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Noninvasive brain stimulation can write signals into neurons but requires power electronics with exceptionally high power in the mega-volt-ampere range and kilohertz usable bandwidth. Whereas oscillator circuits offered only one or very few…

Systems and Control · Electrical Eng. & Systems 2025-09-03 Jinshui Zhang , Stefan M. Goetz

The temporal shape of a pulse in transcranial magnetic stimulation (TMS) influences which neuron populations are activated preferentially as well as the strength and even direction of neuromodulation effects. Furthermore, various pulse…

Medical Physics · Physics 2022-02-15 Z. Li , J. Zhang , A. V. Peterchev , S. M. Goetz

Transcranial magnetic stimulation (TMS) with asymmetric electric field pulses, such as monophasic, offers directional selectivity for neural activation but requires excessive energy. Previous pulse shape optimisation has been limited to…

Magnetic stimulation is a standard tool in brain research and many fields of neurology, as well as psychiatry. From a physical perspective, one key aspect of this method is the inefficiency of available setups. Whereas the spatial field…

Medical Physics · Physics 2011-06-20 Stefan M. Goetz , Nam C. Truong , Manuel G. Gerhofer , Thomas Weyh , Hans-Georg Herzog

The interaction of coherent nonlinear structures (such as sub-cycle solitons, electron vortices and wake Langmuir waves) with a strong wake wave in a collisionless plasma can be exploited in order to produce ultra-short electromagnetic…

Plasma Physics · Physics 2009-11-11 S. S. Bulanov , T. Zh. Esirkepov , F. F. Kamenets , F. Pegoraro

We theoretically demonstrate the possibility to tune the temporal waveform of optical unipolar pulses upon their coherent interaction with a multi-level resonant medium. This is achieved through the coherent control of the response of a…

Improving resolution and sensitivity will widen possible medical applications of magnetic particle imaging. Pulsed excitation promises such benefits, at the cost of more complex hardware solutions and restrictions on drive field amplitude…

A new type of non-invasive deep-brain stimulation is conceived and demonstrated by computer simulations. The process is based on spatio-temporal Fourier synthesis using multiple electrode pairs with sinusoidal current drive to limit skin…

General Physics · Physics 2024-08-02 Laszlo B. Kish , Andrea Antal

Transmission through photoexcited semiconductors is used to temporally and spectrally shape a Terahertz pulse. By adjusting the optical pump-THz probe delay, we experimentally introduce a polar asymmetry in the pulse profile as high as 92%.…

Opto-mechanical oscillators that generate coherent acoustic waves are drawing much interest, in both fundamental research and applications. Narrowband oscillations can be obtained through the introduction of feedback to the acoustic wave.…

Optics · Physics 2018-11-16 H. Hagai Diamandi , Yosef London , Gil Bashan , Arik Bergman , Avi Zadok

Long-lived (symmetry protected) hyperpolarized spin states offer important new opportunities (for example, in clinical MR imaging), but existing methods for producing these states are limited by either excess energy dissipation or high…

Chemical Physics · Physics 2015-06-17 Thomas Theis , Yesu Feng , Tung-Lin Wu , Warren S. Warren

Multimode fibers (MMFs) have recently reemerged as attractive avenues for nonlinear effects due to their high-dimensional spatiotemporal nonlinear dynamics and scalability for high power. High-brightness MMF sources with effective control…

Optics · Physics 2023-12-07 Tong Qiu , Honghao Cao , Kunzan Liu , Li-Yu Yu , Manuel Levy , Eva Lendaro , Fan Wang , Sixian You

We present a novel methodology to enable control of a neuromorphic circuit in close analogy with the physiological neuromodulation of a single neuron. The methodology is general in that it only relies on a parallel interconnection of…

Neurons and Cognition · Quantitative Biology 2020-11-19 Luka Ribar , Rodolphe Sepulchre

We study optical response of a resonant medium possessing nonlinear coupling to external field driven by a few-cycle pump pulse sequence. We demonstrate the possibility to directly produce unipolar half-cycle pulses from the medium…

Hyperpolarization methods in magnetic resonance overcome sensitivity limitations, especially for low-{\gamma} nuclei such as 13C and 15N. Signal Amplification By Reversible Exchange (SABRE) and extended SABRE (X-SABRE) are efficient and…

Chemical Physics · Physics 2022-04-06 Jacob R. Lindale , Shannon L. Eriksson , Warren S. Warren

Conventional time-modulated arrays are based on the application of variable-width periodical rectangular pulses (easily implemented with radio frequency switches) to the individual antenna excitations. However, a serious bottleneck arises…

Signal Processing · Electrical Eng. & Systems 2024-01-30 R. Maneiro-Catoira , J. Brégains , José A. García-Naya , L. Castedo

In this article, we design a novel Transcranial Electrical Stimulator for medical applications, which is very cheap and can produce the desired signals very accurately. Our fabricated stimulator generates all current signals related to…

Signal Processing · Electrical Eng. & Systems 2020-09-10 HoseinAli Jafari , Mohammad Bagher Heydari , Niloofar Jafari , Hamid Mirhosseini

Brain dynamics can exhibit narrow-band nonlinear oscillations and multistability. For a subset of disorders of consciousness and motor control, we hypothesize that some symptoms originate from the inability to spontaneously transition from…

Neurons and Cognition · Quantitative Biology 2020-06-24 Ian D. Jordan , Il Memming Park

The traditional method to generate pulses in the range of some nanoseconds with high amplitudes, is the using of the avalanche-effect of transistors. However the problem with this method is the poor possibility for parameterizing. That was…

Instrumentation and Detectors · Physics 2013-12-03 Franz Peter Zantis

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage…

Neurons and Cognition · Quantitative Biology 2012-10-05 Tao Hu , Dmitri B. Chklovskii
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