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We propose a method for approximating solutions to optimization problems involving the global stability properties of parameter-dependent continuous-time autonomous dynamical systems. The method relies on an approximation of the…

Optimization and Control · Mathematics 2013-08-12 Péter Koltai , Alexander Volf

Signal transduction in living cells is vital to maintain life itself, where information transfer in noisy environment plays a significant role. In a rather different context, the recent intensive researches of "Maxwell's demon" - a feedback…

Statistical Mechanics · Physics 2015-06-30 Sosuke Ito , Takahiro Sagawa

Maxwell's demon is a special case of a feedback controlled system, where information gathered by measurement is utilized by driving a system along a thermodynamic process that depends on the measurement outcome. The demon illustrates that…

Statistical Mechanics · Physics 2015-06-16 Jordan M. Horowitz , Juan M. R. Parrondo

Biochemical signaling cascades transmit intracellular information while dissipating energy under nonequilibrium conditions. We model a cascade as a code string and apply information-entropy ideas to quantify an optimal transmission rate. A…

Molecular Networks · Quantitative Biology 2026-01-21 Tatsuaki Tsuruyama

Optimal transport theory, originally developed in the 18th century for civil engineering, has since become a powerful optimization framework across disciplines, from generative AI to cell biology. In physics, it has recently been shown to…

Statistical Mechanics · Physics 2025-12-02 Shingo Oikawa , Yohei Nakayama , Sosuke Ito , Takahiro Sagawa , Shoichi Toyabe

We establish a fundamental connection between score-based diffusion models and non-equilibrium thermodynamics by deriving performance limits based on entropy rates. Our main theoretical contribution is a lower bound on the negative…

Machine Learning · Computer Science 2025-10-08 Nathan X. Kodama , Michael Hinczewski

As a fundamental thermodynamic principle, speed limits reveal the lower bound of entropy production (EP) required for a system to transition from a given initial state to a final state. While various speed limits have been developed for…

Statistical Mechanics · Physics 2025-07-08 Sangyun Lee , Jae Sung Lee , Jong-Min Park

Thermodynamics serves as a universal means for studying physical systems from an energy perspective. In recent years, with the establishment of the field of stochastic and quantum thermodynamics, the ideas of thermodynamics have been…

Statistical Mechanics · Physics 2023-02-07 Tan Van Vu , Keiji Saito

The development of efficient artificial nanodevices poses challenges which are of fundamental and technological nature. Recent progress has been made in the context of finite-time thermodynamics. A central question in finite-time…

Statistical Mechanics · Physics 2014-03-18 Mario Einax

Motivated by entropic optimal transport, time reversal of Markov jump processes in $\mathbb{R}^n$ is investigated. Relying on an abstract integration by parts formula for the carr\'e du champ of a Markov process recently obtained by…

Probability · Mathematics 2022-09-05 Giovanni Conforti , Christian Léonard

We study a relationship between optimal transport theory and stochastic thermodynamics for the Fokker-Planck equation. We show that the lower bound on the entropy production is the action measured by the path length of the $L^2$-Wasserstein…

Statistical Mechanics · Physics 2021-11-02 Muka Nakazato , Sosuke Ito

We address the fundamental limits of learning unknown parameters of any stochastic process from time-series data, and discover exact closed-form expressions for how optimal inference scales with observation length. Given a parametrized…

Machine Learning · Computer Science 2023-10-09 Paul M. Riechers

We consider the framework of transfer-entropy-regularized Markov Decision Process (TERMDP) in which the weighted sum of the classical state-dependent cost and the transfer entropy from the state random process to the control random process…

Optimization and Control · Mathematics 2020-05-29 Takashi Tanaka , Henrik Sandberg , Mikael Skoglund

The Boltzmann distribution connects the energetics of an equilibrium system with its statistical properties, and it is desirable to have a similar principle for non-equilibrium systems. Here, we derive a variational principle for the…

Statistical Mechanics · Physics 2025-11-05 Atul Tanaji Mohite , Heiko Rieger

We study a dynamical system with time dependent Hamiltonian by numerical experiments so as to find a relation between thermodynamics and chaotic nature of the system. Excess information loss, defined newly based on Lyapunov analysis, is…

chao-dyn · Physics 2009-10-31 S. Sasa , T. S. Komatsu

Information flow between subsystems is a central concept in information thermodynamics, which provides the second-law-like inequalities for subsystems. This paper discusses the geometric decomposition of information flow, which was…

Statistical Mechanics · Physics 2025-12-30 Sosuke Ito , Yoh Maekawa , Ryuna Nagayama , Andreas Dechant , Kohei Yoshimura

In this theoretical study, we determine the maximum amount of work extractable in finite time by a demon performing continuous measurements on a quadratic Hamiltonian system subjected to thermal fluctuations, in terms of the information…

Statistical Mechanics · Physics 2014-10-21 Henrik Sandberg , Jean-Charles Delvenne , Nigel J. Newton , Sanjoy K. Mitter

The complete physical understanding of the optimization of the thermodynamic work still is an important open problem in stochastic thermodynamics. We address this issue using the Hamiltonian approach of linear response theory in finite time…

Statistical Mechanics · Physics 2022-08-18 Pierre Nazé , Sebastian Deffner , Marcus V. S. Bonança

Estimating entropy production from real observation data can be difficult due to finite resolution in both space and time and finite measurement statistics. We characterize the statistical error introduced by finite sample size and compare…

Statistical Mechanics · Physics 2025-04-09 Jonas H. Fritz , Benjamin Ertel , Udo Seifert

For a small system like a colloidal particle or a single biomolecule embedded in a heat bath, the optimal protocol of an external control parameter minimizes the mean work required to drive the system from one given equilibrium state to…

Statistical Mechanics · Physics 2009-11-13 Tim Schmiedl , Udo Seifert