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Objective: Clinical documentation contains factual, diagnostic, and management errors that can compromise patient safety. Large language models (LLMs) may help detect and correct such errors, but their behavior under different prompting…

Computation and Language · Computer Science 2025-11-27 Farzad Ahmed , Joniel Augustine Jerome , Meliha Yetisgen , Özlem Uzuner

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Given the growing trend of many organizations integrating Retrieval Augmented Generation (RAG) into their operations, we assess RAG on domain-specific data and test state-of-the-art models across various optimization techniques. We…

Artificial Intelligence · Computer Science 2024-11-14 Anum Afzal , Juraj Vladika , Gentrit Fazlija , Andrei Staradubets , Florian Matthes

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Large language models (LLMs) are a new and powerful tool for a wide span of applications involving natural language and demonstrate impressive code generation abilities. The goal of this work is to automatically generate tests and use these…

Artificial Intelligence · Computer Science 2024-03-12 Christian Munley , Aaron Jarmusch , Sunita Chandrasekaran

In real-world applications with Large Language Models (LLMs), external retrieval mechanisms - such as Search-Augmented Generation (SAG), tool utilization, and Retrieval-Augmented Generation (RAG) - are often employed to enhance the quality…

Computation and Language · Computer Science 2025-02-25 Tzu-Lin Kuo , Feng-Ting Liao , Mu-Wei Hsieh , Fu-Chieh Chang , Po-Chun Hsu , Da-Shan Shiu

Retrieval-augmented generation (RAG) has emerged as an approach to augment large language models (LLMs) by reducing their reliance on static knowledge and improving answer factuality. RAG retrieves relevant context snippets and generates an…

Computation and Language · Computer Science 2025-02-21 Juraj Vladika , Florian Matthes

We present a comprehensive study of answer quality evaluation in Retrieval-Augmented Generation (RAG) applications using vRAG-Eval, a novel grading system that is designed to assess correctness, completeness, and honesty. We further map the…

Computation and Language · Computer Science 2024-11-08 Yang Wang , Alberto Garcia Hernandez , Roman Kyslyi , Nicholas Kersting

Reward Modeling is critical in evaluating and improving the generation of Large Language Models (LLMs). While numerous recent works have shown its feasibility in improving safety, helpfulness, reasoning, and instruction-following ability,…

Computation and Language · Computer Science 2025-11-13 Hanning Zhang , Juntong Song , Juno Zhu , Yuanhao Wu , Tong Zhang , Cheng Niu

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Retrieval Augmented Generation (RAG) has emerged as a powerful application of Large Language Models (LLMs), revolutionizing information search and consumption. RAG systems combine traditional search capabilities with LLMs to generate…

Information Retrieval · Computer Science 2025-06-12 Harsh Maheshwari , Srikanth Tenneti , Alwarappan Nakkiran

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

Computation and Language · Computer Science 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah

Identifying disease phenotypes from electronic health records (EHRs) is critical for numerous secondary uses. Manually encoding physician knowledge into rules is particularly challenging for rare diseases due to inadequate EHR coding,…

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Recent advancements in Retrieval-Augmented Generation (RAG) have revolutionized natural language processing by integrating Large Language Models (LLMs) with external information retrieval, enabling accurate, up-to-date, and verifiable text…

Computation and Language · Computer Science 2025-04-22 Aoran Gan , Hao Yu , Kai Zhang , Qi Liu , Wenyu Yan , Zhenya Huang , Shiwei Tong , Guoping Hu

Generalized Entity Matching (GEM), which aims at judging whether two records represented in different formats refer to the same real-world entity, is an essential task in data management. The prompt tuning paradigm for pre-trained language…

Computation and Language · Computer Science 2024-05-09 Yikuan Xia , Jiazun Chen , Xinchi Li , Jun Gao

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

The effectiveness of Large Language Models (LLMs) in generating accurate responses relies heavily on the quality of input provided, particularly when employing Retrieval Augmented Generation (RAG) techniques. RAG enhances LLMs by sourcing…

Information Retrieval · Computer Science 2024-08-02 Spurthi Setty , Harsh Thakkar , Alyssa Lee , Eden Chung , Natan Vidra

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Developing the capacity to effectively search for requisite datasets is an urgent requirement to assist data users in identifying relevant datasets considering the very limited available metadata. For this challenge, the utilization of…

Information Retrieval · Computer Science 2024-10-08 Teruaki Hayashi , Hiroki Sakaji , Jiayi Dai , Randy Goebel