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Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Medical Physics · Physics 2024-11-14 R. M. Winter , O. Engelsen , O. J. Bratting , N. Brekke , J. Sæterstøl , O. Sæther , K. R. Redalen

Medical steerable needles can follow 3D curvilinear trajectories inside body tissue, enabling them to move around critical anatomical structures and precisely reach clinically significant targets in a minimally invasive way. Automating…

Robotics · Computer Science 2022-03-01 Mengyu Fu , Kiril Solovey , Oren Salzman , Ron Alterovitz

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and…

Medical Physics · Physics 2025-12-10 Chahrazed Ghannoudi , Marie-Claude Lavallee , Benjamin Cote , Luc Beaulieu

A biopsy is the only diagnostic procedure for accurate histological confirmation of breast cancer. When sonographic placement is not feasible, a Magnetic Resonance Imaging(MRI)-guided biopsy is often preferred. The lack of real-time imaging…

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

Medical Physics · Physics 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen

In this paper knowledge based planning has been revolutionized via a novel mathematical model which converts three dimensional dose distribution (3D3) prediction to a clinical utilizable IMRT treatment plan. Presented model has benefited…

Optimization and Control · Mathematics 2022-06-14 Ali Yousefi , Saeedeh Ketabi , Iraj Abedi

Estimating 3D hand meshes from single RGB images is challenging, due to intrinsic 2D-3D mapping ambiguities and limited training data. We adopt a compact parametric 3D hand model that represents deformable and articulated hand meshes. To…

Computer Vision and Pattern Recognition · Computer Science 2019-04-10 Seungryul Baek , Kwang In Kim , Tae-Kyun Kim

Computed Tomography (CT) image guidance enables accurate and safe minimally invasive treatment of diseases, including cancer and chronic pain, with needle-like tools via a percutaneous approach. The physician incrementally inserts and…

To treat Trochlear Dysplasia (TD), current approaches rely mainly on low-resolution clinical Magnetic Resonance (MR) scans and surgical intuition. The surgeries are planned based on surgeons experience, have limited adoption of minimally…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Michael Wehrli , Alicia Durrer , Paul Friedrich , Sidaty El Hadramy , Edwin Li , Luana Brahaj , Carol C. Hasler , Philippe C. Cattin

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

Medical Physics · Physics 2019-09-04 Rodney D. Wiersma , Xinmin Liu

In this paper we describe a new robotic brachytherapy needle-insertion system that is designed to replace the template used in the manual technique. After a brief review of existing robotic systems, we describe the requirements that we…

Robotics · Computer Science 2009-09-15 Nikolai Hungr , Jocelyne Troccaz , Nabil Zemiti , Nathanael Tripodi

Purpose: This study aimed to use deep learning-based dose prediction to assess head and neck (HN) plan quality and identify suboptimal plans. Methods: A total of 245 VMAT HN plans were created using RapidPlan knowledge-based planning (KBP).…

Head and neck (H&N) cancers are among the most prevalent types of cancer worldwide, and [18F]F-FDG PET/CT is widely used for H&N cancer management. Recently, the diffusion model has demonstrated remarkable performance in various…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Yafei Dong , Kuang Gong

In this work, we propose a Machine Learning model that generates an adjustable 3D dose distribution for external beam radiation therapy for head-and-neck cancer treatments. In contrast to existing Machine Learning methods that provide a…

Cervical cancer accounts for a significant portion of the global cancer burden among women. Interstitial brachytherapy (ISBT) is a standard procedure for treating cervical cancer; it involves placing a radioactive source through a straight…

External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Shane Farrar , Erik Leon

The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the…

Medical Physics · Physics 2019-03-27 Dan Nguyen , Xun Jia , David Sher , Mu-Han Lin , Zohaib Iqbal , Hui Liu , Steve Jiang