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Overconfidence in deep learning models poses a significant risk in high-stakes medical imaging tasks, particularly in multi-label classification of chest X-rays, where multiple co-occurring pathologies must be detected simultaneously. This…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Yehudit Aperstein , Amit Tzahar , Alon Gottlib , Tal Verber , Ravit Shagan Damti , Alexander Apartsin

Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex…

Breast cancer remains a global challenge, causing over 1 million deaths globally in 2018. To achieve earlier breast cancer detection, screening x-ray mammography is recommended by health organizations worldwide and has been estimated to…

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

Breast cancer is one of the most common and dangerous cancers in women, while it can also afflict men. Breast cancer treatment and detection are greatly aided by the use of histopathological images since they contain sufficient phenotypic…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Md Ishtyaq Mahmud , Muntasir Mamun , Ahmed Abdelgawad

Breast Cancer is the most common cancer among women, which is also visible in men, and accounts for more than 1 in 10 new cancer diagnoses each year. It is also the second most common cause of women who die from cancer. Hence, it…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Kanan Mahammadli , Abdullah Burkan Bereketoglu , Ayse Gul Kabakci

Breast cancer is one of the leading causes of death for women worldwide. Early screening is essential for early identification, but the chance of survival declines as the cancer progresses into advanced stages. For this study, the most…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Fahad Ahmed , Reem Abdel-Salam , Leon Hamnett , Mary Adewunmi , Temitope Ayano

Breast cancer is a prevalent form of cancer among women, with over 1.5 million women being diagnosed each year. Unfortunately, the survival rates for breast cancer patients in certain third-world countries, like South Africa, are alarmingly…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Brennon Maistry , Absalom E. Ezugwu

Breast cancer has become one of the most prevalent cancers by which people all over the world are affected and is posed serious threats to human beings, in a particular woman. In order to provide effective treatment or prevention of this…

Image and Video Processing · Electrical Eng. & Systems 2021-07-15 Pouya Hallaj Zavareh , Atefeh Safayari , Hamidreza Bolhasani

Background: Breast density, as derived from mammographic images and defined by the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS), is one of the strongest risk factors for breast cancer. Breast ultrasound…

Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor…

Quantitative Methods · Quantitative Biology 2018-02-23 Valerio Maggio , Marco Chierici , Giuseppe Jurman , Cesare Furlanello

Deep learning-based diagnostic models often suffer performance drops due to distribution shifts between training (source) and test (target) domains. Collecting and labeling sufficient target domain data for model retraining represents an…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yaofei Duan , Yuhao Huang , Xin Yang , Luyi Han , Xinyu Xie , Zhiyuan Zhu , Ping He , Ka-Hou Chan , Ligang Cui , Sio-Kei Im , Dong Ni , Tao Tan

The clinical integration of deep learning models for brain tumor diagnosis in neuro-oncology is severely constrained by limited expert-annotated MRI data and substantial inter-institutional domain shift arising from variations in scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sapna Sachan , Amulya Kumar Mahto , Prashant Wagambar Patil

Deep learning models often achieve expert-level accuracy in medical image classification but suffer from a critical flaw: semantic incoherence. These high-confidence mistakes that are semantically incoherent (e.g., classifying a malignant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Abolfazl Mohammadi-Seif , Ricardo Baeza-Yates

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

Breast cancer is one of the leading causes of female mortality in the world. This can be reduced when diagnoses are performed at the early stages of progression. Further, the efficiency of the process can be significantly improved with…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Aravind Ravi

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Deep learning object detection algorithm has been widely used in medical image analysis. Currently all the object detection tasks are based on the data annotated with object classes and their bounding boxes. On the other hand, medical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Li Xiao , Cheng Zhu , Junjun Liu , Chunlong Luo , Peifang Liu , Yi Zhao