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Robust genotype-to-phenotype (G2P) prediction is essential for accelerating breeding decisions and genetic gain. However, it remains challenging to measure complex traits under variable field conditions and across years. In this study, we…

Genomics · Quantitative Biology 2026-05-11 Yibin Wang , Murukarthick Jayakodi , Silvas Kirubakaran , Ambika Chandra , Azlan Zahid

Genotype-to-Phenotype prediction can promote advances in modern genomic research and crop improvement, guiding precision breeding and genomic selection. However, high-dimensional nonlinear features often hinder the accuracy of…

Genomics · Quantitative Biology 2025-02-27 Zeyuan Zhou , Siyuan Chen , Xinzhang Wu , Jisen Zhang , Yunxuan Dong

In this work, we propose a new deep learning model for Genomic Prediction (GP), which involves correlating genotypic data with phenotypic. The genotypes are typically fed as a sequence of characters to the 1D-Convolution Neural Network…

Machine Learning · Computer Science 2026-03-03 Kuldeep Pathak , Kapil Ahuja , Eric de Sturler

Development of either drought-resistant or drought-tolerant varieties in rice (Oryza sativa L.), especially for high yield in the context of climate change, is a crucial task across the world. The need for high yielding rice varieties is a…

Training population selection for genomic selection has captured a great deal of interest in animal and plant breeding. In this article, we derive a computationally efficient statistic to measure the reliability of estimates of genetic…

Methodology · Statistics 2014-05-22 Deniz Akdemir

Understanding how genes influence phenotype across species is a fundamental challenge in genetic engineering, which will facilitate advances in various fields such as crop breeding, conservation biology, and personalized medicine. However,…

Machine Learning · Computer Science 2025-03-11 Mengdi Liu , Zhangyang Gao , Hong Chang , Stan Z. Li , Shiguang Shan , Xilin Chen

Artificial Intelligence (AI) has emerged as a key driver of precision agriculture, facilitating enhanced crop productivity, optimized resource use, farm sustainability, and informed decision-making. Also, the expansion of genome sequencing…

Genomics · Quantitative Biology 2024-07-25 Guanjin Wang , Junyu Xuan , Penghao Wang , Chengdao Li , Jie Lu

Accurate prediction of crop yield supported by scientific and domain-relevant insights, can help improve agricultural breeding, provide monitoring across diverse climatic conditions and thereby protect against climatic challenges to crop…

Background and Aims: Prediction of phenotypic traits from new genotypes under untested environmental conditions is crucial to build simulations of breeding strategies to improve target traits. Although the plant response to environmental…

Statistics Theory · Mathematics 2010-10-27 Veronique Letort , Paul Mahe , Paul-Henry Cournède , Philippe De Reffye , Brigitte Courtois

Genomic selection (GS), as a critical crop breeding strategy, plays a key role in enhancing food production and addressing the global hunger crisis. The predominant approaches in GS currently revolve around employing statistical methods for…

Machine Learning · Computer Science 2024-06-25 Renqi Chen , Wenwei Han , Haohao Zhang , Haoyang Su , Zhefan Wang , Xiaolei Liu , Hao Jiang , Wanli Ouyang , Nanqing Dong

Retrosynthesis prediction is one of the fundamental challenges in organic chemistry and related fields. The goal is to find reactants molecules that can synthesize product molecules. To solve this task, we propose a new graph-to-graph…

Quantitative Methods · Quantitative Biology 2022-04-20 Zaiyun Lin , Shiqiu Yin , Lei Shi , Wenbiao Zhou , YingSheng Zhang

This study explores the application of machine learning-based genetic linguistics for identifying heavy metal response genes in rice (Oryza sativa). By integrating convolutional neural networks and random forest algorithms, we developed a…

Machine Learning · Computer Science 2025-03-24 Ruiqi Yang , Jianxu Wang , Wei Yuan , Xun Wang , Mei Li

Plant breeding is one of the key strategies for further enhancement of crop yields; however, effective breeding strategies require phenotypic characterisation of the available germplasm. This study sought to characterise the phenotypic…

Other Quantitative Biology · Quantitative Biology 2020-08-12 Gabriele Mongiano , Patrizia Titone , Simone Pagnoncelli , Davide Sacco , Luigi Tamborini , Roberto Pilu , Simone Bregaglio

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

A looming question that must be solved before robotic plant phenotyping capabilities can have significant impact to crop improvement programs is scalability. High Throughput Phenotyping (HTP) uses robotic technologies to analyze crops in…

Machine Learning · Computer Science 2019-01-23 Sumit Kumar , Wenhao Luo , George Kantor , Katia Sycara

Genomic Selection (GS) uses whole-genome information to predict crop phenotypes and accelerate breeding. Traditional GS methods, however, struggle with prediction accuracy for complex traits and large datasets. We propose DPCformer, a deep…

Machine Learning · Computer Science 2025-11-11 Pengcheng Deng , Kening Liu , Mengxi Zhou , Mingxi Li , Rui Yang , Chuzhe Cao , Maojun Wang , Zeyu Zhang

Precise crop yield prediction is essential for improving agricultural practices and ensuring crop resilience in varying climates. Integrating weather data across the growing season, especially for different crop varieties, is crucial for…

Machine Learning · Computer Science 2023-09-25 Zahra Khalilzadeh , Motahareh Kashanian , Saeed Khaki , Lizhi Wang

Post-genomic research deals with challenging problems in screening genomes of organisms for particular functions or potential for being the targets of genetic engineering for desirable biological features. 'Phenotyping' of wild type and…

Quantitative Methods · Quantitative Biology 2010-09-06 Hesam T. Dashti , Jernej Tonejc , Adel Ardalan , Alireza F. Siahpirani , Sabrina Guettes , Zohreh Sharif , Liya Wang , Amir H. Assadi

The number of people living in this agricultural nation of ours, which is surrounded by lush greenery, is growing on a daily basis. As a result of this, the level of arable land is decreasing, as well as residential houses and industrial…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Sadia Afrin Rimi , Md. Jalal Uddin Chowdhury , Rifat Abdullah , Iftekhar Ahmed , Mahrima Akter Mim , Mohammad Shoaib Rahman

Crop yield is a highly complex trait determined by multiple factors such as genotype, environment, and their interactions. Accurate yield prediction requires fundamental understanding of the functional relationship between yield and these…

Machine Learning · Computer Science 2019-06-12 Saeed Khaki , Lizhi Wang
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