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Related papers: SynLlama: Generating Synthesizable Molecules and T…

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Training models on synthetic data has emerged as an increasingly important strategy for improving the performance of generative AI. This approach is particularly helpful for large multimodal models (LMMs) due to the relative scarcity of…

Artificial Intelligence · Computer Science 2026-01-13 Gabriela Ben Melech Stan , Estelle Aflalo , Avinash Madasu , Vasudev Lal , Phillip Howard

Large language models (LLMs) have emerged as powerful tools in chemistry, significantly impacting molecule design, property prediction, and synthesis optimization. This review highlights LLM capabilities in these domains and their potential…

Machine Learning · Computer Science 2024-11-18 Mayk Caldas Ramos , Christopher J. Collison , Andrew D. White

This paper addresses fine-tuning Large Language Models (LLMs) for function calling tasks when real user interaction data is unavailable. In digital content creation tools, where users express their needs through natural language queries…

As large language models (LLMs) advance, their ability to perform in-context learning and few-shot language generation has improved significantly. This has spurred using LLMs to produce high-quality synthetic data to enhance the performance…

Computation and Language · Computer Science 2025-02-18 Jiyuan Ren , Zhaocheng Du , Zhihao Wen , Qinglin Jia , Sunhao Dai , Chuhan Wu , Zhenhua Dong

Large Language Models (LLMs) employ three popular training approaches: Masked Language Models (MLM), Causal Language Models (CLM), and Sequence-to-Sequence Models (seq2seq). However, each approach has its strengths and limitations, and…

Machine Learning · Computer Science 2025-02-18 Xuefeng Liu , Songhao Jiang , Bo Li , Rick Stevens

We present LL3M, a multi-agent system that leverages pretrained large language models (LLMs) to generate 3D assets by writing interpretable Python code in Blender. We break away from the typical generative approach that learns from a…

Graphics · Computer Science 2025-08-12 Sining Lu , Guan Chen , Nam Anh Dinh , Itai Lang , Ari Holtzman , Rana Hanocka

Understanding data visualizations like charts and plots requires reasoning about both visual elements and numerics. Although strong in extractive questions, current chart visual question answering (chart VQA) models suffer on complex…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Zhuowan Li , Bhavan Jasani , Peng Tang , Shabnam Ghadar

Due to the advantages of hypergraphs in modeling high-order relationships in complex systems, they have been applied to higher-order clustering, hypergraph neural networks and computer vision. These applications rely heavily on access to…

Social and Information Networks · Computer Science 2025-10-15 Bingqiao Gu , Jiale Zeng , Xingqin Qi , Dong Li

Large language models (LLMs) have great potential for synthetic data generation. This work shows that useful data can be synthetically generated even for tasks that cannot be solved directly by LLMs: for problems with structured outputs, it…

Computation and Language · Computer Science 2023-10-31 Martin Josifoski , Marija Sakota , Maxime Peyrard , Robert West

Large language models (LLMs) have become a dominant and important tool for NLP researchers in a wide range of tasks. Today, many researchers use LLMs in synthetic data generation, task evaluation, fine-tuning, distillation, and other…

Computation and Language · Computer Science 2024-05-29 Ajay Patel , Colin Raffel , Chris Callison-Burch

While automated chemical tools excel at specific tasks, they have struggled to capture the strategic thinking that characterizes expert chemical reasoning. Here we demonstrate that large language models (LLMs) can serve as powerful tools…

Artificial Intelligence · Computer Science 2025-07-25 Andres M Bran , Theo A Neukomm , Daniel P Armstrong , Zlatko Jončev , Philippe Schwaller

Deep generative models are able to suggest new organic molecules by generating strings, trees, and graphs representing their structure. While such models allow one to generate molecules with desirable properties, they give no guarantees…

Machine Learning · Computer Science 2019-12-05 John Bradshaw , Brooks Paige , Matt J. Kusner , Marwin H. S. Segler , José Miguel Hernández-Lobato

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

Biomolecules · Quantitative Biology 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

The study of biological materials and bio-inspired materials science is well established; however, surprisingly little knowledge has been systematically translated to engineering solutions. To accelerate discovery and guide insights, an…

Materials Science · Physics 2023-12-12 Rachel K. Luu , Markus J. Buehler

This work explores expanding the capabilities of large language models (LLMs) pretrained on text to generate 3D meshes within a unified model. This offers key advantages of (1) leveraging spatial knowledge already embedded in LLMs, derived…

Machine Learning · Computer Science 2024-11-15 Zhengyi Wang , Jonathan Lorraine , Yikai Wang , Hang Su , Jun Zhu , Sanja Fidler , Xiaohui Zeng

Understanding molecules is key to understanding organisms and driving advances in drug discovery, requiring interdisciplinary knowledge across chemistry and biology. Although large molecular language models have achieved notable success in…

Machine Learning · Computer Science 2025-10-03 Dongki Kim , Wonbin Lee , Sung Ju Hwang

Large Language Models demonstrate substantial promise for advancing scientific discovery, yet their deployment in disciplines demanding factual precision and specialized domain constraints presents significant challenges. Within molecular…

Machine Learning · Computer Science 2026-02-23 Malikussaid , Hilal Hudan Nuha , Isman Kurniawan

Training large language models (LLMs) with synthetic reasoning data has become a popular approach to enhancing their reasoning capabilities, while a key factor influencing the effectiveness of this paradigm is the quality of the generated…

Artificial Intelligence · Computer Science 2026-03-24 Zhuojie Yang , Wentao Wan , Keze Wang

Synthetic training data generation with Large Language Models (LLMs) like Google's Gemma and OpenAI's GPT offer a promising solution to the challenge of obtaining large, labeled datasets for training classifiers. When rapid model deployment…

This paper presents DreamLLM, a learning framework that first achieves versatile Multimodal Large Language Models (MLLMs) empowered with frequently overlooked synergy between multimodal comprehension and creation. DreamLLM operates on two…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Runpei Dong , Chunrui Han , Yuang Peng , Zekun Qi , Zheng Ge , Jinrong Yang , Liang Zhao , Jianjian Sun , Hongyu Zhou , Haoran Wei , Xiangwen Kong , Xiangyu Zhang , Kaisheng Ma , Li Yi
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