English
Related papers

Related papers: Heterogeneous gene network estimation for single-c…

200 papers

Recent work has developed Bayesian methods for the automatic statistical analysis and description of single time series as well as of homogeneous sets of time series data. We extend prior work to create an interpretable kernel embedding for…

Machine Learning · Computer Science 2019-08-27 Andre T. Nguyen , Edward Raff

Estimating heterogeneous treatment effect is an important task in causal inference with wide application fields. It has also attracted increasing attention from machine learning community in recent years. In this work, we reinterpret the…

Methodology · Statistics 2018-10-26 Ran Chen , Hanzhong Liu

Heterogeneous graph neural networks (HGNNs) have powerful capability to embed rich structural and semantic information of a heterogeneous graph into node representations. Existing HGNNs inherit many mechanisms from graph neural networks…

Machine Learning · Computer Science 2023-09-04 Xiaocheng Yang , Mingyu Yan , Shirui Pan , Xiaochun Ye , Dongrui Fan

Feature representation is an important aspect of remote-sensing based image classification. While deep convolutional neural networks are able to effectively amalgamate information, large numbers of parameters often make learned features…

Machine Learning · Computer Science 2022-03-07 Joshua Peeples , Sarah Walker , Connor McCurley , Alina Zare , James Keller , Weihuang Xu

A connectional brain template (CBT) is a normalized graph-based representation of a population of brain networks also regarded as an average connectome. CBTs are powerful tools for creating representative maps of brain connectivity in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-29 Mustafa Burak Gurbuz , Islem Rekik

Network theory has proven invaluable in unraveling complex protein interactions. Previous studies have employed statistical methods rooted in network theory, including the Gaussian graphical model, to infer networks among proteins,…

Methodology · Statistics 2026-05-07 Seungjun Ahn , Eun Jeong Oh

Ultra high-throughput sequencing of transcriptomes (RNA-Seq) is a widely used method for quantifying gene expression levels due to its low cost, high accuracy and wide dynamic range for detection. However, the nature of RNA-Seq makes it…

Methodology · Statistics 2016-08-30 Hui Jiang , Tianyu Zhan

Recently, Deep Convolutional Neural Networks (DCNNs) including the ResNet-20 architecture have been privately evaluated on encrypted, low-resolution data with the Residue-Number-System Cheon-Kim-Kim-Song (RNS-CKKS) homomorphic encryption…

Cryptography and Security · Computer Science 2024-01-30 Vivian Maloney , Richard F. Obrecht , Vikram Saraph , Prathibha Rama , Kate Tallaksen

Single-cell sequencing has a significant role to explore biological processes such as embryonic development, cancer evolution, and cell differentiation. These biological properties can be presented by a two-dimensional scatter plot.…

Genomics · Quantitative Biology 2021-10-19 Ziyi Liu , Minghui Liao , Fulin luo , Bo Du

Precise crop yield prediction is essential for improving agricultural practices and ensuring crop resilience in varying climates. Integrating weather data across the growing season, especially for different crop varieties, is crucial for…

Machine Learning · Computer Science 2023-09-25 Zahra Khalilzadeh , Motahareh Kashanian , Saeed Khaki , Lizhi Wang

The genomic reality is a highly complex and dynamic system. The recent development of high-throughput technologies has enabled researchers to measure the abundance of many genes (in the order of thousands) simultaneously. The challenge is…

Applications · Statistics 2013-10-08 Anani Lotsi , Ernst Wit

Network-based analyses of high-throughput genomics data provide a holistic, systems-level understanding of various biological mechanisms for a common population. However, when estimating multiple networks across heterogeneous…

Biomedical sciences are increasingly recognising the relevance of gene co-expression-networks for analysing complex-systems, phenotypes or diseases. When the goal is investigating complex-phenotypes under varying conditions, it comes…

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

Kernel methods are powerful tools to capture nonlinear patterns behind data. They implicitly learn high (even infinite) dimensional nonlinear features in the Reproducing Kernel Hilbert Space (RKHS) while making the computation tractable by…

Machine Learning · Statistics 2017-11-28 Shuai Zhang , Jianxin Li , Pengtao Xie , Yingchun Zhang , Minglai Shao , Haoyi Zhou , Mengyi Yan

With the rising prevalence of cardiovascular diseases, electrocardiograms (ECG) remain essential for the non-invasive detection of cardiac abnormalities. This study presents a comprehensive evaluation of deep neural network architectures…

Signal Processing · Electrical Eng. & Systems 2026-02-23 Yun Song , Wenjia Zheng , Tiedan Chen , Ziyu Wang , Jiazhao Shi , Yisong Chen

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificities. Existing methods fall into three classes: Some are based on Convolutional Neural Networks (CNNs), others use…

Machine Learning · Computer Science 2019-01-31 Ameni Trabelsi , Mohamed Chaabane , Asa Ben Hur

Deep neural networks (DNNs) have made a revolution in numerous fields during the last decade. However, in tasks with high safety requirements, such as medical or autonomous driving applications, providing an assessment of the models…

Machine Learning · Computer Science 2020-11-20 Omer Achrack , Raizy Kellerman , Ouriel Barzilay

We develop novel hierarchical reciprocal graphical models to infer gene networks from heterogeneous data. In the case of data that can be naturally divided into known groups, we propose to connect graphs by introducing a hierarchical prior…

Methodology · Statistics 2018-01-23 Yang Ni , Peter Mueller , Yitan Zhu , Yuan Ji

Real networks often have severe degree heterogeneity, with the maximum, average, and minimum node degrees differing significantly. This paper examines the impact of degree heterogeneity on statistical limits of network data analysis.…

Statistics Theory · Mathematics 2024-07-24 Zheng Tracy Ke , Jingming Wang