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Deep-Brain Stimulation (DBS) is a therapy used in conjunction with medication to help alleviate the motor symptoms of Parkinson's Disease (PD). However, the monitoring and adjustment of DBS settings is tedious and expensive, requiring long…

Neurons and Cognition · Quantitative Biology 2019-12-03 Huy Phi , Sanjeev Janarthanan , Larry Zhang , Reza Hosseini Ghomi

Depression, a prevalent mental health disorder impacting millions globally, demands reliable assessment systems. Unlike previous studies that focus solely on either detecting depression or predicting its severity, our work identifies…

Detecting sleepiness from spoken language is an ambitious task, which is addressed by the Interspeech 2019 Computational Paralinguistics Challenge (ComParE). We propose an end-to-end deep learning approach to detect and classify patterns…

Sound · Computer Science 2020-04-01 Daniel Elsner , Stefan Langer , Fabian Ritz , Robert Müller , Steffen Illium

Overlapping Speech Detection (OSD) aims to identify regions where multiple speakers overlap in a conversation, a critical challenge in multi-party speech processing. This work proposes a speaker-aware progressive OSD model that leverages a…

Sound · Computer Science 2025-05-30 Zhaokai Sun , Li Zhang , Qing Wang , Pan Zhou , Lei Xie

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Maryam Allahbakhshi , Aylar Sadri , Seyed Omid Shahdi

Sound processing in the human auditory system is complex and highly non-linear, whereas hearing aids (HAs) still rely on simplified descriptions of auditory processing or hearing loss to restore hearing. Even though standard HA…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-21 Fotios Drakopoulos , Sarah Verhulst

Facial phenotyping has recently been successfully exploited for medical diagnosis as a novel way to diagnose a range of diseases, where facial biometrics has been revealed to have rich links to underlying genetic or medical causes. In this…

Artificial Intelligence · Computer Science 2021-05-18 Richard Jiang , Paul Chazot , Danny Crookes , Ahmed Bouridane , M Emre Celebi

Bipolar disorder (BD) and borderline personality disorder (BPD) are both chronic psychiatric disorders. However, their overlapping symptoms and common comorbidity make it challenging for the clinicians to distinguish the two conditions on…

Machine Learning · Computer Science 2021-06-01 Bo Wang , Yue Wu , Niall Taylor , Terry Lyons , Maria Liakata , Alejo J Nevado-Holgado , Kate E A Saunders

Voice-based digital biomarkers can enable scalable, non-invasive screening and monitoring of Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS). However, models trained on one cohort or device often fail on new acquisition…

Speaker-independent speech separation has achieved remarkable performance in recent years with the development of deep neural network (DNN). Various network architectures, from traditional convolutional neural network (CNN) and recurrent…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-17 Xue Yang , Changchun Bao

Speech contains information that is clinically relevant to some diseases, which has the potential to be used for health assessment. Recent work shows an interest in applying deep learning algorithms, especially pretrained large speech…

Sound · Computer Science 2024-07-02 Hok-Shing Lau , Mark Huntly , Nathon Morgan , Adesua Iyenoma , Biao Zeng , Tim Bashford

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

Sound · Computer Science 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Speech-based depression detection has shown promise as an objective diagnostic tool, yet the cross-linguistic robustness of acoustic markers and their neurobiological underpinnings remain underexplored. This study extends Cross-Data…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Fuxiang Tao , Dongwei Li , Shuning Tang , Xuri Ge , Wei Ma , Anna Esposito , Alessandro Vinciarelli

Deep transformer models have been used to detect linguistic anomalies in patient transcripts for early Alzheimer's disease (AD) screening. While pre-trained neural language models (LMs) fine-tuned on AD transcripts perform well, little…

Computation and Language · Computer Science 2025-06-09 Zhecheng Sheng , Xiruo Ding , Brian Hur , Changye Li , Trevor Cohen , Serguei Pakhomov

Parkinson's Disease (PD) is associated with gait movement disorders, such as bradykinesia, stiffness, tremors and postural instability, caused by progressive dopamine deficiency. Today, some approaches have implemented learning…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Edgar Rangel , Fabio Martinez

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Aphasia is a language disorder that can lead to speech errors known as paraphasias, which involve the misuse, substitution, or invention of words. Automatic paraphasia detection can help those with Aphasia by facilitating clinical…

Computation and Language · Computer Science 2024-07-17 Matthew Perez , Aneesha Sampath , Minxue Niu , Emily Mower Provost

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang
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