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Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Hanwen Liang , Konstantinos N. Plataniotis , Xingyu Li

Virtual stain transfer is a promising area of research in Computational Pathology, which has a great potential to alleviate important limitations when applying deeplearningbased solutions such as lack of annotations and sensitivity to a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

Contrastive learning has emerged as a powerful tool for graph representation learning. However, most contrastive learning methods learn features of graphs with fixed coarse-grained scale, which might underestimate either local or global…

Machine Learning · Computer Science 2022-10-24 Jun Wang , Weixun Li , Changyu Hou , Xin Tang , Yixuan Qiao , Rui Fang , Pengyong Li , Peng Gao , Guotong Xie

Heterogeneous graphs (HGs) are composed of multiple types of nodes and edges, making it more effective in capturing the complex relational structures inherent in the real world. However, in real-world scenarios, labeled data is often…

Machine Learning · Computer Science 2025-08-20 Ruobing Jiang , Yacong Li , Haobing Liu , Yanwei Yu

The effectiveness of contrastive learning methods has been widely recognized in the field of graph learning, especially in contexts where graph data often lack labels or are difficult to label. However, the application of these methods to…

Machine Learning · Computer Science 2026-01-16 Qiang Yu , Xinran Cheng , Shiqiang Xu , Chuanyi Liu

Link prediction tasks focus on predicting possible future connections. Most existing researches measure the likelihood of links by different similarity scores on node pairs and predict links between nodes. However, the similarity-based…

Machine Learning · Computer Science 2023-03-09 Zehua Zhang , Shilin Sun , Guixiang Ma , Caiming Zhong

Hypergraphs can model higher-order relationships among data objects that are found in applications such as social networks and bioinformatics. However, recent studies on hypergraph learning that extend graph convolutional networks to…

Machine Learning · Computer Science 2024-05-29 Yumeng Song , Yu Gu , Tianyi Li , Jianzhong Qi , Zhenghao Liu , Christian S. Jensen , Ge Yu

Variability in staining protocols, such as different slide preparation techniques, chemicals, and scanner configurations, can result in a diverse set of whole slide images (WSIs). This distribution shift can negatively impact the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Kudaibergen Abutalip , Numan Saeed , Mustaqeem Khan , Abdulmotaleb El Saddik

Image style transfer has attracted widespread attention in the past few years. Despite its remarkable results, it requires additional style images available as references, making it less flexible and inconvenient. Using text is the most…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Zhi-Song Liu , Li-Wen Wang , Jun Xiao , Vicky Kalogeiton

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

Medical Physics · Physics 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Inspired by the success of contrastive learning (CL) in computer vision and natural language processing, graph contrastive learning (GCL) has been developed to learn discriminative node representations on graph datasets. However, the…

Machine Learning · Computer Science 2023-01-03 Zehong Wang , Qi Li , Donghua Yu , Xiaolong Han , Xiao-Zhi Gao , Shigen Shen

Graph contrastive learning (CL) methods learn node representations in a self-supervised manner by maximizing the similarity between the augmented node representations obtained via a GNN-based encoder. However, CL methods perform poorly on…

Machine Learning · Computer Science 2024-06-12 Wenhan Yang , Baharan Mirzasoleiman

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Heterogeneous graph neural networks (HGNNs) as an emerging technique have shown superior capacity of dealing with heterogeneous information network (HIN). However, most HGNNs follow a semi-supervised learning manner, which notably limits…

Machine Learning · Computer Science 2024-03-06 Nian Liu , Xiao Wang , Hui Han , Chuan Shi

Graph classification has gained significant attention due to its applications in chemistry, social networks, and bioinformatics. While Graph Neural Networks (GNNs) effectively capture local structural patterns, they often overlook global…

Machine Learning · Computer Science 2025-12-03 Ahmet Sami Korkmaz , Selim Coskunuzer , Md Joshem Uddin

Drug-target interaction (DTI) prediction is crucial for drug development and repositioning. Methods using heterogeneous graph neural networks (HGNNs) for DTI prediction have become a promising approach, with attention-based models often…

Biomolecules · Quantitative Biology 2024-11-05 Junwei Hu , Michael Bewong , Selasi Kwashie , Wen Zhang , Vincent M. Nofong , Guangsheng Wu , Zaiwen Feng

Graph Contrastive Learning (GCL) seeks to learn nodal or graph representations that contain maximal consistent information from graph-structured data. While node-level contrasting modes are dominating, some efforts commence to explore…

Machine Learning · Computer Science 2024-09-13 Zhenhao Zhao , Minhong Zhu , Chen Wang , Sijia Wang , Jiqiang Zhang , Li Chen , Weiran Cai

Heterogeneous graph neural networks (HGNNs) have significantly propelled the information retrieval (IR) field. Still, the effectiveness of HGNNs heavily relies on high-quality labels, which are often expensive to acquire. This challenge has…

Machine Learning · Computer Science 2024-09-12 Siqing Li , Jin-Duk Park , Wei Huang , Xin Cao , Won-Yong Shin , Zhiqiang Xu

In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Objective: This work addresses two key problems of skin lesion classification. The first problem is the effective use of high-resolution images with pretrained standard architectures for image classification. The second problem is the high…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Nils Gessert , Thilo Sentker , Frederic Madesta , Rüdiger Schmitz , Helge Kniep , Ivo Baltruschat , René Werner , Alexander Schlaefer