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Hyperparameters and learning algorithms for neuromorphic hardware are usually chosen by hand. In contrast, the hyperparameters and learning algorithms of networks of neurons in the brain, which they aim to emulate, have been optimized…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Thomas Bohnstingl , Franz Scherr , Christian Pehle , Karlheinz Meier , Wolfgang Maass

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

As the compute demands for machine learning and artificial intelligence applications continue to grow, neuromorphic hardware has been touted as a potential solution. New emerging devices like memristors, atomic switches, etc have shown…

Emerging Technologies · Computer Science 2020-09-24 Natesh Ganesh

Brain tumour segmentation plays a key role in computer-assisted surgery. Deep neural networks have increased the accuracy of automatic segmentation significantly, however these models tend to generalise poorly to different imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-09-06 Lucas Fidon , Wenqi Li , Luis C. Garcia-Peraza-Herrera , Jinendra Ekanayake , Neil Kitchen , Sebastien Ourselin , Tom Vercauteren

Chaotic dynamics have emerged as a versatile resource for neuromorphic and probabilistic computing, enabling high-dimensional nonlinear processing and classical analogues of quantum randomness. Exploiting chaos for computation requires…

Chaotic Dynamics · Physics 2026-05-20 Jungyoon Kim , Kyuho Kim , Kunwoo Park , Namkyoo Park , Sunkyu Yu

Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

Mechanics and biochemical signaling are both often deregulated in cancer, leading to cancer cell phenotypes that exhibit increased invasiveness, proliferation, and survival. The dynamics and interactions of cytoskeletal components control…

Biological Physics · Physics 2018-07-27 Fabian Spill , Chris Bakal , Michael Mak

I describe my path to unconventionality in my exploration of theoretical and applied aspects of computation towards revealing the algorithmic and reprogrammable properties and capabilities of the world, in particular related to applications…

General Literature · Computer Science 2017-06-28 Hector Zenil

A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-01-31 Gerard Briscoe , Philippe De Wilde

Variable selection for structured covariates lying on an underlying known graph is a problem motivated by practical applications, and has been a topic of increasing interest. However, most of the existing methods may not be scalable to high…

Methodology · Statistics 2016-04-27 Changgee Chang , Suprateek Kundu , Qi Long

Inspired by the human brain's structure and function, neuromorphic computing has emerged as a promising approach for developing energy-efficient and powerful computing systems. Neuromorphic computing offers significant processing speed and…

Emerging Technologies · Computer Science 2023-11-28 Jonathan Naoukin , Murat Isik , Karn Tiwari

Most research on adaptive decision-making takes a strategy-first approach, proposing a method of solving a problem and then examining whether it can be implemented in the brain and in what environments it succeeds. We present a method for…

Neural and Evolutionary Computing · Computer Science 2015-09-21 Peter Kvam , Joseph Cesario , Jory Schossau , Heather Eisthen , Arend Hintze

Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling can be a powerful tool to get a better understanding of cell…

Dynamical Systems · Mathematics 2022-03-24 Sabrina Schönfeld , Alican Ozkan , Laura Scarabosio , Marissa Nichole Rylander , Christina Kuttler

Cancer cells are widely known to be protected from apoptosis, which is a major hurdle to successful anti-cancer therapy. Over-expression of several anti-apoptotic proteins, or mutations in pro-apoptotic factors, has been recognized to…

Molecular Networks · Quantitative Biology 2010-09-14 Subhadip Raychaudhuri

Protein design has the potential to revolutionize biotechnology and medicine. While most efforts have focused on proteins with well-defined structures, increased recognition of the functional significance of intrinsically disordered…

Biomolecules · Quantitative Biology 2025-09-17 Giulio Tesei , Francesco Pesce , Kresten Lindorff-Larsen

Cancer progression is an evolutionary process that is driven by mutation and selection in a population of tumor cells. We discuss mathematical models of cancer progression, starting from traditional multistage theory. Each stage is…

Populations and Evolution · Quantitative Biology 2011-08-31 Moritz Gerstung , Niko Beerenwinkel

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

Over the last decade, artificial intelligence has found many applications areas in the society. As AI solutions have become more sophistication and the use cases grew, they highlighted the need to address performance and energy efficiency…

Emerging Technologies · Computer Science 2021-03-09 Eren Kurshan , Hai Li , Mingoo Seok , Yuan Xie

Software production research is quickly evolving on two parallel approaches: conventional and bio-inspired. The bio-inspired approaches are generally developed and presented as enhancements of the conventional ones. However the conventional…

Software Engineering · Computer Science 2019-09-12 Said Ghoul