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The quantum approximate optimization algorithm (QAOA) is a hybrid variational quantum-classical algorithm that solves combinatorial optimization problems. While there is evidence suggesting that the fixed form of the standard QAOA ansatz is…

The Quantum Approximate Optimization Algorithm (QAOA) and its advanced variant, the Quantum Alternating Operator Ansatz (QAOA), are major research topics in the current era of Noisy Intermediate-Scale Quantum (NISQ) computing. However, the…

Quantum Physics · Physics 2026-03-23 Shuai Zeng

We show through numerical simulation that the Quantum Approximate Optimization Algorithm (QAOA) for higher-order, random-coefficient, heavy-hex compatible spin glass Ising models has strong parameter concentration across problem sizes from…

Quantum Physics · Physics 2024-11-13 Elijah Pelofske , Andreas Bärtschi , Lukasz Cincio , John Golden , Stephan Eidenbenz

Quantum optimization solvers typically rely on one-variable-to-one-qubit mapping. However, the low qubit count on current quantum computers is a major obstacle in competing against classical methods. Here, we develop a qubit-efficient…

Quantum Physics · Physics 2026-03-24 Bhuvanesh Sundar , Maxime Dupont

The quasi-independent curvilinear coordinate approximation (QUICCA) method [K. N\'emeth and M. Challacombe, J. Chem. Phys. {\bf 121}, 2877, (2004)] is extended to the optimization of crystal structures. We demonstrate that QUICCA is valid…

Chemical Physics · Physics 2009-11-11 Karoly Nemeth , Matt Challacombe

Discrete combinatorial optimization consists in finding the optimal configuration that minimizes a given discrete objective function. An interpretation of such a function as the energy of a classical system allows us to reduce the…

Quantum Physics · Physics 2015-06-22 Sergio Boixo , Gerardo Ortiz , Rolando Somma

We present a detailed study of portfolio optimization using different versions of the quantum approximate optimization algorithm (QAOA). For a given list of assets, the portfolio optimization problem is formulated as quadratic binary…

Quantum computing is a computational paradigm with the potential to outperform classical methods for a variety of problems. Proposed recently, the Quantum Approximate Optimization Algorithm (QAOA) is considered as one of the leading…

Machine Learning · Computer Science 2022-06-16 Sami Khairy , Ruslan Shaydulin , Lukasz Cincio , Yuri Alexeev , Prasanna Balaprakash

To discover novel materials with high performance, there have been many attempts to adopt Bayesian optimization (BO) to materials science, owing to its efficiency in navigating complex and high-dimensional design spaces. However, the…

Materials Science · Physics 2025-05-12 Sanghyeon Park , Yoonsu Shim , Junpyo Hur , Dongmin Jeon , Jong Min Yuk , Chan-Woo Lee

Approximate combinatorial optimization is a promising use case for quantum computers. The quantum optimization algorithms often employ a fixed ansatz that evolves an unbiased initial state towards states with better values of the optimand,…

Quantum Physics · Physics 2026-04-30 Phillip C. Lotshaw , Titus Morris , Stuart Hadfield , Ryan Bennink

The Quantum Approximate Optimization Algorithm (QAOA) is a hybrid quantum-classical algorithm to solve binary-variable optimization problems. Due to the short circuit depth and its expected robustness to systematic errors, it is one of the…

Quantum Physics · Physics 2022-08-23 Jason Larkin , Matías Jonsson , Daniel Justice , Gian Giacomo Guerreschi

A novel class of hybrid quantum-classical algorithms based on the variational approach have recently emerged from separate proposals addressing, for example, quantum chemistry and combinatorial problems. These algorithms provide an…

Quantum Physics · Physics 2017-01-09 Gian Giacomo Guerreschi , Mikhail Smelyanskiy

We introduce a computational method for global optimization of structure and ordering in atomic systems. The method relies on interpolation between chemical elements, which is incorporated in a machine learning structural fingerprint. The…

Materials Science · Physics 2021-10-18 Sami Kaappa , Casper Larsen , Karsten Wedel Jacobsen

Quantum Approximate Optimization Algorithm (QAOA) is one of the most promising quantum algorithms for the Noisy Intermediate-Scale Quantum (NISQ) era. Quantifying the performance of QAOA in the near-term regime is of utmost importance. We…

Quantum Physics · Physics 2022-06-16 Ruslan Shaydulin , Yuri Alexeev

The Quantum Approximate Optimization Algorithm (QAOA) is a promising approach for programming a near-term gate-based hybrid quantum computer to find good approximate solutions of hard combinatorial problems. However, little is currently…

Quantum Physics · Physics 2018-11-21 Gavin E. Crooks

Evolutionary crystal structure prediction proved to be a powerful approach for studying a wide range of materials. Here, we present a specifically designed algorithm for the prediction of the structure of complex crystals consisting of…

Materials Science · Physics 2012-05-21 Qiang Zhu , Artem R. Oganov , Colin W. Glass , Harold T. Stokes

Modelling and predicting protein configurations is crucial for advancing drug discovery, enabling the design of treatments for life-threatening diseases. A critical aspect of this challenge is rotamer optimisation - the determination of…

Quantum Physics · Physics 2025-07-28 Anastasia Agathangelou , Dilhan Manawadu , Ivano Tavernelli

The Quantum Approximate Optimization Algorithm (QAOA) is a general-purpose algorithm for combinatorial optimization problems whose performance can only improve with the number of layers $p$. While QAOA holds promise as an algorithm that can…

Quantum Physics · Physics 2022-07-08 Edward Farhi , Jeffrey Goldstone , Sam Gutmann , Leo Zhou

There is a large ongoing research effort towards obtaining a quantum advantage in the solution of combinatorial optimization problems on near-term quantum devices. A particularly promising platform for testing and developing quantum…

In order to qualify quantum algorithms for industrial NP-Hard problems, comparing them to available polynomial approximate classical algorithms and not only to exact ones -- exponential by nature -- , is necessary. This is a great challenge…