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The development of quantum algorithms and their application to quantum chemistry has introduced new opportunities for solving complex molecular problems that are computationally infeasible for classical methods. In quantum chemistry, the…

Quantum Physics · Physics 2025-08-18 Fabio Tarocco , Davide Materia , Leonardo Ratini , Leonardo Guidoni

Variational quantum circuits are increasingly studied as continuous-function approximators, but quantum regression remains difficult to train when global losses, finite-shot stochasticity, and circuit-depth growth combine to produce weak or…

Machine Learning · Computer Science 2026-05-14 Qingyu Meng , Yangshuai Wang

Quantum operations on pure states can be fully represented by unitary matrices. Variational quantum circuits, also known as quantum neural networks, embed data and trainable parameters into gate-based operations and optimize the parameters…

Quantum Physics · Physics 2026-04-09 Basil Kyriacou , Mo Kordzanganeh , Maniraman Periyasamy , Alexey Melnikov

Variational quantum circuits characterise the state of a quantum system through the use of parameters that are optimised using classical optimisation procedures that typically rely on gradient information. The circuit-execution complexity…

Quantum Physics · Physics 2023-07-28 Sayantan Pramanik , Chaitanya Murti , M Girish Chandra

We investigate the performance of the variational quantum eigensolver (VQE) for the optimal flight gate assignment problem. This problem is a combinatorial optimization problem that aims at finding an optimal assignment of flights to the…

Barren plateaus (BP), characterized by exponentially vanishing gradients that hinder the training of variational quantum circuits (VQC), present a pervasive and critical challenge in applying variational quantum algorithms to real-world…

Quantum Physics · Physics 2025-01-24 Yipei Liu , Yuhong Song , Jinyang Li , Qiang Guan , Cheng-chang Lu , Youzuo Lin , Weiwen Jiang

Generative modeling is a flavor of machine learning with applications ranging from computer vision to chemical design. It is expected to be one of the techniques most suited to take advantage of the additional resources provided by…

Hybrid quantum-classical algorithms like the variational quantum eigensolver (VQE) show promise for quantum simulations on near-term quantum devices, but are often limited by complex objective functions and expensive optimization…

Quantum Physics · Physics 2026-01-21 Hang Zou , Martin Rahm , Anton Frisk Kockum , Simon Olsson

Training the Variational Quantum Eigensolver (VQE) is a task that requires substantial compute. We propose the use of concepts from transfer learning to considerably reduce the training time when solving similar problem instances. We…

Hybrid quantum-classical algorithms have been proposed as a potentially viable application of quantum computers. A particular example - the variational quantum eigensolver, or VQE - is designed to determine a global minimum in an energy…

Quantum Physics · Physics 2020-08-05 Alexey Uvarov , Jacob Biamonte , Dmitry Yudin

Optimizing the architecture of variational quantum circuits (VQCs) is crucial for advancing quantum computing (QC) towards practical applications. Current methods range from static ansatz design and evolutionary methods to machine learned…

In recent years, neural networks (NNs) have driven significant advances in machine learning. However, as tasks grow more complex, NNs often require large numbers of trainable parameters, which increases computational and energy demands.…

Variational Quantum Eigensolver (VQE) algorithms suffer from barren plateaus, where gradients vanish with system size and circuit depth. Although many mitigation strategies exist, their connection to convergence performance under different…

Quantum Physics · Physics 2025-12-15 Mostafa Atallah , Nouhaila Innan , Muhammad Kashif , Muhammad Shafique

Current structure optimization algorithms optimize the structure of quantum circuit from scratch for each new task of variational quantum algorithms (VQAs) without using any prior experience, which is inefficient and time-consuming.…

Quantum Physics · Physics 2022-04-12 Chuangtao Chen , Zhimin He , Shenggen Zheng , Yan Zhou , Haozhen Situ

Quantum algorithms offer a compelling new avenue for addressing difficult NP-complete optimization problems, such as the Generalized Assignment Problem (GAP). Given the operational constraints of contemporary Noisy Intermediate-Scale…

Quantum Physics · Physics 2025-11-05 Carlo Mastroianni , Francesco Plastina , Jacopo Settino , Andrea Vinci

This work studies the variational quantum eigensolver algorithm, designed to determine the ground state of a quantum mechanical system by combining classical and quantum hardware. Methods of reducing the number of required qubit…

Quantum Physics · Physics 2022-03-01 R. J. P. T. de Keijzer , V. E. Colussi , B. Škorić , S. J. J. M. F. Kokkelmans

Quantum machine learning (QML) has become a promising area for real world applications of quantum computers, but near-term methods and their scalability are still important research topics. In this context, we analyze the trainability and…

Quantum Physics · Physics 2025-05-21 Léo Monbroussou , Eliott Z. Mamon , Jonas Landman , Alex B. Grilo , Romain Kukla , Elham Kashefi

Variational quantum algorithms (VQAs) are promising methods to demonstrate quantum advantage on near-term devices as the required resources are divided between a quantum simulator and a classical optimizer. As such, designing a VQA which is…

Quantum Physics · Physics 2022-05-20 Yuhan Huang , Qingyu Li , Xiaokai Hou , Rebing Wu , Man-Hong Yung , Abolfazl Bayat , Xiaoting Wang

Variational quantum algorithms, which combine highly expressive parameterized quantum circuits (PQCs) and optimization techniques in machine learning, are one of the most promising applications of a near-term quantum computer. Despite their…

Quantum Physics · Physics 2024-02-07 Chae-Yeun Park , Nathan Killoran

Variational quantum algorithms (VQAs) are hybrid quantum-classical approaches used for tackling a wide range of problems on noisy intermediate-scale quantum (NISQ) devices. Testing these algorithms on relevant hardware is crucial to…

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