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For decades, the growth and volume of digital data collection has made it challenging to digest large volumes of information and extract underlying structure. Coined 'Big Data', massive amounts of information has quite often been gathered…

Human-Computer Interaction · Computer Science 2016-11-17 Andrew Moran , Vijay Gadepally , Matthew Hubbell , Jeremy Kepner

Rapid growth in scientific data and a widening gap between computational speed and I/O bandwidth makes it increasingly infeasible to store and share all data produced by scientific simulations. Instead, we need methods for reducing data…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-05-28 Jieyang Chen , Lipeng Wan , Xin Liang , Ben Whitney , Qing Liu , Qian Gong , David Pugmire , Nicholas Thompson , Jong Youl Choi , Matthew Wolf , Todd Munson , Ian Foster , Scott Klasky

This paper highlights the rationale for the development of BioViz, a tool to help visualize the existence of collective user interactions in online life science communities. The first community studied has approximately 22,750 unique users…

Social and Information Networks · Computer Science 2012-04-17 Dhiraj Murthy , Alexander Gross , Stephanie Bond

Modern experiments in many disciplines generate large quantities of network (graph) data. Researchers require aesthetic layouts of these networks that clearly convey the domain knowledge and meaning. However, the problem remains challenging…

Human-Computer Interaction · Computer Science 2023-05-23 Aditya Bharadwaj , David Gwizdala , Yoonjin Kim , Kurt Luther , T. M. Murali

We introduce a new dataset, MELINDA, for Multimodal biomEdicaL experImeNt methoD clAssification. The dataset is collected in a fully automated distant supervision manner, where the labels are obtained from an existing curated database, and…

Computation and Language · Computer Science 2020-12-18 Te-Lin Wu , Shikhar Singh , Sayan Paul , Gully Burns , Nanyun Peng

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Rapid growth in scientific data and a widening gap between computational speed and I/O bandwidth make it increasingly infeasible to store and share all data produced by scientific simulations. Instead, we need methods for reducing data…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-02 Jieyang Chen , Lipeng Wan , Xin Liang , Ben Whitney , Qing Liu , David Pugmire , Nicholas Thompson , Matthew Wolf , Todd Munson , Ian Foster , Scott Klasky

Clinicians often face workflow problems that are perceived as either too bespoke or low stakes to attract commercial attention. Historically, most do not have the technical knowledge to address these problems, but the recent emergence of…

Human-Computer Interaction · Computer Science 2026-04-28 Ariel Yuhan Ong , Iain Livingstone , Caroline Kilduff , Mertcan Sevgi , David A Merle , Eden Ruffell , Pearse A Keane , Fares Antaki

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many…

Human-Computer Interaction · Computer Science 2020-06-19 David Borland , Wenyuan Wang , Jonathan Zhang , Joshua Shrestha , David Gotz

Medical image computing software is essential for identifying imaging biomarkers that can support diagnosis, prognosis, treatment planning, and clinical research. However, the lack of standardized, user-friendly, and reproducible software…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Mohammad Salmanpour , Mehrdad Oveisi , Isaac Shiri , Arman Rahmim

In the past decade, deep learning (DL) has achieved unprecedented success in numerous fields including computer vision, natural language processing, and healthcare. In particular, DL is experiencing an increasing development in applications…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Liang Zhang , Johann Li , Ping Li , Xiaoyuan Lu , Peiyi Shen , Guangming Zhu , Syed Afaq Shah , Mohammed Bennarmoun , Kun Qian , Björn W. Schuller

While the biomedical community has published several "open data" sources in the last decade, most researchers still endure severe logistical and technical challenges to discover, query, and integrate heterogeneous data and knowledge from…

Artificial Intelligence · Computer Science 2020-06-09 Maulik R. Kamdar , Mark A. Musen

With the emergence of large language models (LLMs) and AI agent frameworks, the human-AI co-work paradigm known as Vibe Coding is changing how people code, making it more accessible and productive. In scientific research, where workflows…

Artificial Intelligence · Computer Science 2026-04-28 Zihao Wu , Steven Xu , Bowen Chen , Shaowen Wan , Yiwei Li , Wei Ruan , Yanjun Lyu , Siyuan Li , Dajiang Zhu , Tianming Liu , Lin Zhao

For over half a century, the computer mouse has been the primary tool for interacting with digital data, yet it remains a limiting factor in exploring complex, multi-scale scientific images. Traditional 2D visualization methods hinder…

Most bioinformatics pipelines consist of software components that are tightly coupled to the logic of the pipeline itself. This limits reusability of the individual components in the pipeline or introduces maintenance overhead when they…

Software Engineering · Computer Science 2021-10-25 Robrecht Cannoodt , Hendrik Cannoodt , Eric Van de Kerckhove , Andy Boschmans , Dries De Maeyer , Toni Verbeiren

Data scientists across disciplines are increasingly in need of exploratory analysis tools for data sets with a high volume of features of mixed data type (quantitative continuous and discrete categorical). We introduce Sirius, a novel…

Many research groups aspire to make data and code FAIR and reproducible, yet struggle because the data and code life cycles are disconnected, executable environments are often missing from published work, and technical skill requirements…

The amount of scientific papers published every day is daunting and constantly increasing. Keeping up with literature represents a challenge. If one wants to start exploring new topics it is hard to have a big picture without reading lots…

Information Retrieval · Computer Science 2020-11-10 Alberto Calderone

Machine learning models often learn latent embedding representations that capture the domain semantics of their training data. These embedding representations are valuable for interpreting trained models, building new models, and analyzing…

Machine Learning · Computer Science 2023-06-16 Zijie J. Wang , Fred Hohman , Duen Horng Chau

Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualizing information derived from biological microscopy imaging data. In the past decade, we observed a dramatic increase…

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