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Retinal vascular diseases affect the well-being of human body and sometimes provide vital signs of otherwise undetected bodily damage. Recently, deep learning techniques have been successfully applied for detection of diabetic retinopathy…

Machine Learning · Computer Science 2022-01-05 Guan Wang , Yusuke Kikuchi , Jinglin Yi , Qiong Zou , Rui Zhou , Xin Guo

Visual explanation methods have an important role in the prognosis of the patients where the annotated data is limited or unavailable. There have been several attempts to use gradient-based attribution methods to localize pathology from…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Ugur Demir , Ismail Irmakci , Elif Keles , Ahmet Topcu , Ziyue Xu , Concetto Spampinato , Sachin Jambawalikar , Evrim Turkbey , Baris Turkbey , Ulas Bagci

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

Fine-grained glomerular subtyping is central to kidney biopsy interpretation, but clinically valuable labels are scarce and difficult to obtain. Existing computational pathology approaches instead tend to evaluate coarse diseased…

Diabetic Retinopathy (DR) is a complication of long-standing, unchecked diabetes and one of the leading causes of blindness in the world. This paper focuses on improved and robust methods to extract some of the features of DR, viz. Blood…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Soham Basu , Sayantan Mukherjee , Ankit Bhattacharya , Anindya Sen

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Sleep stage classification based on electroencephalography (EEG) is fundamental for assessing sleep quality and diagnosing sleep-related disorders. However, most traditional machine learning methods rely heavily on prior knowledge and…

Artificial Intelligence · Computer Science 2025-11-25 Xihe Qiu , Gengchen Ma , Haoyu Wang , Chen Zhan , Xiaoyu Tan , Shuo Li

Recently, Geometric Deep Learning (GDL) has been introduced as a novel and versatile framework for computer-aided disease classification. GDL uses patient meta-information such as age and gender to model patient cohort relations in a graph…

Machine Learning · Computer Science 2020-05-05 Hendrik Burwinkel , Anees Kazi , Gerome Vivar , Shadi Albarqouni , Guillaume Zahnd , Nassir Navab , Seyed-Ahmad Ahmadi

In histopathology, tissue sections are typically stained using common H&E staining or special stains (MAS, PAS, PASM, etc.) to clearly visualize specific tissue structures. The rapid advancement of deep learning offers an effective solution…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Zizhi Chen , Xinyu Zhang , Minghao Han , Yizhou Liu , Ziyun Qian , Weifeng Zhang , Xukun Zhang , Jingwei Wei , Lihua Zhang

In precision medicine, quantitative multi-omic features, topological context, and textual biological knowledge play vital roles in identifying disease-critical signaling pathways and targets. Existing pipelines capture only part of…

Artificial Intelligence · Computer Science 2025-12-17 Heming Zhang , Di Huang , Wenyu Li , Michael Province , Yixin Chen , Philip Payne , Fuhai Li

The growing success of Vision-Language-Action (VLA) models stems from the promise that pretrained Vision-Language Models (VLMs) can endow agents with transferable world knowledge and vision-language (VL) grounding, laying a foundation for…

Machine Learning · Computer Science 2025-10-30 Nikita Kachaev , Mikhail Kolosov , Daniil Zelezetsky , Alexey K. Kovalev , Aleksandr I. Panov

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

Large-scale contrastive pre-training produces powerful Vision-and-Language Models (VLMs) capable of generating representations (embeddings) effective for a wide variety of visual and multimodal tasks. However, these pretrained embeddings…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Nikolaos-Antonios Ypsilantis , Kaifeng Chen , André Araujo , Ondřej Chum

The task of grading atopic dermatitis (or AD, a form of eczema) from patient images is difficult even for trained dermatologists. Research on automating this task has progressed in recent years with the development of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Marc Lalonde , Hamed Ghodrati

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Reasoning is a critical frontier for advancing medical image analysis, where transparency and trustworthiness play a central role in both clinician trust and regulatory approval. Although Medical Visual Language Models (VLMs) show promise…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Jiazhen Pan , Che Liu , Junde Wu , Fenglin Liu , Jiayuan Zhu , Hongwei Bran Li , Chen Chen , Cheng Ouyang , Daniel Rueckert

The way we analyse clinical texts has undergone major changes over the last years. The introduction of language models such as BERT led to adaptations for the (bio)medical domain like PubMedBERT and ClinicalBERT. These models rely on large…

Computation and Language · Computer Science 2023-09-15 Tom van Sonsbeek , Xiantong Zhen , Marcel Worring

Recent advances in visual-language machine learning models have demonstrated exceptional ability to use natural language and understand visual scenes by training on large, unstructured datasets. However, this training paradigm cannot…

Computation and Language · Computer Science 2025-08-01 Anthony C Davis , Burhan Sadiq , Tianmin Shu , Chien-Ming Huang

Disentangled representation learning (DRL) aims to identify and decompose underlying factors behind observations, thus facilitating data perception and generation. However, current DRL approaches often rely on the unrealistic assumption…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Baao Xie , Qiuyu Chen , Yunnan Wang , Zequn Zhang , Xin Jin , Wenjun Zeng

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian