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The microbiome constitutes a complex microbial ecology of interacting components that regulates important pathways in the host. Measurements of microbial abundances are key to learning the intricate network of interactions amongst microbes.…

Methodology · Statistics 2024-06-17 Veronica Vinciotti , Ernst Wit , Francisco Richter

Micro-swimmers such as bacteria perform random walks known as run-and-tumbles to move up chemo-attractant gradients and as a result aggregate with others. It is also known that such micro-swimmers can self-organize into macroscopic patterns…

Biological Physics · Physics 2016-08-31 Enkeleida Lushi

Collective behavior of bacterial colonies plays critical roles in adaptability, survivability, biofilm expansion and infection. We employ an individual-based model of an interstitial biofilm to study emergent pattern formation based on the…

Adaptation and Self-Organizing Systems · Physics 2017-02-01 Cameron Zachreson , Christian Wolff , Cynthia B. Whitchurch , Milos Toth

Segregation of populations is a key question in evolution theory. One important aspect is the relation between spatial organization and the population's composition. Here we study a specific example -- sectors in expanding bacterial…

Condensed Matter · Physics 2009-10-31 Ido Golding , Inon Cohen , Eshel Ben-Jacob

Colonies of rod-shaped bacteria constitute a system of colloidal active matter with nematic properties. As a single initial bacterium multiplies through repeated divisions, the resulting colony quickly loses long-range orientational order,…

Collective motion is a phenomenon observed across length scales in nature, from bacterial swarming and tissue migration to the flocking of animals. The mechanisms underlying this behavior vary significantly depending on the biological…

Soft Condensed Matter · Physics 2025-01-15 Urvi Mahendra Bora , Mohd Suhail Rizvi

Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth. The use of spatial light modulators could help to elucidate the mechanisms of…

The evolutionary success of bacteria lies in their ability to form complex surface-associated communities in diverse biophysical settings. However, it remains poorly understood how compliance of soft surfaces, measured in terms of their…

Soft Condensed Matter · Physics 2025-08-05 Garima Rani , Anupam Sengupta

Understanding the relationship between complexity and stability in large dynamical systems -- such as ecosystems -- remains a key open question in complexity theory which has inspired a rich body of work developed over more than fifty…

Populations and Evolution · Quantitative Biology 2021-07-14 Yvonne Krumbeck , Qian Yang , George W. A. Constable , Tim Rogers

We introduce various models for cellulose bio-degradation by micro-organisms. Those models rely on complex chemical mechanisms, involve the structure of the cellulose chains and are allowed to depend on the phenotypical traits of the…

Dynamical Systems · Mathematics 2020-11-09 Pierre-Emmanuel Jabin , Alexey Miroshnikov , Robin Young

Bacteria can adjust the structure of colonies and biofilms to enhance their survival rate under external stress. Here, we explore the link between bacterial interaction forces and colony structure. We show that the activity of extracellular…

Shape anisotropy of individual building blocks plays a crucial role in creating exotic structures and controlling phase behavior in equilibrium systems. We present a combined experimental and simulation study in which we used light-driven…

Soft Condensed Matter · Physics 2026-05-05 Yogesh Shelke , Anpuj Nair S , Hanumantha Rao Vutukuri

Turbulence is ubiquitous, from oceanic currents to small-scale biological and quantum systems. Self-sustained turbulent motion in microbial suspensions presents an intriguing example of collective dynamical behavior amongst the simplest…

From the formation of animal flocks to the emergence of coordinate motion in bacterial swarms, at all scales populations of motile organisms display coherent collective motion. This consistent behavior strongly contrasts with the difference…

Soft Condensed Matter · Physics 2013-11-11 Antoine Bricard , Jean-Baptiste Caussin , Nicolas Desreumaux , Olivier Dauchot , Denis Bartolo

Microbial communities routinely have several alternative stable states observed for the same environmental parameters. Sudden and irreversible transitions between these states make external manipulation of these systems more complicated. To…

Populations and Evolution · Quantitative Biology 2018-10-12 Veronika Dubinkina , Yulia Fridman , Parth Pandey , Sergei Maslov

The large-scale collective behavior of biological systems can be characterized by macroscopic transport, which arises from the non-equilibrium microscopic interactions among individual constituents. A prominent example is the formation of…

Statistical Mechanics · Physics 2025-07-29 Subhadip Chakraborti , Vasily Zaburdaev

Dormancy is an essential strategy for microorganisms to cope with environmental stress. However, global ecosystem models typically ignore microbial dormancy, resulting in major model uncertainties. To facilitate the consideration of…

Quantitative Methods · Quantitative Biology 2014-02-20 Gangsheng Wang , Melanie A. Mayes , Lianhong Gu , Christopher W. Schadt

We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

Soft Condensed Matter · Physics 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

Diverse processes--e.g. bioremediation, biofertilization, and microbial drug delivery--rely on bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore-scale confinement alters bacterial motility is unknown…

Soft Condensed Matter · Physics 2019-05-09 Tapomoy Bhattacharjee , Sujit S. Datta

The twisting and writhing of a cell body and associated mechanical stresses is an underappreciated constraint on microbial self-propulsion. Multi-flagellated bacteria can even buckle and writhe under their own activity as they swim through…

Soft Condensed Matter · Physics 2023-09-25 Wilson Lough , Douglas B. Weibel , Saverio E. Spagnolie
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