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In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

In this paper, we explore a strong baseline for crowd counting and an unsupervised people localization algorithm based on estimated density maps. Firstly, existing methods achieve state-of-the-art performance based on different backbones…

Computer Vision and Pattern Recognition · Computer Science 2020-11-10 Liangzi Rong , Chunping Li

Encoding the distance between locations in space is essential for accurate navigation. Grid cells, a functional class of neurons in medial entorhinal cortex, are believed to support this computation. However, existing theories of how…

Neurons and Cognition · Quantitative Biology 2025-11-12 Pritipriya Dasbehera , Akshunna S. Dogra , William T. Redman

This paper aims to count arbitrary objects in images. The leading counting approaches start from point annotations per object from which they construct density maps. Then, their training objective transforms input images to density maps…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Zenglin Shi , Pascal Mettes , Cees G. M. Snoek

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Estimating crowd count in densely crowded scenes is an extremely challenging task due to non-uniform scale variations. In this paper, we propose a novel end-to-end cascaded network of CNNs to jointly learn crowd count classification and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-17 Vishwanath A. Sindagi , Vishal M. Patel

Denoising generative models, such as diffusion and flow-based models, produce high-quality samples but require many denoising steps due to discretization error. Flow maps, which estimate the average velocity between timesteps, mitigate this…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Kyungmin Lee , Sihyun Yu , Jinwoo Shin

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Image geolocalization, inferring the geographic location of an image, is a challenging computer vision problem with many potential applications. The recent state-of-the-art approach to this problem is a deep image classification approach in…

Computer Vision and Pattern Recognition · Computer Science 2017-05-16 Nam Vo , Nathan Jacobs , James Hays

In this paper, we consider the problem of crowd counting in images. Given an image of a crowded scene, our goal is to estimate the density map of this image, where each pixel value in the density map corresponds to the crowd density at the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Mohammad Asiful Hossain , Mehrdad Hosseinzadeh , Omit Chanda , Yang Wang

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Cell detection and segmentation are integral parts of automated systems in digital pathology. Encoder-decoder networks have emerged as a promising solution for these tasks. However, training of these networks has typically required full…

Cell tracking enables data extraction from time-lapse "cell movies" and promotes modeling biological processes at the single-cell level. We introduce a new fully automated computational strategy to track accurately cells across frames in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Athanasios D. Balomenos , Panagiotis Tsakanikas , Elias S. Manolakos

The comparison of heterogeneous samples extensively exists in many applications, especially in the task of image classification. In this paper, we propose a simple but effective coupled neural network, called Deeply Coupled Autoencoder…

Computer Vision and Pattern Recognition · Computer Science 2014-02-11 Wen Wang , Zhen Cui , Hong Chang , Shiguang Shan , Xilin Chen

Sampling and quantization are standard practices in signal and image processing, but a theoretical understanding of their impact is incomplete. We consider discrete image registration when the underlying function is a one-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Serap A. Savari

Generative modeling over discrete structures underpins applications across deep learning, from biological sequence design and code generation to large language models, yet generation often remains sequential, relying on autoregressive…

Machine Learning · Computer Science 2026-05-11 Fred Zhangzhi Peng , Avishek Joey Bose , Anru R. Zhang , Alexander Tong

Learning-based denoising algorithms achieve state-of-the-art performance across various denoising tasks. However, training such models relies on access to large training datasets consisting of clean and noisy image pairs. On the other hand,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Ali Zafari , Xi Chen , Shirin Jalali

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

We develop Self2Seg, a self-supervised method for the joint segmentation and denoising of a single image. To this end, we combine the advantages of variational segmentation with self-supervised deep learning. One major benefit of our method…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Nadja Gruber , Johannes Schwab , Noémie Debroux , Nicolas Papadakis , Markus Haltmeier