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The Segment Anything Model (SAM) exhibits remarkable versatility and zero-shot learning abilities, owing largely to its extensive training data (SA-1B). Recognizing SAM's dependency on manual guidance given its category-agnostic nature, we…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Xiyu Qi , Yifan Wu , Yongqiang Mao , Wenhui Zhang , Yidan Zhang

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Deep neural networks often suffer from poor generalization caused by complex and non-convex loss landscapes. One of the popular solutions is Sharpness-Aware Minimization (SAM), which smooths the loss landscape via minimizing the maximized…

Machine Learning · Computer Science 2022-10-25 Peng Mi , Li Shen , Tianhe Ren , Yiyi Zhou , Xiaoshuai Sun , Rongrong Ji , Dacheng Tao

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Purpose: Accurate tumor segmentation is vital for adaptive radiation therapy (ART) but remains time-consuming and user-dependent. Segment Anything Model 2 (SAM2) shows promise for prompt-based segmentation but struggles with tumor accuracy.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Guoping Xu , Yan Dai , Hengrui Zhao , Ying Zhang , Jie Deng , Weiguo Lu , You Zhang

The Segment Anything Model (SAM) has recently demonstrated significant potential in medical image segmentation. Although SAM is primarily trained on 2D images, attempts have been made to apply it to 3D medical image segmentation. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Fangda Chen , Jintao Tang , Pancheng Wang , Ting Wang , Shasha Li , Ting Deng

Open-vocabulary semantic segmentation aims to assign pixel-level labels to images across an unlimited range of classes. Traditional methods address this by sequentially connecting a powerful mask proposal generator, such as the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Minhyeok Lee , Suhwan Cho , Jungho Lee , Sunghun Yang , Heeseung Choi , Ig-Jae Kim , Sangyoun Lee

Precision medicine, such as patient-adaptive treatments assisted by medical image analysis, poses new challenges for segmentation algorithms in adapting to new patients, due to the large variability across different patients and the limited…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Chenhui Zhao , Liyue Shen

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Large Language Models (LLMs) are scaling rapidly, creating significant challenges for collaborative server client distributed training, particularly in terms of communication efficiency and computational overheads. To address these…

Machine Learning · Computer Science 2025-10-08 Yurun Song , Zhuoyi Yang , Ian G. Harris , Sangeetha Abdu Jyothi

Nuclei instance segmentation is critical in computational pathology for cancer diagnosis and prognosis. Recently, the Segment Anything Model has demonstrated exceptional performance in various segmentation tasks, leveraging its rich priors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jingze Su , Tianle Zhu , Jiaxin Cai , Zhiyi Wang , Qi Li , Xiao Zhang , Tong Tong , Shu Wang , Wenxi Liu

Recently, foundation models trained on massive datasets to adapt to a wide range of tasks have attracted considerable attention and are actively being explored within the computer vision community. Among these, the Segment Anything Model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Hyung-Il Kim , Kimin Yun , Jun-Seok Yun , Yuseok Bae

Segment Anything Model (SAM) has attracted widespread attention for its superior interactive segmentation capabilities with visual prompts while lacking further exploration of text prompts. In this paper, we empirically investigate what…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Yuxuan Zhang , Tianheng Cheng , Lianghui Zhu , Rui Hu , Lei Liu , Heng Liu , Longjin Ran , Xiaoxin Chen , Wenyu Liu , Xinggang Wang

Segment anything model (SAM) has shown its spectacular performance in segmenting universal objects, especially when elaborate prompts are provided. However, the drawback of SAM is twofold. On the first hand, it fails to segment specific…

Computer Vision and Pattern Recognition · Computer Science 2023-11-16 Leiping Jie , Hui Zhang

The interactive segmentation task consists in the creation of object segmentation masks based on user interactions. The most common way to guide a model towards producing a correct segmentation consists in clicks on the object and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Robin Schön , Julian Lorenz , Katja Ludwig , Rainer Lienhart

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

Recently, Meta AI Research approaches a general, promptable Segment Anything Model (SAM) pre-trained on an unprecedentedly large segmentation dataset (SA-1B). Without a doubt, the emergence of SAM will yield significant benefits for a wide…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Wei Ji , Jingjing Li , Qi Bi , Tingwei Liu , Wenbo Li , Li Cheng

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

Segment Anything Model 2 (SAM2) demonstrated impressive zero-shot capabilities on natural images but faces challenges in biomedical segmentation due to significant domain shifts and prompt dependency. To address these limitations, we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Hinako Mitsuoka , Kazuhiro Hotta
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