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Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Image segmentation is a fundamental task in the field of imaging and vision. Supervised deep learning for segmentation has achieved unparalleled success when sufficient training data with annotated labels are available. However, annotation…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Hongrun Zhang , Liam Burrows , Yanda Meng , Declan Sculthorpe , Abhik Mukherjee , Sarah E Coupland , Ke Chen , Yalin Zheng

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Khang Le , Anh Mai Vu , Thi Kim Trang Vo , Ha Thach , Ngoc Bui Lam Quang , Thanh-Huy Nguyen , Minh H. N. Le , Zhu Han , Chandra Mohan , Hien Van Nguyen

Most medical image lesion segmentation methods rely on hand-crafted accurate annotations of the original image for supervised learning. Recently, a series of weakly supervised or unsupervised methods have been proposed to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Jiawei Chen , Dingkang Yang , Yuxuan Lei , Lihua Zhang

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Though image-level weakly supervised semantic segmentation (WSSS) has achieved great progress with Class Activation Maps (CAMs) as the cornerstone, the large supervision gap between classification and segmentation still hampers the model to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Ye Du , Zehua Fu , Qingjie Liu , Yunhong Wang

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Existing weakly-supervised semantic segmentation methods using image-level annotations typically rely on initial responses to locate object regions. However, such response maps generated by the classification network usually focus on…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Yu-Ting Chang , Qiaosong Wang , Wei-Chih Hung , Robinson Piramuthu , Yi-Hsuan Tsai , Ming-Hsuan Yang

Reliable classification and detection of certain medical conditions, in images, with state-of-the-art semantic segmentation networks, require vast amounts of pixel-wise annotation. However, the public availability of such datasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Erik Ostrowski , Bharath Srinivas Prabakaran , Muhammad Shafique

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Medical image segmentation is one of the domains where sufficient annotated data is not available. This necessitates the application of low-data frameworks like few-shot learning. Contemporary prototype-based frameworks often do not account…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Siladittya Manna , Saumik Bhattacharya , Umapada Pal

Weakly-Supervised Semantic Segmentation (WSSS) aims to train segmentation models using image data with only image-level supervision. Since precise pixel-level annotations are not accessible, existing methods typically focus on producing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Ci-Siang Lin , Chien-Yi Wang , Yu-Chiang Frank Wang , Min-Hung Chen

Classification networks can be used to localize and segment objects in images by means of class activation maps (CAMs). However, without pixel-level annotations, classification networks are known to (1) mainly focus on discriminative…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Arvi Jonnarth , Michael Felsberg

Weakly-supervised medical image segmentation is a challenging task that aims to reduce the annotation cost while keep the segmentation performance. In this paper, we present a novel framework, SimTxtSeg, that leverages simple text cues to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Yuxin Xie , Tao Zhou , Yi Zhou , Geng Chen

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao

As research interests in medical image analysis become increasingly fine-grained, the cost for extensive annotation also rises. One feasible way to reduce the cost is to annotate with coarse-grained superclass labels while using limited…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Linrui Dai , Wenhui Lei , Xiaofan Zhang
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