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The novel coronavirus disease 2019 (COVID-19) characterized by atypical pneumonia has caused millions of deaths worldwide. Automatically segmenting lesions from chest Computed Tomography (CT) is a promising way to assist doctors in COVID-19…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Yanwen Li , Luyang Luo , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Due to the high stakes in medical decision-making, there is a compelling demand for interpretable deep learning methods in medical image analysis. Concept Bottleneck Models (CBM) have emerged as an active interpretable framework…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yibo Gao , Zheyao Gao , Xin Gao , Yuanye Liu , Bomin Wang , Xiahai Zhuang

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Vandan Gorade , Sparsh Mittal , Debesh Jha , Rekha Singhal , Ulas Bagci

Recently, deep learning has been adopted to the glaucoma classification task with performance comparable to that of human experts. However, a well trained deep learning model demands a large quantity of properly labeled data, which is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Junde Wu , Shuang Yu , Wenting Chen , Kai Ma , Rao Fu , Hanruo Liu , Xiaoguang Di , Yefeng Zheng

Clinicians in the frontline need to assess quickly whether a patient with symptoms indeed has COVID-19 or not. The difficulty of this task is exacerbated in low resource settings that may not have access to biotechnology tests. Furthermore,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-23 Ali H. Al-Timemy , Rami N. Khushaba , Zahraa M. Mosa , Javier Escudero

The COVID-19 pandemic exposed critical limitations in diagnostic workflows: RT-PCR tests suffer from slow turnaround times and high false-negative rates, while CT-based screening offers faster complementary diagnosis but requires expert…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Aadit Nilay , Bhavesh Thapar , Anant Agrawal , Mohammad Nayeem Teli

One of the common issues in clinical decision-making is the presence of uncertainty, which often arises due to ambiguity in radiology reports, which often reflect genuine diagnostic uncertainty or limitations of automated label extraction…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Antik Aich Roy , Ujjwal Bhattacharya

Deep learning has shown promising contributions in medical image segmentation with powerful learning and feature representation abilities. However, it has limitations for reasoning with and combining imperfect (imprecise, uncertain, and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Ling Huang

Deep learning classification models for medical image analysis often perform well on data from scanners that were used during training. However, when these models are applied to data from different vendors, their performance tends to drop…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Coen de Vente , Bram van Ginneken , Carel B. Hoyng , Caroline C. W. Klaver , Clara I. Sánchez

Deep neural networks have achieved remarkable success in computer vision; however, their black-box nature in decision-making limits interpretability and trust, particularly in safety-critical applications. Interpretability is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ran Eisenberg , Amit Rozner , Ethan Fetaya , Ofir Lindenbaum

Intelligent analysis of medical imaging plays a crucial role in assisting clinical diagnosis, especially for identifying subtle pathological features. This paper introduces a novel multi-branch ConvNeXt architecture designed specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Irash Perera , Uthayasanker Thayasivam

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Medical image interpretation using deep learning has shown promise but often requires extensive expert-annotated datasets. To reduce this annotation burden, we develop an Image-Graph Contrastive Learning framework that pairs chest X-rays…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Sameer Khanna , Daniel Michael , Marinka Zitnik , Pranav Rajpurkar

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Hung Q. Vo , Pengyu Yuan , Tiancheng He , Stephen T. C. Wong , Hien V. Nguyen

The quality of diabetic retinopathy (DR) screening relies on the ability to correctly grade severity; however, many deep-learning (DL) classifiers cannot be easily interpreted in the clinical context. This study presents a methodology that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba , Sule Yildirim Yayilgan , Sarang Shaikh

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

The outbreak of novel coronavirus disease (COVID- 19) has claimed millions of lives and has affected all aspects of human life. This paper focuses on the application of deep learning (DL) models to medical imaging and drug discovery for…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal , V. B. Surya Prasath
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