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In this work we generalize the plain MS trackers and attempt to overcome standard mean shift trackers' two limitations. It is well known that modeling and maintaining a representation of a target object is an important component of a…

Computer Vision and Pattern Recognition · Computer Science 2009-06-07 Chunhua Shen , Junae Kim , Hanzi Wang

Nowadays, more and more process data are automatically recorded by information systems, and made available in the form of event logs. Process mining techniques enable process-centric analysis of data, including automatically discovering…

Artificial Intelligence · Computer Science 2022-04-11 Marco Pegoraro , Wil M. P. van der Aalst

State-of-the-art object detection and segmentation methods for microscopy images rely on supervised machine learning, which requires laborious manual annotation of training data. Here we present a self-supervised method based on time arrow…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Benjamin Gallusser , Max Stieber , Martin Weigert

Uncertainty quantification of complex technical systems is often based on a computer model of the system. As all models such a computer model is always wrong in the sense that it does not describe the reality perfectly. The purpose of this…

Systems and Control · Electrical Eng. & Systems 2020-12-18 Sebastian Kersting , Michael Kohler

Table structure recognition is necessary for a comprehensive understanding of documents. Tables in unstructured business documents are tough to parse due to the high diversity of layouts, varying alignments of contents, and the presence of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Sachin Raja , Ajoy Mondal , C V Jawahar

The ability to identify and resolve uncertainty is crucial for the robustness of a dialogue system. Indeed, this has been confirmed empirically on systems that utilise Bayesian approaches to dialogue belief tracking. However, such systems…

Computation and Language · Computer Science 2021-09-10 Carel van Niekerk , Andrey Malinin , Christian Geishauser , Michael Heck , Hsien-chin Lin , Nurul Lubis , Shutong Feng , Milica Gašić

The annotation of disease severity for medical image datasets often relies on collaborative decisions from multiple human graders. The intra-observer variability derived from individual differences always persists in this process, yet the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Chi Liu , Zongyuan Ge , Mingguang He , Xiaotong Han

Uncertainty estimation is critical for numerous applications of deep neural networks and draws growing attention from researchers. Here, we demonstrate an uncertainty quantification approach for deep neural networks used in inverse problems…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Luzhe Huang , Jianing Li , Xiaofu Ding , Yijie Zhang , Hanlong Chen , Aydogan Ozcan

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

The proliferation of Deep Neural Networks has resulted in machine learning systems becoming increasingly more present in various real-world applications. Consequently, there is a growing demand for highly reliable models in many domains,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Pedro Conde , Rui L. Lopes , Cristiano Premebida

Image-to-image regression is an important learning task, used frequently in biological imaging. Current algorithms, however, do not generally offer statistical guarantees that protect against a model's mistakes and hallucinations. To…

Classifiers are often tested on relatively small data sets, which should lead to uncertain performance metrics. Nevertheless, these metrics are usually taken at face value. We present an approach to quantify the uncertainty of…

Machine Learning · Statistics 2021-03-05 Niklas Tötsch , Daniel Hoffmann

Increasingly sophisticated experiments, coupled with large-scale computational models, have the potential to systematically test biological hypotheses to drive our understanding of multicellular systems. In this short review, we explore key…

Quantitative Methods · Quantitative Biology 2019-10-28 Paul Macklin

Integrating heterogeneous datasets across different measurement platforms is a fundamental challenge in many scientific applications. A common example arises in deconvolution problems, such as cell type deconvolution, where one aims to…

Methodology · Statistics 2025-09-30 Dongyue Xie , Lin Gui , Jingshu Wang

Epigenetic Tracking is a mathematical model of biological cells, originally conceived to study embryonic development. Computer simulations proved the capacity of the model to generate complex 3-dimensional cellular structures, and the…

Cell Behavior · Quantitative Biology 2015-07-07 Alessandro Fontana

We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Chong Zhang , Shaofei Wang , Miguel A. Gonzalez-Ballester , Julian Yarkony

To ensure safe clinical integration, deep learning models must provide more than just high accuracy; they require dependable uncertainty quantification. While current Medical Vision Transformers perform well, they frequently struggle with…

Image and Video Processing · Electrical Eng. & Systems 2026-04-13 Mohammed Maaz Sibhai , Abedalrhman Alkhateeb , Saad B. Ahmed

Deep neural networks are powerful tools to detect hidden patterns in data and leverage them to make predictions, but they are not designed to understand uncertainty and estimate reliable probabilities. In particular, they tend to be…

Machine Learning · Statistics 2022-11-10 Bat-Sheva Einbinder , Yaniv Romano , Matteo Sesia , Yanfei Zhou

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma