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Large Language Models (LLMs) are susceptible to security and safety threats, such as prompt injection, prompt extraction, and harmful requests. One major cause of these vulnerabilities is the lack of an instruction hierarchy. Modern LLM…

Instruction-tuned Large Language Models (LLMs) show impressive results in numerous practical applications, but they lack essential safety features that are common in other areas of computer science, particularly an explicit separation of…

Machine Learning · Computer Science 2025-02-03 Egor Zverev , Sahar Abdelnabi , Soroush Tabesh , Mario Fritz , Christoph H. Lampert

With the advancement of technology, large language models (LLMs) have achieved remarkable performance across various natural language processing (NLP) tasks, powering LLM-integrated applications like Microsoft Copilot. However, as LLMs…

Cryptography and Security · Computer Science 2025-08-05 Yulin Chen , Haoran Li , Zihao Zheng , Yangqiu Song , Dekai Wu , Bryan Hooi

While instruction-tuned language models have demonstrated impressive zero-shot generalization, these models often struggle to generate accurate responses when faced with instructions that fall outside their training set. This paper presents…

Computation and Language · Computer Science 2024-02-20 Taehyeon Kim , Joonkee Kim , Gihun Lee , Se-Young Yun

Large Language Models (LLMs) have demonstrated exceptional proficiency in instruction-following, becoming increasingly crucial across various applications. However, this capability brings with it the risk of prompt injection attacks, where…

Computation and Language · Computer Science 2023-11-28 Zekun Li , Baolin Peng , Pengcheng He , Xifeng Yan

Large language models (LLMs) have made remarkable strides in complex reasoning tasks, but their safety and robustness in reasoning processes remain underexplored. Existing attacks on LLM reasoning are constrained by specific settings or…

Artificial Intelligence · Computer Science 2025-06-17 Jingyu Peng , Maolin Wang , Xiangyu Zhao , Kai Zhang , Wanyu Wang , Pengyue Jia , Qidong Liu , Ruocheng Guo , Qi Liu

Instruction tuning is an effective technique to align large language models (LLMs) with human intents. In this work, we investigate how an adversary can exploit instruction tuning by injecting specific instruction-following examples into…

Cryptography and Security · Computer Science 2023-10-31 Manli Shu , Jiongxiao Wang , Chen Zhu , Jonas Geiping , Chaowei Xiao , Tom Goldstein

Large language models (LLMs) have demonstrated impressive performance and have come to dominate the field of natural language processing (NLP) across various tasks. However, due to their strong instruction-following capabilities and…

Cryptography and Security · Computer Science 2026-04-10 Yulin Chen , Haoran Li , Yuan Sui , Yue Liu , Yufei He , Xiaoling Bai , Chi Fei , Yabo Li , Haozhe Ma , Yangqiu Song , Bryan Hooi

Large language models (LLMs) have significantly advanced protein representation learning. However, their capacity to interpret and design antibodies through natural language remains limited. To address this challenge, we present…

Quantitative Methods · Quantitative Biology 2026-05-21 Ling Luo , Wenbin Jiang , Hongyuan Chang , Xinkang Wang , Xushi Zhang , Yueting Xiong , Mengsha Tong , Rongshan Yu

Large language models are increasingly embedded into systems that interact with user data, retrieved web content, and external tools, creating a new attack surface: prompt injection, where malicious commands embedded in untrusted data…

Cryptography and Security · Computer Science 2026-05-05 Yuyang Gong , Zihao Wang , Jiawei Liu , XiaoFeng Wang

User representation modeling has become increasingly crucial for personalized applications, yet existing approaches struggle with generalizability across domains and sensitivity to noisy behavioral signals. We present InstructUE, an…

Machine Learning · Computer Science 2025-10-14 Ziyi Gao , Yike Xu , Jiahao Yuan , Baokun Wang , Jinyong Wen , Xiaotong Lin , Yun Liu , Xing Fu , Yu Cheng , Yongchao Liu , Weiqiang Wang , Zhongle Xie

Large Language Models (LLMs) have showcased remarkable capabilities in following human instructions. However, recent studies have raised concerns about the robustness of LLMs when prompted with instructions combining textual adversarial…

Computation and Language · Computer Science 2024-02-27 Yuansen Zhang , Xiao Wang , Zhiheng Xi , Han Xia , Tao Gui , Qi Zhang , Xuanjing Huang

Large Language Models (LLMs), while powerful, are built and trained to process a single text input. In common applications, multiple inputs can be processed by concatenating them together into a single stream of text. However, the LLM is…

Cryptography and Security · Computer Science 2024-03-25 Keegan Hines , Gary Lopez , Matthew Hall , Federico Zarfati , Yonatan Zunger , Emre Kiciman

Large Language Models (LLMs) can acquire deceptive behaviors through backdoor attacks, where the model executes prohibited actions whenever secret triggers appear in the input. Existing safety training methods largely fail to address this…

Cryptography and Security · Computer Science 2025-10-08 Guangyu Shen , Siyuan Cheng , Xiangzhe Xu , Yuan Zhou , Hanxi Guo , Zhuo Zhang , Xiangyu Zhang

We investigate security concerns of the emergent instruction tuning paradigm, that models are trained on crowdsourced datasets with task instructions to achieve superior performance. Our studies demonstrate that an attacker can inject…

Computation and Language · Computer Science 2024-04-04 Jiashu Xu , Mingyu Derek Ma , Fei Wang , Chaowei Xiao , Muhao Chen

As large language models (LLMs) are trained on massive datasets, they have raised significant privacy and ethical concerns due to their potential to inadvertently retain sensitive information. Unlearning seeks to selectively remove specific…

Computation and Language · Computer Science 2025-06-17 Philipp Spohn , Leander Girrbach , Jessica Bader , Zeynep Akata

Autoregressive models (ARMs), which predict subsequent tokens one-by-one ``from left to right,'' have achieved significant success across a wide range of sequence generation tasks. However, they struggle to accurately represent sequences…

Computation and Language · Computer Science 2025-09-04 Dhruvesh Patel , Aishwarya Sahoo , Avinash Amballa , Tahira Naseem , Tim G. J. Rudner , Andrew McCallum

Recent advances in Large Language Models (LLMs) enable exciting LLM-integrated applications, which perform text-based tasks by utilizing their advanced language understanding capabilities. However, as LLMs have improved, so have the attacks…

Cryptography and Security · Computer Science 2024-09-27 Sizhe Chen , Julien Piet , Chawin Sitawarin , David Wagner

Large language models (LLMs) are becoming increasingly prevalent in modern software systems, interfacing between the user and the Internet to assist with tasks that require advanced language understanding. To accomplish these tasks, the LLM…

Cryptography and Security · Computer Science 2025-07-04 Sizhe Chen , Arman Zharmagambetov , Saeed Mahloujifar , Kamalika Chaudhuri , David Wagner , Chuan Guo

System Instructions in Large Language Models (LLMs) are commonly used to enforce safety policies, define agent behavior, and protect sensitive operational context in agentic AI applications. These instructions may contain sensitive…

Cryptography and Security · Computer Science 2026-04-02 Anubhab Sahu , Diptisha Samanta , Reza Soosahabi
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