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Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Modern optical microscopes are fully motorised; however, transforming them into truly smart systems requires real-time adjustment of acquisition settings in response to detected objects and dynamic biological events. At the core are…

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

The human ability to synchronize the feedback from all their senses inspired recent works in multi-task and multi-modal learning. While these works rely on expensive supervision, our multi-task graph requires only pseudo-labels from expert…

Machine Learning · Computer Science 2021-11-05 Emanuela Haller , Elena Burceanu , Marius Leordeanu

A popular approach to semi-supervised learning proceeds by endowing the input data with a graph structure in order to extract geometric information and incorporate it into a Bayesian framework. We introduce new theory that gives appropriate…

Machine Learning · Statistics 2020-01-14 Nicolas Garcia Trillos , Zachary Kaplan , Thabo Samakhoana , Daniel Sanz-Alonso

The unsupervised segmentation is an increasingly popular topic in biomedical image analysis. The basic idea is to approach the supervised segmentation task as an unsupervised synthesis problem, where the intensity images can be transferred…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Quan Liu , Isabella M. Gaeta , Bryan A. Millis , Matthew J. Tyska , Yuankai Huo

We contribute to the sparsely populated area of unsupervised deep graph matching with application to keypoint matching in images. Contrary to the standard \emph{supervised} approach, our method does not require ground truth correspondences…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Siddharth Tourani , Carsten Rother , Muhammad Haris Khan , Bogdan Savchynskyy

In this paper we propose a nonparametric graphical test based on optimal matching, for assessing the equality of multiple unknown multivariate probability distributions. Our procedure pools the data from the different classes to create a…

This project aims to break down large pathology images into small tiles and then cluster those tiles into distinct groups without the knowledge of true labels, our analysis shows how difficult certain aspects of clustering tumorous and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Mostafa Ibrahim , Kevin Bryson

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Accurate feature matching and correspondence in endoscopic images play a crucial role in various clinical applications, including patient follow-up and rapid anomaly localization through panoramic image generation. However, developing…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Manel Farhat , Achraf Ben-Hamadou

Map-to-map matching is a critical task for aligning spatial data across heterogeneous sources, yet it remains challenging due to the lack of ground truth correspondences, sparse node features, and scalability demands. In this paper, we…

Machine Learning · Computer Science 2026-01-21 Chaolong Ying , Yinan Zhang , Lei Zhang , Jiazhuang Wang , Shujun Jia , Tianshu Yu

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

Quantitative Methods · Quantitative Biology 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

Since most scientific literature data are unlabeled, this makes unsupervised graph-based semantic representation learning crucial. Therefore, an unsupervised semantic representation learning method of scientific literature based on graph…

Information Retrieval · Computer Science 2023-01-31 Hongrui Gao , Yawen Li , Meiyu Liang , Zeli Guan

Autism spectrum disorder (ASD) remains a challenging condition to diagnose effectively and promptly, despite global efforts in public health, clinical screening, and scientific research. Traditional diagnostic methods, primarily reliant on…

Computers and Society · Computer Science 2025-03-11 Nora Fink

Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Mehdi Naouar , Gabriel Kalweit , Ignacio Mastroleo , Philipp Poxleitner , Marc Metzger , Joschka Boedecker , Maria Kalweit

Unsupervised domain adaptation aiming to learn a specific task for one domain using another domain data has emerged to address the labeling issue in supervised learning, especially because it is difficult to obtain massive amounts of…

Machine Learning · Computer Science 2019-03-13 Jaeyoon Yoo , Changhwa Park , Yongjun Hong , Sungroh Yoon

Semi-supervised learning has substantially advanced medical image segmentation since it alleviates the heavy burden of acquiring the costly expert-examined annotations. Especially, the consistency-based approaches have attracted more…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Zhe Xu , Yixin Wang , Donghuan Lu , Lequan Yu , Jiangpeng Yan , Jie Luo , Kai Ma , Yefeng Zheng , Raymond Kai-yu Tong

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen
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