Bart Elen , Matthew B. Blaschko , Julie Jacob , Ingeborg Stalmans , Patrick De Boever

Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Sachin Kumar , Sumita Mishra , Pallavi Asthana , Pragya

Skin cancer, a major form of cancer, is a critical public health problem with 123,000 newly diagnosed melanoma cases and between 2 and 3 million non-melanoma cases worldwide each year. The leading cause of skin cancer is high exposure of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Saket S. Chaturvedi , Kajol Gupta , Prakash. S. Prasad

Glaucoma disease progression, as measured by visual field (VF) data, is often defined by periods of relative stability followed by an abrupt decrease in visual ability at some point in time. Determining the transition point of the disease…

Applications · Statistics 2018-11-28 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

Given the size of modern cities in the urbanising age, it is beyond the perceptual capacity of most people to develop a good knowledge about the beauty and ugliness of the city at every street corner. Correspondingly, for planners, it is…

Computer Vision and Pattern Recognition · Computer Science 2016-08-12 Lun Liu , Hui Wang , Chunyang Wu

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

Glaucoma is a leading cause of irreversible blindness worldwide, emphasizing the critical need for early detection and intervention. In this paper, we present DeepEyeNet, a novel and comprehensive framework for automated glaucoma detection…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Angshuman Roy , Anuvab Sen , Soumyajit Gupta , Soham Haldar , Subhrajit Deb , Taraka Nithin Vankala , Arkapravo Das

In ophthalmology, intravitreal operative medication therapy (IVOM) is a widespread treatment for diseases related to the age-related macular degeneration (AMD), the diabetic macular edema (DME), as well as the retinal vein occlusion (RVO).…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Tobias Schlosser , Frederik Beuth , Trixy Meyer , Arunodhayan Sampath Kumar , Gabriel Stolze , Olga Furashova , Katrin Engelmann , Danny Kowerko

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya

Skin cancer is the most common human malignancy(American Cancer Society) which is primarily diagnosed visually, starting with an initial clinical screening and followed potentially by dermoscopic(related to skin) analysis, a biopsy and…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Kartikeya Agarwal , Tismeet Singh