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The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Geoffrey H. Tison , Jeffrey Zhang , Francesca N. Delling , Rahul C. Deo

Automated analysis of 12-lead electrocardiogram (ECG) plays a crucial role in the early screening and management of cardiovascular diseases (CVDs). In practice, it is common to see multiple co-occurring cardiac disorders, i.e., multi-label…

Signal Processing · Electrical Eng. & Systems 2023-06-07 Eedara Prabhakararao , Samarendra Dandapt

Cardiovascular diseases (CVDs) remain the foremost cause of mortality worldwide, a burden worsened by a severe deficit of healthcare workers. Artificial intelligence (AI) agents have shown potential to alleviate this gap through automated…

Cardiovascular diseases, a leading cause of noncommunicable disease-related deaths, require early and accurate detection to improve patient outcomes. Taking advantage of advances in machine learning and deep learning, multiple approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Paula Ruiz-Barroso , Francisco M. Castro , José Miranda , Denisa-Andreea Constantinescu , David Atienza , Nicolás Guil

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf

Models of human motion commonly focus either on trajectory prediction or action classification but rarely both. The marked heterogeneity and intricate compositionality of human motion render each task vulnerable to the data degradation and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Anthony Bourached , Robert Gray , Xiaodong Guan , Ryan-Rhys Griffiths , Ashwani Jha , Parashkev Nachev

One of the major shortcomings of variational autoencoders is the inability to produce generations from the individual modalities of data originating from mixture distributions. This is primarily due to the use of a simple isotropic Gaussian…

Machine Learning · Computer Science 2019-12-02 Frantzeska Lavda , Magda Gregorová , Alexandros Kalousis

The task of predicting stochastic behaviors of road agents in diverse environments is a challenging problem for autonomous driving. To best understand scene contexts and produce diverse possible future states of the road agents adaptively…

Machine Learning · Computer Science 2022-01-25 Geunseob Oh , Huei Peng

The surrogate loss of variational autoencoders (VAEs) poses various challenges to their training, inducing the imbalance between task fitting and representation inference. To avert this, the existing strategies for VAEs focus on adjusting…

Neural and Evolutionary Computing · Computer Science 2024-04-02 Zhangkai Wu , Longbing Cao , Lei Qi

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

Machine Learning · Computer Science 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang

An electrocardiogram (ECG) is vital for identifying cardiac diseases, offering crucial insights for diagnosing heart conditions and informing potentially life-saving treatments. However, like other types of medical data, ECGs are subject to…

Signal Processing · Electrical Eng. & Systems 2024-07-17 Sergey Skorik , Aram Avetisyan

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

High failure rates in cardiac drug development necessitate virtual clinical trials via electrocardiogram (ECG) generation to reduce risks and costs. However, existing ECG generation models struggle to balance morphological realism with…

Machine Learning · Computer Science 2026-03-31 Qian Shao , Bang Du , Zepeng Li , Qiyuan Chen , Jiahe Chen , Hongxia Xu , Jimeng Sun , Jian Wu , Jintai Chen

Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

Machine Learning · Computer Science 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that appears between the second and forth decade of a patient's life, being responsible for 20% of sudden cardiac deaths before the age of 35. The…

Signal Processing · Electrical Eng. & Systems 2022-09-07 Vasileios E. Papageorgiou , Thomas Zegkos , Georgios Efthimiadis , George Tsaklidis

The label scarcity problem is the main challenge that hinders the wide application of deep learning systems in automatic cardiovascular diseases (CVDs) detection using electrocardiography (ECG). Tuning pre-trained models alleviates this…

Machine Learning · Computer Science 2024-11-18 Rushuang Zhou , Lei Clifton , Zijun Liu , Kannie W. Y. Chan , David A. Clifton , Yuan-Ting Zhang , Yining Dong

Ventricular arrhythmias (VA) are the main causes of sudden cardiac death. Developing machine learning methods for detecting VA based on electrocardiograms (ECGs) can help save people's lives. However, developing such machine learning models…

Machine Learning · Computer Science 2022-03-02 Wenrui Zhang , Shijia Geng , Zhaoji Fu , Linlin Zheng , Chenyang Jiang , Shenda Hong

In recent years, trace generation has emerged as a significant challenge within the Process Mining community. Deep Learning (DL) models have demonstrated accuracy in reproducing the features of the selected processes. However, current DL…

Electrocardiogram (ECG) signals, profiling the electrical activities of the heart, are used for a plethora of diagnostic applications. However, ECG systems require multiple leads or channels of signals to capture the complete view of the…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Nabil Ibtehaz , Masood Mortazavi

Electrocardiogram (ECG) analysis is a fundamental tool for diagnosing cardiovascular conditions, yet anomaly detection in ECG signals remains challenging due to their inherent complexity and variability. We propose Multi-scale Masked…

Machine Learning · Computer Science 2025-02-11 Ya Zhou , Yujie Yang , Jianhuang Gan , Xiangjie Li , Jing Yuan , Wei Zhao
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