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The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

An important and well-studied problem in phylogenetics is to compute a \emph{consensus tree} so as to summarize the common features within a collection of rooted phylogenetic trees, all whose leaf-sets are bijectively labeled by the same…

Populations and Evolution · Quantitative Biology 2021-07-22 Katharina T. Huber , Vincent Moulton , Andreas Spillner

We derive tractable criteria for the consistency of Bayesian tree reconstruction procedures, which constitute a central class of algorithms for inferring common ancestry among DNA sequence samples in phylogenetics. Our results encompass…

Statistics Theory · Mathematics 2025-08-05 Alisa Kirichenko , Luke J. Kelly , Jere Koskela

The tree-metric theorem provides a necessary and sufficient condition for a dissimilarity matrix to be a tree metric, and has served as the foundation for numerous distance-based reconstruction methods in phylogenetics. Our main result is…

Combinatorics · Mathematics 2007-05-23 Lior Pachter , David E Speyer

Random Forests (RF) is a popular machine learning method for classification and regression problems. It involves a bagging application to decision tree models. One of the primary advantages of the Random Forests model is the reduction in…

Machine Learning · Statistics 2022-07-06 Sai K Popuri

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski

A spanning 2-forest separating vertices $u$ and $v$ of an undirected connected graph is a spanning forest with 2 components such that $u$ and $v$ are in distinct components. Aside from their combinatorial significance, spanning 2-forests…

Combinatorics · Mathematics 2019-05-17 Wayne Barrett , Emily J. Evans , Amanda E. Francis , Mark Kempton , John Sinkovic

Recently, so-called treebased phylogenetic networks have gained considerable interest in the literature, where a treebased network is a network that can be constructed from a phylogenetic tree, called the base tree, by adding additional…

Populations and Evolution · Quantitative Biology 2019-11-28 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

Data Structures and Algorithms · Computer Science 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca

Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

Data Structures and Algorithms · Computer Science 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

Despite the latest prevailing success of deep neural networks (DNNs), several concerns have been raised against their usage, including the lack of intepretability the gap between DNNs and other well-established machine learning models, and…

Machine Learning · Computer Science 2021-01-01 Jianghao Shen , Sicheng Wang , Zhangyang Wang

A fundamental problem in network science is the normalization of the topological or physical distance between vertices, that requires understanding the range of variation of the unnormalized distances. Here we investigate the limits of the…

Discrete Mathematics · Computer Science 2021-02-18 Ramon Ferrer-i-Cancho , Carlos Gómez-Rodríguez , Juan Luis Esteban

We prove a lower bound on the number of spanning two-forests in a graph, in terms of the number of vertices, edges, and spanning trees. This implies an upper bound on the average cut size of a random two-forest. The main tool is an identity…

Combinatorics · Mathematics 2023-08-09 Harry Richman , Farbod Shokrieh , Chenxi Wu

Many natural language processing (NLP) applications require the computation of similarities between pairs of syntactic or semantic trees. Many researchers have used tree edit distance for this task, but this technique suffers from the…

Computation and Language · Computer Science 2014-02-05 Maytham Alabbas , Allan Ramsay

Merge trees are a type of graph-based topological summary that tracks the evolution of connected components in the sublevel sets of scalar functions. They enjoy widespread applications in data analysis and scientific visualization. In this…

Computational Geometry · Computer Science 2022-02-03 Ellen Gasparovic , Elizabeth Munch , Steve Oudot , Katharine Turner , Bei Wang , Yusu Wang

Assume we are given a set of items from a general metric space, but we neither have access to the representation of the data nor to the distances between data points. Instead, suppose that we can actively choose a triplet of items (A,B,C)…

Machine Learning · Statistics 2018-06-19 Siavash Haghiri , Damien Garreau , Ulrike von Luxburg

The interleaving distance is a key tool for comparing merge trees, which provide topological summaries of scalar functions. In this work, we define an average merge tree for a pair of merge trees using the interleaving distance. Since such…

Computational Geometry · Computer Science 2026-03-03 Elena Farahbakhsh Touli , Ingrid Hotz , Talha Bin Masood

Rotation distances measure the differences in structure between rooted ordered binary trees. The one-dimensional skeleta of associahedra are rotation graphs, where two vertices representing trees are connected by an edge if they differ by a…

Data Structures and Algorithms · Computer Science 2020-06-29 Sean Cleary , Haris Nadeem

Domain generalization is a popular machine learning technique that enables models to perform well on the unseen target domain, by learning from multiple source domains. Domain generalization is useful in cases where data is limited,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Yuyang Sun , Panagiotis Kosmas

The Neighbor-Joining algorithm is a recursive procedure for reconstructing trees that is based on a transformation of pairwise distances between leaves. We present a generalization of the neighbor-joining transformation, which uses…

Quantitative Methods · Quantitative Biology 2007-05-23 Dan Levy , Ruriko Yoshida , Lior Pachter