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In this work, we introduce an algorithmic approach to generate microvascular networks starting from larger vessels that can be reconstructed without noticeable segmentation errors. Contrary to larger vessels, the reconstruction of…
Four-dimensional (4D) Flow MRI can noninvasively measure cerebrovascular hemodynamics but remains underused clinically because current workflows rely on manual vessel segmentation and yield velocity fields sensitive to noise, artifacts, and…
Blood vessel segmentation and -tracing are essential tasks in many medical imaging applications. Although numerous methods exist, the prevailing segment-then-fix paradigm is fundamentally limited regarding its suitability for modeling the…
Delineating 3D blood vessels is essential for clinical diagnosis and treatment, however, is challenging due to complex structure variations and varied imaging conditions. Supervised deep learning has demonstrated its superior capacity in…
Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor development and an appealing target for therapy. Non-invasive, high-resolution, high sensitivity, quantitative 3D imaging techniques are required to correctly…
Stable diffusion, a generative model used in text-to-image synthesis, frequently encounters resolution-induced composition problems when generating images of varying sizes. This issue primarily stems from the model being trained on pairs of…
Four-dimensional Digital Subtraction Angiography (4D DSA) is a medical imaging technique that provides a series of 2D images captured at different stages and angles during the process of contrast agent filling blood vessels. It plays a…
Anisotropic Diffusion is widely used for noise reduction with simultaneous preservation of vascular structures in maximum intensity projected (MIP) angiograms. However, extension to minimum intensity projected (mIP) venograms in…
We present DeepVesselNet, an architecture tailored to the challenges faced when extracting vessel networks or trees and corresponding features in 3-D angiographic volumes using deep learning. We discuss the problems of low execution speed…
Our ability to produce human-scale bio-manufactured organs is critically limited by the need for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily complex geometries, designing and printing…
Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…
Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…
Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…
In recent years, the use of expressive surface visualizations in the representation of vascular structures has gained significant attention. These visualizations provide a comprehensive understanding of complex anatomical structures and are…
Cardiovascular disease (CVD) accounts for about half of non-communicable diseases. Vessel stenosis in the coronary artery is considered to be the major risk of CVD. Computed tomography angiography (CTA) is one of the widely used noninvasive…
Existing methods to reconstruct vascular structures from a computed tomography (CT) angiogram rely on injection of intravenous contrast to enhance the radio-density within the vessel lumen. However, pathological changes can be present in…
Text-to-3D is an emerging task that allows users to create 3D content with infinite possibilities. Existing works tackle the problem by optimizing a 3D representation with guidance from pre-trained diffusion models. An apparent drawback is…
The purpose of this study is to present a new semi-automated methodology for three-dimensional (3D) reconstruction of coronary arteries and their plaque morphology using Computed Tomography Angiography (CTA) images. The methodology is…
Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…
Optical Coherence Tomography Angiography (OCTA) has been increasingly used in the management of eye and systemic diseases in recent years. Manual or automatic analysis of blood vessel in 2D OCTA images (en face angiograms) is commonly used…