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Clinical MRI frequently acquires anisotropic volumes with high in-plane resolution and low through-plane resolution to reduce acquisition time. Multiple orientations are therefore acquired to provide complementary anatomical information.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-25 Heejong Kim , Abhishek Thanki , Roel van Herten , Daniel Margolis , Mert R Sabuncu

The most sophisticated existing methods to generate 3D isotropic super-resolution (SR) from non-isotropic electron microscopy (EM) are based on learned dictionaries. Unfortunately, none of the existing methods generate practically…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Larissa Heinrich , John A. Bogovic , Stephan Saalfeld

Computed tomography (CT) is one of the most widely used non-invasive imaging modalities for medical diagnosis. In clinical practice, CT images are usually acquired with large slice thicknesses due to the high cost of memory storage and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Kwang-Hyun Uhm , Hyunjun Cho , Sung-Hoo Hong , Seung-Won Jung

In motion-robust magnetic resonance imaging (MRI), slice-to-volume reconstruction is critical for recovering anatomically consistent 3D brain volumes from 2D slices, especially under accelerated acquisitions or patient motion. However, this…

Image and Video Processing · Electrical Eng. & Systems 2026-03-25 Zhenxuan Zhang , Lipei Zhang , Yanqi Cheng , Zi Wang , Fanwen Wang , Haosen Zhang , Yue Yang , Yinzhe Wu , Jiahao Huang , Angelica I Aviles-Rivero , Zhifan Gao , Guang Yang , Peter J. Lally

Anisotropic low-resolution (LR) magnetic resonance (MR) images are fast to obtain but hinder automated processing. We propose to use denoising diffusion probabilistic models (DDPMs) to super-resolve these 2D-acquired LR MR slices. This…

Image and Video Processing · Electrical Eng. & Systems 2023-12-08 Zejun Wu , Samuel W. Remedios , Blake E. Dewey , Aaron Carass , Jerry L. Prince

The inability to acquire clean high-resolution (HR) electron microscopy (EM) images over a large brain tissue volume hampers many neuroscience studies. To address this challenge, we propose a deep-learning-based image super-resolution (SR)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Mohammad Khateri , Morteza Ghahremani , Alejandra Sierra , Jussi Tohka

Magnetic resonance imaging (MRI) super-resolution (SR) methods that computationally enhance low-resolution acquisitions to approximate high-resolution quality offer a compelling alternative to expensive high-field scanners. In this work we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Hendrik Chiche , Ludovic Corcos , Logan Rouge

Computed tomography (CT) samples with pathological annotations are difficult to obtain. As a result, the computer-aided diagnosis (CAD) algorithms are trained on small datasets (e.g., LIDC-IDRI with 1,018 samples), limiting their accuracies…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Penghua Zhai , Enwei Zhu , Baolian Qi , Xin Wei , Jinpeng Li

Neuropathological analyses benefit from spatially precise volumetric reconstructions that enhance anatomical delineation and improve morphometric accuracy. Our prior work has shown the feasibility of reconstructing 3D brain volumes from 2D…

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Although high resolution isotropic 3D medical images are desired in clinical practice, their acquisition is not always feasible. Instead, lower resolution images are upsampled to higher resolution using conventional interpolation methods.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Jörg Sander , Bob D. de Vos , Ivana Išgum

Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Hyoungjun Park , Myeongsu Na , Bumju Kim , Soohyun Park , Ki Hean Kim , Sunghoe Chang , Jong Chul Ye

To date, the most common approach for radiology deep learning pipelines is the use of end-to-end 3D networks based on models pre-trained on other tasks, followed by fine-tuning on the task at hand. In contrast, adjacent medical fields such…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Marta Ligero , Tim Lenz , Georg Wölflein , Omar S. M. El Nahhas , Daniel Truhn , Jakob Nikolas Kather

Multi-contrast MRI methods acquire multiple images with different contrast weightings, which are used for the differentiation of the tissue types or quantitative mapping. However, the scan time needed to acquire multiple contrasts is…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Yan Chen , Jyothi Rikhab Chand , Steven R. Kecskemeti , James H. Holmes , Mathews Jacob

Magnetic Resonance Imaging (MRI) represents an important diagnostic modality; however, its inherently slow acquisition process poses challenges in obtaining fully-sampled $k$-space data under motion. In the absence of fully-sampled…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 George Yiasemis , Nikita Moriakov , Clara I. Sánchez , Jan-Jakob Sonke , Jonas Teuwen

High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D…

Image and Video Processing · Electrical Eng. & Systems 2024-03-20 Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Juan Eugenio Iglesias

Deep learning-based dMRI super-resolution methods can effectively enhance image resolution by leveraging the learning capabilities of neural networks on large datasets. However, these methods tend to learn a fixed scale mapping between…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Ruoyou Wu , Jian Cheng , Cheng Li , Juan Zou , Jing Yang , Wenxin Fan , Yong Liang , Shanshan Wang

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Cheng Jiang , Alexander Gedeon , Yiwei Lyu , Eric Landgraf , Yufeng Zhang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Honglak Lee , Todd Hollon

In Magnetic Resonance Imaging (MRI), image acquisitions are often undersampled in the measurement domain to accelerate the scanning process, at the expense of image quality. However, image quality is a crucial factor that influences the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Mevan Ekanayake , Zhifeng Chen , Mehrtash Harandi , Gary Egan , Zhaolin Chen

Automatic and accurate tumor segmentation on medical images is in high demand to assist physicians with diagnosis and treatment. However, it is difficult to obtain massive amounts of annotated training data required by the deep-learning…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Xiaoman Zhang , Shixiang Feng , Yuhang Zhou , Ya Zhang , Yanfeng Wang