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Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

In computational anatomy, the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework has become a central tool for modeling smooth, invertible transformations between shapes such as curves or landmarks. In this paper, we extend…

Differential Geometry · Mathematics 2025-11-19 Rayane Mouhli , Thomas Pierron

Unsupervised deep-learning (DL) models were recently proposed for deformable image registration tasks. In such models, a neural-network is trained to predict the best deformation field by minimizing some dissimilarity function between the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-11 Samah Khawaled , Moti Freiman

We introduce DFReg, a physics-inspired regularization method for deep neural networks that operates on the global distribution of weights. Drawing from Density Functional Theory (DFT), DFReg applies a functional penalty to encourage smooth,…

Machine Learning · Computer Science 2025-07-02 Giovanni Ruggieri

The substantial modality-induced variations in radiometric, texture, and structural characteristics pose significant challenges for the accurate registration of multimodal images. While supervised deep learning methods have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Xiaochen Wei , Weiwei Guo , Wenxian Yu

We introduce RetinaRegNet, a zero-shot image registration model designed to register retinal images with minimal overlap, large deformations, and varying image quality. RetinaRegNet addresses these challenges and achieves robust and…

Tracking microsctructural changes in the developing brain relies on accurate inter-subject image registration. However, most methods rely on either structural or diffusion data to learn the spatial correspondences between two or more…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Irina Grigorescu , Alena Uus , Daan Christiaens , Lucilio Cordero-Grande , Jana Hutter , A. David Edwards , Joseph V. Hajnal , Marc Modat , Maria Deprez

Current approaches for deformable medical image registration often struggle to fulfill all of the following criteria: versatile applicability, small computation or training times, and the being able to estimate large deformations.…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Hanna Siebert , Lasse Hansen , Mattias P. Heinrich

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Deformable image registration is able to achieve fast and accurate alignment between a pair of images and thus plays an important role in many medical image studies. The current deep learning (DL)-based image registration approaches…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Xinke Ma , Yibo Yang , Yong Xia , Dacheng Tao

Federated Learning (FL) in Deep Learning (DL)-automated medical image segmentation helps preserving privacy by enabling collaborative model training without sharing patient data. However, FL faces challenges with data heterogeneity among…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Philip Schutte , Valentina Corbetta , Regina Beets-Tan , Wilson Silva

Accurate tracking of an anatomical landmark over time has been of high interests for disease assessment such as minimally invasive surgery and tumor radiation therapy. Ultrasound imaging is a promising modality benefiting from low-cost and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Zhihua Liu , Bin Yang , Yan Shen , Xuejun Ni , Huiyu Zhou

The goal of image registration is to establish spatial correspondence between two or more images, traditionally through dense displacement fields (DDFs) or parametric transformations (e.g., rigid, affine, and splines). Rethinking the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Shiqi Huang , Tingfa Xu , Ziyi Shen , Shaheer Ullah Saeed , Wen Yan , Dean Barratt , Yipeng Hu

Distance metric learning (DML) has been successfully applied to object classification, both in the standard regime of rich training data and in the few-shot scenario, where each category is represented by only a few examples. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Leonid Karlinsky , Joseph Shtok , Sivan Harary , Eli Schwartz , Amit Aides , Rogerio Feris , Raja Giryes , Alex M. Bronstein

Regularization strategies in medical image registration often take a one-size-fits-all approach by imposing uniform constraints across the entire image domain. Yet biological structures are anything but regular. Lacking structural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Ziad Kheil , Soleakhena Ken , Laurent Risser

In recent years, continuous latent space (CLS) and discrete latent space (DLS) deep learning models have been proposed for medical image analysis for improved performance. However, these models encounter distinct challenges. CLS models…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Vandan Gorade , Sparsh Mittal , Debesh Jha , Ulas Bagci

Deep learning has advanced deformable image registration, surpassing traditional optimization-based methods in both accuracy and efficiency. However, learning-based models are widely believed to be sensitive to domain shift, with robustness…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mingzhen Shao , Sarang Joshi

Learning the generalizable feature representation is critical for few-shot image classification. While recent works exploited task-specific feature embedding using meta-tasks for few-shot learning, they are limited in many challenging tasks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Hao Cheng , Yufei Wang , Haoliang Li , Alex C. Kot , Bihan Wen

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Deep learning methods have played a more and more important role in hyperspectral image classification. However, the general deep learning methods mainly take advantage of the information of sample itself or the pairwise information between…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Zhiqiang Gong , Weidong Hu , Xiaoyong Du , Ping Zhong , Panhe Hu
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