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Principal component analysis (PCA) is a classical and ubiquitous method for reducing data dimensionality, but it is suboptimal for heterogeneous data that are increasingly common in modern applications. PCA treats all samples uniformly so…

Statistics Theory · Mathematics 2021-12-02 David Hong , Kyle Gilman , Laura Balzano , Jeffrey A. Fessler

Motivation: Recent advances in technology for brain imaging and high-throughput genotyping have motivated studies examining the influence of genetic variation on brain structure. Wang et al. (Bioinformatics, 2012) have developed an approach…

Methodology · Statistics 2016-10-18 Keelin Greenlaw , Elena Szefer , Jinko Graham , Mary Lesperance , Farouk S. Nathoo

Sleep change is commonly reported in Alzheimer's disease (AD) patients and their brain wave studies show decrease in dreaming and non-dreaming stages. Although sleep disturbance is generally considered as a consequence of AD, it might also…

Neurons and Cognition · Quantitative Biology 2020-06-26 Yejin Kim , Xiaoqian Jiang , Luyao Chen , Xiaojin Li , Licong Cui

Wi-Fi channel state information (CSI) has become a promising solution for non-invasive breathing and body motion monitoring during sleep. Sleep disorders of apnea and periodic limb movement disorder (PLMD) are often unconscious and fatal.…

Signal Processing · Electrical Eng. & Systems 2023-04-14 Chi-Che Chang , An-Hung Hsiao , Li-Hsiang Shen , Kai-Ten Feng , Chia-Yu Chen

Oversampled adaptive sensing (OAS) is a Bayesian framework recently proposed for effective sensing of structured signals in a time-limited setting. In contrast to the conventional blind oversampling, OAS uses the prior information on the…

Information Theory · Computer Science 2021-03-01 Ali Bereyhi , Saba Asaad , Ralf R. Müller

State-of-the-art automatic sleep staging methods have already demonstrated comparable reliability and superior time efficiency to manual sleep staging. However, fully automatic black-box solutions are difficult to adapt into clinical…

Automatic sleep staging is a challenging problem and state-of-the-art algorithms have not yet reached satisfactory performance to be used instead of manual scoring by a sleep technician. Much research has been done to find good feature…

Machine Learning · Computer Science 2018-05-15 Martin Längkvist , Amy Loutfi

Sleep constitutes a key indicator of human health, performance, and quality of life. Sleep deprivation has long been related to the onset, development, and worsening of several mental and metabolic disorders, constituting an essential…

Signal Processing · Electrical Eng. & Systems 2023-01-25 María Martínez-García , Fernando Moreno-Pino , Pablo M. Olmos , Antonio Artés-Rodríguez

This paper proposes a new approach to identifying patients with insomnia using a single EEG channel, without the need for sleep stage annotation. Data preprocessing, feature extraction, feature selection, and classification techniques are…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Chan-Yun Yang , Nilantha Premakumara , Hooman Samani , Chinthaka Premachandra

Objectives: The study aims to investigate the relationship between insomnia and response time. Additionally, it aims to develop a machine learning model to predict the presence of insomnia in participants using response time data. Methods:…

Machine Learning · Computer Science 2023-10-16 Zhao Su , Rongxun Liu , Keyin Zhou , Xinru Wei , Ning Wang , Zexin Lin , Yuanchen Xie , Jie Wang , Fei Wang , Shenzhong Zhang , Xizhe Zhang

We revisit the classical problem of Bayesian ensembles and address the challenge of learning optimal combinations of Bayesian models in an online, continual learning setting. To this end, we reinterpret existing approaches such as Bayesian…

Machine Learning · Computer Science 2026-01-26 Daniel Waxman , Fernando Llorente , Petar M. Djurić

Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…

Over the years, several approaches have tried to tackle the problem of performing an automatic scoring of the sleeping stages. Although any polysomnography usually collects over a dozen of different signals, this particular problem has been…

Machine Learning · Computer Science 2021-07-26 Enrique Fernandez-Blanco , Carlos Fernandez-Lozano , Alejandro Pazos , Daniel Rivero

Knee osteoarthritis (OA) assessment involves a natural but often underused label hierarchy: a coarse binary OA decision and a fine-grained Kellgren--Lawrence (KL) severity grade. Existing deep learning studies commonly treat these targets…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Tongxu Zhang

The classification of sleep stages is a pivotal aspect of diagnosing sleep disorders and evaluating sleep quality. However, the conventional manual scoring process, conducted by clinicians, is time-consuming and prone to human bias. Recent…

Human-Computer Interaction · Computer Science 2024-05-14 Cheol-Hui Lee , Hakseung Kim , Hyun-jee Han , Min-Kyung Jung , Byung C. Yoon , Dong-Joo Kim

In the field of operational modal analysis (OMA), obtained modal information is frequently used to assess the current state of aerospace, mechanical, offshore and civil structures. However, the stochasticity of operational systems and the…

Machine Learning · Statistics 2025-07-04 Brandon J. O'Connell , Max D. Champneys , Timothy J. Rogers

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

Methodology · Statistics 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi

During psychiatric assessment, clinicians observe not only what patients report, but important nonverbal signs such as tone, speech rate, fluency, responsiveness, and body language. Weighing and integrating these different information…

Machine Learning · Computer Science 2025-12-19 Agnes Norbury , George Fairs , Alexandra L. Georgescu , Matthew M. Nour , Emilia Molimpakis , Stefano Goria

Chronic diseases often progress differently across patients. Rather than randomly varying, there are typically a small number of subtypes for how a disease progresses across patients. To capture this structured heterogeneity, the Subtype…

Machine Learning · Computer Science 2026-04-28 Hongtao Hao , Joseph L. Austerweil

We propose a model of brain atrophy as a function of high-dimensional genetic information and low dimensional covariates such as gender, age, APOE gene, and disease status. A nonparametric single-index Bayesian model of high dimension is…

Methodology · Statistics 2019-11-11 Arkaprava Roy , Subhashis Ghosal , Kingshuk Roy Choudhury