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Despite seasonal cholera outbreaks in Bangladesh, little is known about the relationship between environmental conditions and cholera cases. We seek to develop a predictive model for cholera outbreaks in Bangladesh based on environmental…

Cholera, a severe gastrointestinal infection caused by the bacterium Vibrio cholerae, remains a major threat to public health with a yearly estimated global burden of 2.9 million cases. Although the majority of existing models for the…

Dynamical Systems · Mathematics 2021-05-27 Beryl Musundi

Despite extensive control efforts over the centuries, cholera remains a globally significant health issue. Seasonal emergence of cholera cases has been reported, particularly in the Bengal delta region, which is often synchronized with…

Populations and Evolution · Quantitative Biology 2025-03-31 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Jon Pitchford , Joydev Chattopadhyay

We propose a multi-patch model of cholera transmission integrating environmental contamination, human mobility, and nutritional vulnerability. The population is stratified by food security status, and transmission occurs via human contact,…

Populations and Evolution · Quantitative Biology 2025-09-09 Jean-Marc Mandeng

This study presents a seasonally forced cholera model that incorporates imperfect vaccination as a control strategy. The model captures the temporal dynamics of susceptible, vaccinated, infected, and recovered individuals, as well as the…

Populations and Evolution · Quantitative Biology 2025-07-15 Eric Herrison Gyamfi

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Sequential Monte Carlo methods are a powerful framework for approximating the posterior distribution of a state variable in a sequential manner. They provide an attractive way of analyzing dynamic systems in real-time, taking into account…

Populations and Evolution · Quantitative Biology 2024-08-29 Dhorasso Temfack , Jason Wyse

Cholera continues to be a global health threat. Understanding how cholera spreads between locations is fundamental to the rational, evidence-based design of intervention and control efforts. Traditionally, cholera transmission models have…

Public health decisions must be made about when and how to implement interventions to control an infectious disease epidemic. These decisions should be informed by data on the epidemic as well as current understanding about the transmission…

Applications · Statistics 2024-08-15 Jesse Wheeler , AnnaElaine Rosengart , Zhuoxun Jiang , Kevin Tan , Noah Treutle , Edward Ionides

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

Infectious disease transmission is often modelled by discrete-valued stochastic state-transition processes. Due to a lack of complete data, Bayesian inference for these models often relies on data-augmentation techniques. These techniques…

Objectives: Our research adopts computational techniques to analyze disease outbreaks weekly over a large geographic area while maintaining local-level analysis by incorporating relevant high-spatial resolution cultural and environmental…

Machine Learning · Computer Science 2024-11-12 Scott Pezanowski , Etien Luc Koua , Joseph C Okeibunor , Abdou Salam Gueye

We investigate the source detection problem in epidemiology, which is one of the most important issues for control of epidemics. Mathematically, we reformulate the problem as one of identifying the relevant component in a multivariate…

Methodology · Statistics 2021-06-09 Jun Li , Juliane Manitz , Enrico Bertuzzo , Eric D. Kolaczyk

Mathematical models of cholera and waterborne disease vary widely in their structures, in terms of transmission pathways, loss of immunity, and other features. These differences may yield different predictions and parameter estimates from…

Populations and Evolution · Quantitative Biology 2016-05-24 Elizabeth C. Lee , Michael R. Kelly , Brad M. Ochocki , Segun M. Akinwumi , Karen E. S. Hamre , Joseph H. Tien , Marisa C. Eisenberg

The effective control of infectious diseases relies on accurate assessment of the impact of interventions, which is often hindered by the complex dynamics of the spread of disease. A Beta-Dirichlet switching state-space transmission model…

Methodology · Statistics 2024-04-30 Jingxue Feng , Liangliang Wang

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

Cholera remains a significant public health challenge globally, particularly affecting regions with inadequate water, sanitation, and hygiene infrastructures. This study presents a comprehensive mathematical model extending the classical…

Dynamical Systems · Mathematics 2025-05-15 Abdallah Alsammani , Gassan A. M. O. Farah , Mohammed A. Y. Mohammed , Mehmet Yavuz

The purpose of time series analysis via mechanistic models is to reconcile the known or hypothesized structure of a dynamical system with observations collected over time. We develop a framework for constructing nonlinear mechanistic models…

Statistics Theory · Mathematics 2009-06-08 Carles Bretó , Daihai He , Edward L. Ionides , Aaron A. King

Epidemiologists aiming to model the dynamics of global events face a significant challenge in identifying the factors linked with anomalies such as disease outbreaks. In this paper, we present a novel method for identifying the most…

Machine Learning · Computer Science 2021-09-20 Aboli Marathe , Saloni Parekh , Harsh Sakhrani
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