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Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

Machine Learning · Computer Science 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

The cosmic microwave background power spectra are a primary window into the early universe. However, achieving interpretable, likelihood-compatible compression and fast inference under weak model assumptions remains challenging. We propose…

Cosmology and Nongalactic Astrophysics · Physics 2025-11-03 Tian-Yang Sun , Tian-Nuo Li , He Wang , Jing-Fei Zhang , Xin Zhang

Variational Autoencoders (VAEs) typically rely on a probabilistic decoder with a predefined likelihood, most commonly an isotropic Gaussian, to model the data conditional on latent variables. While convenient for optimization, this choice…

Machine Learning · Statistics 2025-04-29 Chen Xu , Qiang Wang , Lijun Sun

Variational auto-encoder (VAE) is a powerful unsupervised learning framework for image generation. One drawback of VAE is that it generates blurry images due to its Gaussianity assumption and thus L2 loss. To allow the generation of high…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Lei Cai , Hongyang Gao , Shuiwang Ji

Medical images are acquired at high resolutions with large fields of view in order to capture fine-grained features necessary for clinical decision-making. Consequently, training deep learning models on medical images can incur large…

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Variational Auto-encoders (VAEs) have been very successful as methods for forming compressed latent representations of complex, often high-dimensional, data. In this paper, we derive an alternative variational lower bound from the one…

Machine Learning · Computer Science 2019-03-20 Shuyu Lin , Ronald Clark , Robert Birke , Niki Trigoni , Stephen Roberts

Variational autoencoders are prominent generative models for modeling discrete data. However, with flexible decoders, they tend to ignore the latent codes. In this paper, we study a VAE model with a deterministic decoder (DD-VAE) for…

Machine Learning · Computer Science 2020-03-05 Daniil Polykovskiy , Dmitry Vetrov

Advances in latent diffusion models (LDMs) have revolutionized high-resolution image generation, but the design space of the autoencoder that is central to these systems remains underexplored. In this paper, we introduce LiteVAE, a new…

Machine Learning · Computer Science 2025-01-22 Seyedmorteza Sadat , Jakob Buhmann , Derek Bradley , Otmar Hilliges , Romann M. Weber

Virtual beam diagnostics relies on computationally intensive beam dynamics simulations where high-dimensional charged particle beams evolve through the accelerator. We propose Latent Evolution Model (LEM), a hybrid machine learning…

Accelerator Physics · Physics 2026-02-27 Mahindra Rautela , Alexander Scheinker

We propose a cross-domain latent modulation mechanism within a variational autoencoders (VAE) framework to enable improved transfer learning. Our key idea is to procure deep representations from one data domain and use it as perturbation to…

Machine Learning · Computer Science 2020-12-23 Jinyong Hou , Jeremiah D. Deng , Stephen Cranefield , Xuejie Ding

Multimodal learning combining pathology images and genomic sequences enhances cancer survival analysis but faces clinical implementation barriers due to limited access to genomic sequencing in under-resourced regions. To enable survival…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zizhi Chen , Minghao Han , Xukun Zhang , Shuwei Ma , Tao Liu , Xing Wei , Lihua Zhang

Despite the increasing use of deep learning in medical image segmentation, acquiring sufficient training data remains a challenge in the medical field. In response, data augmentation techniques have been proposed; however, the generation of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Learning interpretable representations of data remains a central challenge in deep learning. When training a deep generative model, the observed data are often associated with certain categorical labels, and, in parallel with learning to…

Machine Learning · Computer Science 2019-10-01 Yifan Xue , Michael Ding , Xinghua Lu

In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression ratio of 1:512, which is better than the previously reported state of the art…

We investigate a variant of variational autoencoders where there is a superstructure of discrete latent variables on top of the latent features. In general, our superstructure is a tree structure of multiple super latent variables and it is…

Machine Learning · Computer Science 2019-02-25 Xiaopeng Li , Zhourong Chen , Leonard K. M. Poon , Nevin L. Zhang

Extracorporeal membrane oxygenation (ECMO) is an essential life-supporting modality for COVID-19 patients who are refractory to conventional therapies. However, the proper treatment decision has been the subject of significant debate and it…

Machine Learning · Computer Science 2023-07-10 Bing Xue , Ahmed Sameh Said , Ziqi Xu , Hanyang Liu , Neel Shah , Hanqing Yang , Philip Payne , Chenyang Lu

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

Variational Autoencoders and Generative Adversarial Networks remained the state-of-the-art (SOTA) generative models until 2022. Now they are superseded by diffusion-based models. Efforts to improve traditional models have stagnated as a…

Machine Learning · Computer Science 2026-03-10 Tuhin Subhra De

Multimodal variational autoencoders have demonstrated their ability to learn the relationships between different modalities by mapping them into a latent representation. Their design and capacity to perform any-to-any conditional and…

Machine Learning · Computer Science 2025-02-04 Daniel Wesego , Pedram Rooshenas