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Infrared (IR) spectroscopy has emerged as a pivotal tool in biomedical diagnostics, offering label-free spectral biomarkers for the detection of numerous diseases, particularly in the fingerprint region. However, the lack of rapid and…

Optics · Physics 2026-01-12 Xiangyu Zhao , Yuqing Liu , Jingzhu Shao , Longsheng Fang , Chongzhao Wu

Total Internal Reflection Microscopy (TIRM) is a sensitive non-invasive technique to measure the interaction potentials between a colloidal particle and a wall with femtonewton resolution. The equilibrium distribution of the particle-wall…

Moving the detection wavelength in vibrational sum-frequency generation (VSFG) spectroscopy to the near-infrared (> 700 nm) can potentially enable the study of molecular interfaces absorbing in the visible and give access to buried…

Optics · Physics 2024-05-10 Zsuzsanna Heiner , Valentin Petrov , Mark Mero

An integrated photonic circuit architecture to perform a modified-convolution operation based on the Discrete Fractional Fourier Transform (DFrFT) is introduced. This is accomplished by utilizing two nonuniformly-coupled waveguide lattices…

Optics · Physics 2025-02-25 Kevin Zelaya , Mohammad-Ali Miri

To reach the next frontier in multimode nonlinear optics, it is crucial to better understand the classical and quantum phenomena of systems with many interacting degrees of freedom -- both how they emerge and how they can be tailored to…

We use photothermal induced resonance (PTIR) imaging and spectroscopy, in resonant and non-resonant mode, to study the cytoplasmic membrane and surface of intact cells. Non-resonant PTIR images apparently provide rich details of the cell…

Applied Physics · Physics 2021-01-27 Luca Quaroni

Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system performance beyond the limit defined by its optical elements. The FPM technique applies a novel…

Optics · Physics 2014-05-02 Xiaoze Ou , Roarke Horstmeyer , Changhuei Yang , Guoan Zheng

The potential for improving the penetration depth of optical coherence tomography systems by using increasingly longer wavelength light sources has been known since the inception of the technique in the early 1990s. Nevertheless, the…

We experimentally demonstrate wide-band (>100 THz) frequency down-conversion of near-infrared (NIR) femtosecond-scale pulses from an Er:fiber laser to the mid-infrared (MIR) using four-wave-mixing (FWM) in photonic-chip silicon-nitride…

Rapid evolutions of microscopic fields govern the majority of elementary excitations in condensed matter and drive microelectronic currents at increasing frequencies. Beyond nominal "radio frequencies", however, access to local electric…

The spectral resolution of broadband Fourier-transform coherent anti-Stokes Raman spectroscopy is limited by the maximum optical path length difference that can be scanned within a short time in an interferometer. However, alternatives to…

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several…

Far-field optical imaging inevitably involves low-pass spatial filtering, limiting the resolution. Moreover, conventional imaging suppresses high spatial frequency components close to the cutoff, making them invisible under noise,…

Quantum Physics · Physics 2026-05-08 Li Gong , Aonan Zhang , Madhura Ghosh Dastidar , Alexander Duplinskii , A. I. Lvovsky

The Far-Infrared Surveyor (FIS) onboard the AKARI satellite has a spectroscopic capability provided by a Fourier transform spectrometer (FIS-FTS). FIS-FTS is the first space-borne imaging FTS dedicated to far-infrared astronomical…

Mid-infrared (mid-IR) spectroscopy offers unparalleled opportunities in sensing through chemically specific detection of molecular absorption fingerprints. Yet, its practical applications are limited by the weak light-matter interaction in…

Radio Frequency Interference (RFI) increasingly contaminates the radio astronomy spectrum, often exceeding astronomical signal amplitudes by 50-70 dB. Reliable detection and mitigation are therefore essential for studies of faint transient…

Instrumentation and Methods for Astrophysics · Physics 2026-05-08 Natalia A. Schmid , Sasanka Katreddi , Yechan Kweon

We use a microwave cavity to investigate the influence of a movable absorbing center on the wave function of an open quantum dot. Our study shows that the absorber acts as a position-selective probe, which may be used to suppress those wave…

Mesoscale and Nanoscale Physics · Physics 2010-06-07 Y. -H. Kim , M. Barth , U. Kuhl , H. -J. Stoeckmann , J. P. Bird

We report a direct demonstration of quantum-enhanced sensing in the Fourier domain by comparing single- and two-photon interference in a fiber-based interferometer under strictly identical noise conditions. The simultaneous acquisition of…

Infrared (IR) spectroscopy can be used as an important and effective tool for probing periodic networks of quantum wires or nanotubes (quantum crossbars, QCB) at finite frequencies far from the Luttinger liquid fixed point. Plasmon…

Strongly Correlated Electrons · Physics 2009-11-10 I. Kuzmenko , S. Gredeskul , K. Kikoin , Y. Avishai

The Infra-Red Imaging Spectrograph (IRIS) is one of the three first light instruments for the Thirty Meter Telescope (TMT) and is the only one to directly sample the diffraction limit. The instrument consists of a parallel imager and…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 Anna M. Moore , Brian J. Bauman , Elizabeth J. Barton , David Crampton , Alex Delacroix , James E. Larkin , Luc Simard , Ryuji Suzuki , Shelley A. Wright