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Medical image segmentation modeling is a high-stakes task where understanding of uncertainty is crucial for addressing visual ambiguity. Prior work has developed segmentation models utilizing probabilistic or generative mechanisms to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Andre Ye , Quan Ze Chen , Amy Zhang

Segmentation is a fundamental task in medical image analysis. The clinical interest is often to measure the volume of a structure. To evaluate and compare segmentation methods, the similarity between a segmentation and a predefined ground…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 Jeroen Bertels , David Robben , Dirk Vandermeulen , Paul Suetens

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Despite the superior performance of Deep Learning (DL) on numerous segmentation tasks, the DL-based approaches are notoriously overconfident about their prediction with highly polarized label probability. This is often not desirable for…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Sungmin Hong , Anna K. Bonkhoff , Andrew Hoopes , Martin Bretzner , Markus D. Schirmer , Anne-Katrin Giese , Adrian V. Dalca , Polina Golland , Natalia S. Rost

In ill-posed imaging inverse problems, uncertainty quantification remains a fundamental challenge, especially in safety-critical applications. Recently, conformal prediction has been used to quantify the uncertainty that the inverse problem…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Jeffrey Wen , Rizwan Ahmad , Philip Schniter

Each year, numerous segmentation and classification algorithms are invented or reused to solve problems where machine vision is needed. Generally, the efficiency of these algorithms is compared against the results given by one or many human…

Computer Vision and Pattern Recognition · Computer Science 2008-12-18 Arnaud Martin , Hicham Laanaya , Andreas Arnold-Bos

In real-world settings involving consequential decision-making, the deployment of machine learning systems generally requires both reliable uncertainty quantification and protection of individuals' privacy. We present a framework that…

Machine Learning · Computer Science 2024-03-05 Anastasios N. Angelopoulos , Stephen Bates , Tijana Zrnic , Michael I. Jordan

Learning-based lossless image compression employs pixel-based or subimage-based auto-regression for probability estimation, which achieves desirable performances. However, the existing works only consider context dependencies in one…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Tiantian Li , Qunbing Xia , Yue Li , Ruixiao Guo , Gaobo Yang

Denoising Diffusion Probabilistic models have become increasingly popular due to their ability to offer probabilistic modeling and generate diverse outputs. This versatility inspired their adaptation for image segmentation, where multiple…

Almost all existing amodal segmentation methods make the inferences of occluded regions by using features corresponding to the whole image. This is against the human's amodal perception, where human uses the visible part and the shape prior…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Yuting Xiao , Yanyu Xu , Ziming Zhong , Weixin Luo , Jiawei Li , Shenghua Gao

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Predictive inference is a fundamental task in statistics, traditionally addressed using parametric assumptions about the data distribution and detailed analyses of how models learn from data. In recent years, conformal prediction has…

Methodology · Statistics 2026-03-26 Matteo Sesia , Stefano Favaro

Amodal segmentation aims to predict segmentation masks for both the visible and occluded regions of an object. Most existing works formulate this as a supervised learning problem, requiring manually annotated amodal masks or synthetic…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Jae Joong Lee , Bedrich Benes , Raymond A. Yeh

The elliptical shape prior information plays a vital role in improving the accuracy of image segmentation for specific tasks in medical and natural images. Existing deep learning-based segmentation methods, including the Segment Anything…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Xinyu Zhao , Jun Liu , Faqiang Wang , Li Cui , Yuping Duan

Conformal prediction is a general distribution-free approach for constructing prediction sets combined with any machine learning algorithm that achieve valid marginal or conditional coverage in finite samples. Ordinal classification is…

Methodology · Statistics 2024-11-05 Subhrasish Chakraborty , Chhavi Tyagi , Haiyan Qiao , Wenge Guo

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Kovvuri Sai Gopal Reddy , Bodduluri Saran , A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

Conformal prediction is a statistically rigorous method for quantifying uncertainty in models by having them output sets of predictions, with larger sets indicating more uncertainty. However, prediction sets are not inherently actionable;…

Machine Learning · Computer Science 2025-02-17 Jesse C. Cresswell , Bhargava Kumar , Yi Sui , Mouloud Belbahri

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Uncertainty in medical image segmentation is inherently non-uniform, with boundary regions exhibiting substantially higher ambiguity than interior areas. Conventional training treats all pixels equally, leading to unstable optimization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jinming Zhang , Youpeng Yang , Xi Yang , Haosen Shi , Yuyao Yan , Qiufeng Wang , Guangliang Cheng , Kaizhu Huang
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