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Experiments with both qualitative and quantitative factors occur frequently in practical applications. Many construction methods for this kind of designs, such as marginally coupled designs, were proposed to pursue some good space-filling…

Statistics Theory · Mathematics 2021-01-08 Mei Zhang , Feng Yang , Yongdao Zhou

Repeated-measure designs allow comparisons within a group as well as between groups, and are commonly referred to as split-plot designs. While originating in agricultural experiments, they are now widely used in medical research,…

Computation · Statistics 2025-12-22 Paavo Sattler , Nils Hichert

Difference sets and their generalisations to difference families arise from the study of designs and many other applications. Here we give a brief survey of some of these applications, noting in particular the diverse definitions of…

Discrete Mathematics · Computer Science 2015-10-23 S. -L. Ng , M. B. Paterson

Variational design is a well-recognized CAD technique due to the increased design efficiency. It often presents as a parametric family of CAD models. Although effective, this way of working cannot handle design requirements that go beyond…

Methodology · Statistics 2022-01-11 Qiang Zou , Qiqiang Zheng , Zhihong Tang , Shuming Gao

A common problem in Phase II clinical trials is the comparison of dose response curves corresponding to different treatment groups. If the effect of the dose level is described by parametric regression models and the treatments differ in…

Statistics Theory · Mathematics 2016-03-16 Chrystel Feller , Kirsten Schorning , Holger Dette , Georgina Bermann , Björn Bornkamp

We build on theoretical results from the mechanism design literature to analyze empirical models of second-degree price discrimination (2PD). We show that for a random-coefficients discrete choice ("BLP") model to be suitable for studying…

General Economics · Economics 2025-10-03 Soheil Ghili , K. Sudhir , Nitish Jain , Ankur Garg

This article provides an introduction to the Regression Discontinuity (RD) design, and its application to empirical research in the medical sciences. While the main focus of this article is on causal interpretation, key concepts of…

Methodology · Statistics 2025-08-07 Matias D. Cattaneo , Rocio Titiunik

By coordinating terminal smart devices or microprocessors to engage in cooperative computation to achieve systemlevel targets, distributed optimization is incrementally favored by both engineering and computer science. The well-known…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-24 Yu Yang , Xiaohong Guan , Qing-Shan Jia , Liang Yu , Bolun Xu , Costas J. Spanos

Design-based simulations - procedures that hold realized outcomes fixed and generate variation by resampling treatment assignment or shocks - are widely used in both methodological and applied work to assess inference procedures. This paper…

Econometrics · Economics 2026-03-13 Bruno Ferman

In experimental design, we are given $n$ vectors in $d$ dimensions, and our goal is to select $k\ll n$ of them to perform expensive measurements, e.g., to obtain labels/responses, for a linear regression task. Many statistical criteria have…

Machine Learning · Computer Science 2019-06-11 Michał Dereziński , Feynman Liang , Michael W. Mahoney

In this paper, we describe a computational implementation of the Synthetic difference-in-differences (SDID) estimator of Arkhangelsky et al. (2021) for Stata. Synthetic difference-in-differences can be used in a wide class of circumstances…

Econometrics · Economics 2023-02-14 Damian Clarke , Daniel Pailañir , Susan Athey , Guido Imbens

Exploration is crucial in the design process and is known for its essential role in fostering creativity and enhancing design outcomes. Within design teams, exploration evolves into co-exploration, a collaborative and dynamic practice that…

Human-Computer Interaction · Computer Science 2025-10-03 Xinhui Ye , Joep Frens , Jun Hu

High-quality computational and data-intensive (CDI) applications are critical for advancing research frontiers in almost all disciplines. Despite their importance, there is a significant gap due to the lack of comprehensive best practices…

Computational Engineering, Finance, and Science · Computer Science 2024-06-05 Parinaz Barakhshan , Rudolf Eigenmann

This article develops new closed-form variance expressions for power analyses for commonly used difference-in-differences (DID) and comparative interrupted time series (CITS) panel data estimators. The main contribution is to incorporate…

Methodology · Statistics 2021-10-18 Peter Z. Schochet

Suppose it is of interest to characterize effect heterogeneity of an intervention across levels of a baseline covariate using only pre- and post- intervention outcome measurements from those who received the intervention, i.e. with no…

Methodology · Statistics 2023-06-21 Zach Shahn

Diverse planning is the problem of finding multiple plans for a given problem specification, which is at the core of many real-world applications. For example, diverse planning is a critical piece for the efficiency of plan recognition…

Artificial Intelligence · Computer Science 2023-10-04 Mustafa F. Abdelwahed , Joan Espasa , Alice Toniolo , Ian P. Gent

Estimation frameworks for statistical inference are preferred to hypothesis testing when quantifying uncertainty and precise estimation are more valuable than binary decisions about statistical significance. Study design for…

Methodology · Statistics 2025-10-29 Luke Hagar , Nathaniel T. Stevens

We review typical design problems encountered in the planning of observational studies and propose a unifying framework that allows us to use the same concepts and notation for different problems. In the framework, the design is defined as…

Statistics Theory · Mathematics 2017-11-02 Juha Karvanen , Jarno Vanhatalo , Kari Auranen , Sangita Kulathinal , Samu Mäntyniemi

Regression discontinuity (RD) designs are popular quasi-experimental studies in which treatment assignment depends on whether the value of a running variable exceeds a cutoff. RD designs are increasingly popular in educational applications…

Methodology · Statistics 2024-07-23 Daryl Swartzentruber , Eloise Kaizar

There is a movement in design of experiments away from the classic randomization put forward by Fisher, Cochran and others to one based on optimization. In fixed-sample trials comparing two groups, measurements of subjects are known in…

Methodology · Statistics 2018-10-22 Adam Kapelner , Abba M. Krieger , Uri Shalit , David Azriel