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Motility is an essential factor for an organism's survival and diversification. With the advent of novel single-cell technologies, analytical frameworks and theoretical methods, we can begin to probe the complex lives of microscopic motile…

Microbial communities routinely have several possible species compositions or community states observed for the same environmental parameters. Changes in these parameters can trigger abrupt and persistent transitions (regime shifts) between…

Populations and Evolution · Quantitative Biology 2019-07-03 Veronika Dubinkina , Yulia Fridman , Parth Pratim Pandey , Sergei Maslov

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

Biological Physics · Physics 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Bacterial swarming is a rapid mass-migration, in which thousands of cells spread collectively to colonize a surface. Physically, swarming is a natural example of active particles that use energy to generate motion. Accordingly,…

Soft Condensed Matter · Physics 2019-11-14 Avraham Be`er , Bella Ilkanaiv , Renan Gross , Daniel B. Kearns , Sebastian Heidenreich , Markus Bär , Gil Ariel

In this paper we present a hydrodynamic approach to describe the motion of migrating bacteria as a special class of self-propelled systems. Analytical and numerical calculations has been performed to study the behavior of our model in the…

Soft Condensed Matter · Physics 2015-06-25 Zoltan Csahok , Andras Czirok

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can…

Populations and Evolution · Quantitative Biology 2023-11-16 Lluís Hernández-Navarro , Matthew Asker , Alastair M. Rucklidge , Mauro Mobilia

Motile cells often explore natural environments characterized by a high degree of structural complexity. Moreover cell motility is also intrinsically noisy due to spontaneous random reorientation and speed fluctuations. This interplay of…

The diffusion of active microscopic organisms in complex environments plays an important role in a wide range of biological phenomena from cell colony growth to single organism transport. Here, we investigate theoretically and…

Fluid Dynamics · Physics 2018-01-16 Juan L. Aragones , Shahrzad Yazdi , Alfredo Alexander-Katz

Bacteria regulate their motility through a variety of mechanisms, including quorum sensing (QS) and other density-dependent responses mediated by diffusible signals. While nonlinear density-dependent motility is well known in active-matter…

Populations and Evolution · Quantitative Biology 2026-01-21 Mattia Mattei , David Soriano-Paños , Alex Arenas

Microbial populations in the natural environment are likely to experience growth conditions very different from those of a typical laboratory xperiment. In particular, removal rates of biomass and substrate are unlikely to be balanced under…

Populations and Evolution · Quantitative Biology 2015-05-18 Bhavin S. Khatri , Andrew Free , Rosalind J. Allen

Adaptive control in biological systems, such as intestinal immunity, remains poorly understood despite detailed knowledge of underlying regulatory networks. We propose an alternative framework based on stochastic martingale turnover, in…

Adaptation and Self-Organizing Systems · Physics 2026-05-01 Tomoyuki Yamaguchi

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

Cell Behavior · Quantitative Biology 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

Microbial ecosystems are remarkably diverse, stable, and often consist of a balanced mixture of core and peripheral species. Here we propose a conceptual model exhibiting all these emergent properties in quantitative agreement with real…

Populations and Evolution · Quantitative Biology 2018-04-18 Akshit Goyal , Sergei Maslov

The metabolic activity of microbes has played an essential role in the evolution and persistence of life on Earth. Microbial metabolism plays a primary role in the flow of carbon, nitrogen and other elements through the biosphere on a…

Populations and Evolution · Quantitative Biology 2022-01-20 Chandana Gopalakrishnappa , Karna Gowda , Kaumudi Prabhakara , Seppe Kuehn

Bioconvection, a phenomenon arising from the collective motion of motile microorganisms, plays a crucial role in shaping microbial distributions, fluid dynamics, and bloom formation in aquatic environments. While extensive research has…

Biological Physics · Physics 2025-04-15 Samarendu Biswas , Sachidananda Mahato , Jayabrata Dhar

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…

Physics and Society · Physics 2019-02-07 Alberto Aleta , Andreia N. S. Hisi , Sandro Meloni , Chiara Poletto , Vittoria Colizza , Yamir Moreno

Biased locomotion is a common feature of microorganisms, but little is known about its impact on self-organisation. Inspired by recent experiments showing a transition to large-scale flows, we study theoretically the dynamics of…

Soft Condensed Matter · Physics 2023-12-07 Albane Théry , Alexander Chamolly , Eric Lauga