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Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

This paper examines an epidemic patch model with mass-action transmission mechanism and asymmetric connectivity matrix. Results on the global dynamics of solutions and the spatial structures of endemic solutions are obtained. In particular,…

Classical Analysis and ODEs · Mathematics 2023-11-14 Rachidi Salako , Yixiang Wu

We consider the edge-based compartmental models for infectious disease spread introduced in Part I. These models allow us to consider standard SIR diseases spreading in random populations. In this paper we show how to handle deviations of…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Erik M. Volz

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

The paradigm for compartment models in epidemiology assumes exponentially distributed incubation and removal times, which is not realistic in actual populations. Commonly used variations with multiple exponentially distributed variables are…

Populations and Evolution · Quantitative Biology 2021-02-10 P. Hernández , C. Pena , A. Ramos , J. J. Gómez-Cadenas

We develop a theoretical approach that uses physiochemical kinetics modelling to describe cell population dynamics upon progression of viral infection in cell culture, which results in cell apoptosis (programmed cell death) and necrosis…

Quantitative Methods · Quantitative Biology 2016-12-30 Sergii Domanskyi , Joshua E. Schilling , Vyacheslav Gorshkov , Sergiy Libert , Vladimir Privman

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

We show how the standard field theoretical language based on creation and annihilation operators may be used for a straightforward derivation of closed master equations describing the population dynamics of multivariate stochastic epidemic…

Biological Physics · Physics 2016-03-08 Leonardo Mondaini

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

Metapopulation models are commonly used in ecology, evolution, and epidemiology. These models usually entail homogeneity assumptions within patches and study networks of migration between patches to generate insights into conservation of…

Populations and Evolution · Quantitative Biology 2025-06-06 Diepreye Ayabina , Hasan Sevil , Adam Kleczkowski , M. Gabriela M. Gomes

Recently developed techniques to acquire high-quality human mobility data allow large-scale simulations of the spread of infectious diseases with high spatial and temporal resolution.Analysis of such data has revealed the oversimplification…

Physics and Society · Physics 2015-12-08 Naoya Fujiwara , Abhijeet R. Sonawane , Koji Iwayama , Kazuyuki Aihara

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

These notes describe stochastic epidemics in a homogenous community. Our main concern is stochastic compartmental models (i.e. models where each individual belongs to a compartment, which stands for its status regarding the epidemic under…

Probability · Mathematics 2020-02-06 Tom Britton , Etienne Pardoux

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

We study the diffusion of epidemics on networks that are partitioned into local communities. The gross structure of hierarchical networks of this kind can be described by a quotient graph. The rationale of this approach is that individuals…

Social and Information Networks · Computer Science 2016-01-19 Stefano Bonaccorsi , Stefania Ottaviano , Delio Mugnolo , Francesco De Pellegrini

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

We propose a new stochastic epidemiological model defined in a continuous space of arbitrary dimension, based on SIS dynamics implemented in a spatial $\Lambda$-Fleming-Viot (SLFV) process. The model can be described by as little as three…

Probability · Mathematics 2026-01-09 Apolline Louvet , Bastian Wiederhold

A model describing the dynamics related to the spreading of non-lethal infectious diseases in a fixed-size population is proposed. The model consists of a non-linear delay-differential equation describing the time evolution of the increment…

Populations and Evolution · Quantitative Biology 2010-10-05 A. Noviello , F. Romeo , R. De Luca

Models of infectious diseases have been developed since the first half of the twentieth century. Most models haven't considered the role that emotional factors of the individual may play on the population's behavioral adaptation during the…

Populations and Evolution · Quantitative Biology 2012-10-17 F. Nuñez , C. Ravello , H. Urbina , T. Perez-Acle