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Multimodal Large Language Models (MLLMs) have shown strong potential for radiology report generation, yet their clinical translation is hindered by architectural heterogeneity and the prevalence of factual hallucinations. Standard…

Machine Learning · Computer Science 2026-01-13 Kun Zhao , Siyuan Dai , Pan Wang , Jifeng Song , Hui Ji , Chenghua Lin , Liang Zhan , Haoteng Tang

Nearly all human work is collaborative; thus, the evaluation of real-world NLP applications often requires multiple dimensions that align with diverse human perspectives. As real human evaluator resources are often scarce and costly, the…

Computation and Language · Computer Science 2025-07-29 Jiaju Chen , Yuxuan Lu , Xiaojie Wang , Huimin Zeng , Jing Huang , Jiri Gesi , Ying Xu , Bingsheng Yao , Dakuo Wang

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Autonomous coding agents built on large language models (LLMs) can now solve many general software and machine learning tasks, but they remain ineffective on complex, domain-specific scientific problems. Medical imaging is a particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Roshan Kenia , Xiaoman Zhang , Pranav Rajpurkar

The evaluation of large language models is a complex task, in which several approaches have been proposed. The most common is the use of automated benchmarks in which LLMs have to answer multiple-choice questions of different topics.…

Artificial Intelligence · Computer Science 2025-07-18 Carlos Arriaga , Gonzalo Martínez , Eneko Sendin , Javier Conde , Pedro Reviriego

Reliable extraction of structured data from radiology reports using Large Language Models (LLMs) remains challenging, especially for complex, non-English texts like Hebrew. This study introduces an agent-based uncertainty-aware approach to…

Computation and Language · Computer Science 2025-02-05 Hadas Ben-Atya , Naama Gavrielov , Zvi Badash , Gili Focht , Ruth Cytter-Kuint , Talar Hagopian , Dan Turner , Moti Freiman

Automatic medical report generation can greatly reduce the workload of doctors, but it is often unreliable for real-world deployment. Current methods can write formally fluent sentences but may be factually flawed, introducing serious…

Computational Engineering, Finance, and Science · Computer Science 2025-12-03 Yuan Wang , Shujian Gao , Jiaxiang Liu , Songtao Jiang , Haoxiang Xia , Xiaotian Zhang , Zhaolu Kang , Yemin Wang , Zuozhu Liu

Multiple myeloma is managed through sequential lines of therapy over years to decades, with each decision depending on cumulative disease history distributed across dozens to hundreds of heterogeneous clinical documents. Whether LLM-based…

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

We introduce RadA-BenchPlat, an evaluation platform that benchmarks the performance of large language models (LLMs) act as agent cores in radiology environments using 2,200 radiologist-verified synthetic patient records covering six…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Qiaoyu Zheng , Chaoyi Wu , Pengcheng Qiu , Lisong Dai , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Language Models (LLMs) have been reported to outperform existing automatic evaluation metrics in some tasks, such as text summarization and machine translation. However, there has been a lack of research on LLMs as evaluators in…

Computation and Language · Computer Science 2024-05-28 Masamune Kobayashi , Masato Mita , Mamoru Komachi

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

In radiology, Artificial Intelligence (AI) has significantly advanced report generation, but automatic evaluation of these AI-produced reports remains challenging. Current metrics, such as Conventional Natural Language Generation (NLG) and…

Computation and Language · Computer Science 2024-02-20 Qingqing Zhu , Xiuying Chen , Qiao Jin , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Xin Gao , Ronald M Summers , Zhiyong Lu

Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

Computation and Language · Computer Science 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

We propose a new automated evaluation metric for machine-generated radiology reports using the successful COMET architecture adapted for the radiology domain. We train and publish four medically-oriented model checkpoints, including one…

Computation and Language · Computer Science 2023-11-29 Amos Calamida , Farhad Nooralahzadeh , Morteza Rohanian , Koji Fujimoto , Mizuho Nishio , Michael Krauthammer

As multimodal LLM-driven agents advance in autonomy and generalization, traditional static datasets face inherent scalability limitations and are insufficient for fully assessing their capabilities in increasingly complex and diverse tasks.…

Computation and Language · Computer Science 2026-03-06 Yurun Chen , Xavier Hu , Yuhan Liu , Ziqi Wang , Zeyi Liao , Lin Chen , Feng Wei , Yuxi Qian , Bo Zheng , Keting Yin , Shengyu Zhang

Large language models (LLMs) have saturated standard medical benchmarks that test factual recall, yet their ability to perform higher-order reasoning, such as synthesizing evidence from multiple sources, remains critically under-explored.…

Computation and Language · Computer Science 2026-05-12 Huy Hoang Ha , Benoit Favre , Francois Portet
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