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Synthetic molecular dynamics (synMD) trajectories from learned generative models have been proposed as a useful addition to the biomolecular simulation toolbox. The computational expense of explicitly integrating the equations of motion in…

Computational Physics · Physics 2022-05-05 John D. Russo , Daniel M. Zuckerman

The development of porous polymeric membranes remains a labor-intensive process, often requiring extensive trial and error to identify optimal fabrication parameters. In this study, we present a fully automated platform for membrane…

Molecular carriers represent an increasingly common strategy in the field of nanopore sensing to use secondary molecules to selectively report on the presence of target analytes in solution, allowing for sensitive assays of otherwise…

Biomolecules · Quantitative Biology 2023-05-10 Zachary Roelen , Vincent Tabard-Cossa

While nuclear magnetic resonance (NMR) provides valuable insights into the local environment of many nuclei, the unambiguous interpretation of the signal in terms of microscopic dynamics is often difficult, particularly when the quadrupolar…

Chemical Physics · Physics 2025-02-11 Matthieu Wolf , Iurii Chubak , Benjamin Rotenberg

We report on systematic numerical study of carrier multiplication (CM) processes in spherically symmetric nanocrystal (NC) and bulk forms of PbSe and PbS representing the test bed for understanding basic aspects of CM dynamics. The adopted…

Mesoscale and Nanoscale Physics · Physics 2015-05-30 Kirill A. Velizhanin , Andrei Piryatinski

Direct measurements of photoexcited carrier dynamics in nickel are made using few-femtosecond extreme ultraviolet (XUV) transient absorption spectroscopy at the nickel M$_{2,3}$ edge. It is observed that the core-level absorption lineshape…

In this paper, we present the design and the analysis of an electrochemical circuit for measuring the concentrations of therapeutic drugs using structure-switching aptamers. Aptamers are single-stranded nucleic acids, whose sequence is…

Signal Processing · Electrical Eng. & Systems 2020-05-08 Jun-Chau Chien , Sam W. Baker , H. Tom Soh , Amin Arbabian

Nonnegative matrix factorization (NMF) methods have proved to be powerful across a wide range of real-world clustering applications. Integrating multiple types of measurements for the same objects/subjects allows us to gain a deeper…

Machine Learning · Computer Science 2014-09-16 Daniel Hidru , Anna Goldenberg

Recently there has been an increased interest to apply the sensitive $\beta$-decay asymmetry detected nuclear magnetic resonance ($\beta$-NMR) technique to biological studies. A liquid-sample $\beta$-NMR setup was build at ISOLDE to allow…

The identification of continuous-time (CT) systems from discrete-time (DT) input and output signals, i.e., the sampled data, has received considerable attention for half a century. The state-of-the-art methods are parametric methods and…

Systems and Control · Electrical Eng. & Systems 2024-10-29 Xiaozhu Fang , Biqiang Mu , Tianshi Chen

Model compression has gained a lot of attention due to its ability to reduce hardware resource requirements significantly while maintaining accuracy of DNNs. Model compression is especially useful for memory-intensive recurrent neural…

Machine Learning · Computer Science 2018-05-30 Dongsoo Lee , Byeongwook Kim

In magnetically-confined plasmas of tokamaks, neutral deuterium/hydrogen (D/H) atoms play a role in energy, momentum, and particle balance, as well as the stabilization of plasma turbulence. One key important fusion performance parameter is…

Applied Physics · Physics 2019-12-10 David Feng , Ahmed Diallo , Mikhail N. Shneider

Being capable of characterizing DNA local bending is essential to understand thoroughly many biological processes because they involve a local bending of the double helix axis, either intrinsic to the sequence or induced by the binding of…

Nuclear Magnetic Resonance (NMR) spectroscopy is a central characterization method for molecular structure elucidation, yet interpreting NMR spectra to deduce molecular structures remains challenging due to the complexity of spectral data…

Chemical Physics · Physics 2025-07-15 Qingsong Yang , Binglan Wu , Xuwei Liu , Bo Chen , Wei Li , Gen Long , Xin Chen , Mingjun Xiao

Purpose: Inhomogeneous magnetization transfer (ihMT) effect reflects dipolar order with a dipolar relaxation time ($T_{1D}$), specific to motion-restricted macromolecules. We aim to quantify $T_{1D}$ using spin-lock MRI technique. Methods:…

Medical Physics · Physics 2026-01-06 Zijian Gao , Qianxue Shan , Ziqin Zhou , Ziqiang Yu , Weitian Chen

Advanced tensor decomposition, such as Tensor train (TT) and Tensor ring (TR), has been widely studied for deep neural network (DNN) model compression, especially for recurrent neural networks (RNNs). However, compressing convolutional…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Miao Yin , Yang Sui , Siyu Liao , Bo Yuan

The Density Matrix Renormalization Group (DMRG) method has become a prominent tool for simulating strongly correlated electronic systems characterized by dominant static correlation effects. However, capturing the full scope of electronic…

Chemical Physics · Physics 2024-11-13 Nicholas Bauman , Libor Veis , Karol Kowalski , Jiri Brabec

Fluorescent nanodiamonds (FNDs) relaxometry holds promising future for advancement of high spatiotemporal resolution metabolic imaging technology. In this study, we demonstrate a simultaneous integration of spatial position tracking with…

Biological Physics · Physics 2025-12-23 Jia Su , Linyu Zeng , Pengyu Chen , Zenghao Kong , Fazhan Shi

Single-cell analysis can unravel functional heterogeneity within cell populations otherwise obscured by ensemble measurements. However, non-invasive techniques that probe chemical entities and their dynamics are still lacking. This…

Applied Physics · Physics 2023-06-14 Nick Ruben Neuling , Robin Derek Allert , Dominik Benjamin Bucher

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty