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Machine learning based methods have shown potential for optimizing existing molecules with more desirable properties, a critical step towards accelerating new chemical discovery. Here we propose QMO, a generic query-based molecule…

Machine Learning · Computer Science 2022-04-21 Samuel Hoffman , Vijil Chenthamarakshan , Kahini Wadhawan , Pin-Yu Chen , Payel Das

In the majority of molecular optimization tasks, predictive machine learning (ML) models are limited due to the unavailability and cost of generating big experimental datasets on the specific task. To circumvent this limitation, ML models…

Quantum computing is greatly advanced in recent years and is expected to transform the computation paradigm in the near future. Quantum circuit simulation plays a key role in the toolchain for the development of quantum hardware and…

Emerging Technologies · Computer Science 2020-07-21 Yuan-Hung Tsai , Jie-Hong R. Jiang , Chiao-Shan Jhang

Quantum neural networks are promising for a wide range of applications in the Noisy Intermediate-Scale Quantum era. As such, there is an increasing demand for automatic quantum neural architecture search. We tackle this challenge by…

Quantum Physics · Physics 2023-12-06 Trong Duong , Sang T. Truong , Minh Tam , Bao Bach , Ju-Young Ryu , June-Koo Kevin Rhee

The quantum circuit layout (QCL) problem is to map a quantum circuit such that the constraints of the device are satisfied. We introduce a quantum circuit mapping heuristic, QXX, and its machine learning version, QXX-MLP. The latter infers…

Quantum Physics · Physics 2022-09-27 Alexandru Paler , Lucian M. Sasu , Adrian Florea , Razvan Andonie

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

Quantum computational chemistry holds great promise for simulating molecular systems more efficiently than classical methods by leveraging quantum bits to represent molecular wavefunctions. However, current implementations face significant…

Quantum Physics · Physics 2025-09-10 Weitang Li , Shi-Xin Zhang , Zirui Sheng , Cunxi Gong , Jianpeng Chen , Zhigang Shuai

We propose an efficient protocol for digital quantum simulation of quantum chemistry problems and enhanced digital-analog quantum simulation of transport phenomena in biomolecules with superconducting circuits. Along these lines, we…

Quantum Physics · Physics 2016-06-23 L. García-Álvarez , U. Las Heras , A. Mezzacapo , M. Sanz , E. Solano , L. Lamata

Quantum machine learning algorithms have emerged to be a promising alternative to their classical counterparts as they leverage the power of quantum computers. Such algorithms have been developed to solve problems like electronic structure…

Chemical Physics · Physics 2021-10-29 Manas Sajjan , Shree Hari Sureshbabu , Sabre Kais

Parametrized quantum circuits are essential components of variational quantum algorithms. Until now, optical implementations of these circuits have relied solely on adjustable linear optical units. In this study, we demonstrate that using…

Quantum Physics · Physics 2025-01-22 E. A. Chernykh , M. Yu. Saygin , G. I. Struchalin , S. P. Kulik , S. S. Straupe

Efficient quantum circuit optimization schemes are central to quantum simulation of strongly interacting quantum many body systems. Here, we present an optimization algorithm which combines machine learning techniques and tensor network…

Quantum Physics · Physics 2024-08-23 David Rogerson , Ananda Roy

Quantum variational circuits have gained significant attention due to their applications in the quantum approximate optimization algorithm and quantum machine learning research. This work introduces a novel class of classical probabilistic…

Quantum Physics · Physics 2025-09-17 Gal Weitz , Lirandë Pira , Chris Ferrie , Joshua Combes

Quantum mechanics has introduced a new theoretical framework for the study of molecules, enabling the prediction of properties and dynamics through the solution of the Schr\"odinger equation applied to these systems. However, solving this…

Recent advancements in quantum computing (QC) and machine learning (ML) have garnered significant attention, leading to substantial efforts toward the development of quantum machine learning (QML) algorithms to address a variety of complex…

Quantum Physics · Physics 2024-12-18 Samuel Yen-Chi Chen

A new concept of the molecular structure optimization method based on quantum dynamics computations is presented. Nuclei are treated as quantum mechanical particles, as are electrons, and the many-body wave function of the system is…

Quantum computing has shown tremendous promise in addressing complex computational problems, yet its practical realization is hindered by the limited availability of qubits for computation. Recent advancements in quantum hardware have…

Quantum Physics · Physics 2023-11-22 Kun Fang , Munan Zhang , Ruqi Shi , Yinan Li

A central task in the field of quantum computing is to find applications where quantum computer could provide exponential speedup over any classical computer. Machine learning represents an important field with broad applications where…

Quantum Physics · Physics 2017-11-07 Xun Gao , Zhengyu Zhang , Luming Duan

In a recent preprint by Deutsch et al. [1995] the authors suggest the possibility of polynomial approximability of arbitrary unitary operations on $n$ qubits by 2-qubit unitary operations. We address that comment by proving strong lower…

Quantum Physics · Physics 2008-02-03 E. Knill

When the electric conductance of a nano-sized metal is measured at low temperatures, it often exhibits complex but reproducible patterns as a function of external magnetic fields, called quantum fingerprints in electric conductance. Such…

Mesoscale and Nanoscale Physics · Physics 2022-06-14 Shunsuke Daimon , Kakeru Tsunekawa , Shinji Kawakami , Takashi Kikkawa , Rafael Ramos , Koichi Oyanagi , Tomi Ohtsuki , Eiji Saitoh

This article gives an overview and a perspective of recent theoretical proposals and their experimental implementations in the field of quantum machine learning. Without an aim to being exhaustive, the article reviews specific high-impact…

Quantum Physics · Physics 2023-05-03 Lucas Lamata