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We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

In low-visibility marine environments characterized by turbidity and darkness, acoustic cameras serve as visual sensors capable of generating high-resolution 2D sonar images. However, acoustic camera images are interfered with by complex…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Xiaoteng Zhou , Katsunori Mizuno , Yilong Zhang

This study introduces a novel data-centric approach to improve real-time surgical guidance using fiber-based fluorescence lifetime imaging (FLIm). A key aspect of the methodology is the accurate detection of the aiming beam, which is…

Artificial Intelligence · Computer Science 2024-11-13 Mohamed Abul Hassan , Pu Sun , Xiangnan Zhou , Lisanne Kraft , Kelsey T Hadfield , Katjana Ehrlich , Jinyi Qi , Andrew Birkeland , Laura Marcu

Image denoising is a fundamental problem in computational photography, where achieving high perception with low distortion is highly demanding. Current methods either struggle with perceptual quality or suffer from significant distortion.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Tong Li , Hansen Feng , Lizhi Wang , Zhiwei Xiong , Hua Huang

FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…

Quantitative Methods · Quantitative Biology 2017-01-09 Bryan Kaye , Peter J. Foster , Tae Yeon Yoo , Daniel J. Needleman

Fluorescence lifetime imaging microscopy (FLIM) provides detailed information about molecular interactions and biological processes. A major bottleneck for FLIM is image resolution at high acquisition speeds, due to the engineering and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Valentin Kapitány , Areeba Fatima , Vytautas Zickus , Jamie Whitelaw , Ewan McGhee , Robert Insall , Laura Machesky , Daniele Faccio

Modern digital cameras rely on the sequential execution of separate image processing steps to produce realistic images. The first two steps are usually related to denoising and demosaicking where the former aims to reduce noise from the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Filippos Kokkinos , Stamatios Lefkimmiatis

Recently, self-supervised neural networks have shown excellent image denoising performance. However, current dataset free methods are either computationally expensive, require a noise model, or have inadequate image quality. In this work we…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Youssef Mansour , Reinhard Heckel

We introduce a novel approach to single image denoising based on the Blind Spot Denoising principle, which we call MAsked and SHuffled Blind Spot Denoising (MASH). We focus on the case of correlated noise, which often plagues real images.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Hamadi Chihaoui , Paolo Favaro

Aiming to reconstruct visual stimuli from brain signals, brain decoding has recently made significant progress using functional magnetic resonance imaging (fMRI). However, it still has challenging issues such as substantial individual…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Shuai Jiang , Zhu Meng , Haiwen Li , Delong Liu , Fei Su , Zhicheng Zhao

In machine learning approach to image denoising a network is trained to recover a clean image from a noisy one. In this paper a novel structure is proposed based on training multiple specialized networks as opposed to existing structures…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Seyed Mohsen Hosseini

Light field microscopy (LFM) has gained significant attention due to its ability to capture snapshot-based, large-scale 3D fluorescence images. However, existing LFM reconstruction algorithms are highly sensitive to sensor noise or require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Jiayin Zhao , Zhenqi Fu , Tao Yu , Hui Qiao

Variability of IVIM parameters throughout the literature is a long-standing issue, and perfusion-related parameters are difficult to interpret. We demonstrate for improving the analysis of intravoxel incoherent motion imaging (IVIM)…

Medical Physics · Physics 2024-01-05 Caleb Sample , Jonn Wu , Haley Clark

Fluorescence microscopy has enabled a dramatic development in modern biology. Due to its inherently weak signal, fluorescence microscopy is not only much noisier than photography, but also presented with Poisson-Gaussian noise where Poisson…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Yide Zhang , Yinhao Zhu , Evan Nichols , Qingfei Wang , Siyuan Zhang , Cody Smith , Scott Howard

Noise is an important factor that degrades the quality of medical images. Impulse noise is a common noise, which is caused by malfunctioning of sensor elements or errors in the transmission of images. In medical images due to presence of…

Computer Vision and Pattern Recognition · Computer Science 2017-10-13 Zohreh HosseinKhani , Mohsen Hajabdollahi , Nader Karimi , Reza Soroushmehr , Shahram Shirani , Kayvan Najarian , Shadrokh Samavi

Diffusion models excel in generating high-quality images. However, current diffusion models struggle to produce reliable images without guidance methods, such as classifier-free guidance (CFG). Are guidance methods truly necessary?…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Donghoon Ahn , Jiwon Kang , Sanghyun Lee , Jaewon Min , Minjae Kim , Wooseok Jang , Hyoungwon Cho , Sayak Paul , SeonHwa Kim , Eunju Cha , Kyong Hwan Jin , Seungryong Kim

Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Bhavesh Sandbhor , Bheeshm Sharma , Balamurugan Palaniappan

Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…

Computer Vision and Pattern Recognition · Computer Science 2013-06-10 Ji Won Yoon