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Object segmentation is an important step in the workflow of computational pathology. Deep learning based models generally require large amount of labeled data for precise and reliable prediction. However, collecting labeled data is…
Diffusion models have been demonstrated as strong priors for solving general inverse problems. Most existing Diffusion model-based Inverse Problem Solvers (DIS) employ a plug-and-play approach to guide the sampling trajectory with either…
Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…
Image segmentation methods are usually trained with pixel-level annotations, which require significant human effort to collect. The most common solution to address this constraint is to implement weakly-supervised pipelines trained with…
Class-agnostic counting (CAC) aims to estimate the number of objects in images without being restricted to predefined categories. However, while current exemplar-based CAC methods offer flexibility at inference time, they still rely heavily…
Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…
Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…
Instance segmentation for unlabeled imaging modalities is a challenging but essential task as collecting expert annotation can be expensive and time-consuming. Existing works segment a new modality by either deploying a pre-trained model…
Accurate cell segmentation is critical for biological and medical imaging studies. Although recent deep learning models have advanced this task, most methods are limited to generic cell segmentation, lacking the ability to differentiate…
Although instance segmentation methods have improved considerably, the dominant paradigm is to rely on fully-annotated training images, which are tedious to obtain. To alleviate this reliance, and boost results, semi-supervised approaches…
We present a high-performance method that can achieve mask-level instance segmentation with only bounding-box annotations for training. While this setting has been studied in the literature, here we show significantly stronger performance…
Camouflaged Object Segmentation (COS) faces significant challenges due to the scarcity of annotated data, where meticulous pixel-level annotation is both labor-intensive and costly, primarily due to the intricate object-background…
Segmentation of objects in microscopy images is required for many biomedical applications. We introduce object-centric embeddings (OCEs), which embed image patches such that the spatial offsets between patches cropped from the same object…
Background: The quantitative analysis of microscope videos often requires instance segmentation and tracking of cellular and subcellular objects. The traditional method consists of two stages: (1) performing instance object segmentation of…
Human-annotated labels are often prone to noise, and the presence of such noise will degrade the performance of the resulting deep neural network (DNN) models. Much of the literature (with several recent exceptions) of learning with noisy…
Purpose: Non-invasive grading of prostate cancer (PCa) from micro-ultrasound (micro-US) could expedite triage and guide biopsies toward the most aggressive regions, yet current models struggle to infer tissue micro-structure at coarse…
Accurate and efficient registration of whole slide images (WSIs) is essential for high-resolution, nuclei-level analysis in multi-stained tissue slides. We propose a novel coarse-to-fine framework CORE for accurate nuclei-level registration…
Obtaining a large amount of labeled data in medical imaging is laborious and time-consuming, especially for histopathology. However, it is much easier and cheaper to get unlabeled data from whole-slide images (WSIs). Semi-supervised…
Weakly supervised instance segmentation (WSIS) using only image-level labels is a challenging task due to the difficulty of aligning coarse annotations with the finer task. However, with the advancement of deep neural networks (DNNs), WSIS…
Instance segmentation is an important computer vision problem which remains challenging despite impressive recent advances due to deep learning-based methods. Given sufficient training data, fully supervised methods can yield excellent…