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Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Digital pathology based on whole slide images (WSIs) plays a key role in cancer diagnosis and clinical practice. Due to the high resolution of the WSI and the unavailability of patch-level annotations, WSI classification is usually…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Litao Yang , Deval Mehta , Sidong Liu , Dwarikanath Mahapatra , Antonio Di Ieva , Zongyuan Ge

Automated characterization of spatial data is a kind of critical geographical intelligence. As an emerging technique for characterization, Spatial Representation Learning (SRL) uses deep neural networks (DNNs) to learn non-linear embedded…

Machine Learning · Computer Science 2021-09-24 Dongjie Wang , Kunpeng Liu , David Mohaisen , Pengyang Wang , Chang-Tien Lu , Yanjie Fu

Medical image classification is a challenging task due to the scarcity of labeled samples and class imbalance caused by the high variance in disease prevalence. Semi-supervised learning (SSL) methods can mitigate these challenges by…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Md Junaid Mahmood , Pranaw Raj , Divyansh Agarwal , Suruchi Kumari , Pravendra Singh

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

Self-supervised learning (SSL) has achieved remarkable performance in various medical imaging tasks by dint of priors from massive unlabelled data. However, regarding a specific downstream task, there is still a lack of an instruction book…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Chuyan Zhang , Yun Gu

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

While challenging, the dense segmentation of histology images is a necessary first step to assess changes in tissue architecture and cellular morphology. Although specific convolutional neural network architectures have been applied with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Korsuk Sirinukunwattana , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Image-level weakly-supervised semantic segmentation (WSSS) reduces the usually vast data annotation cost by surrogate segmentation masks during training. The typical approach involves training an image classification network using global…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Arvi Jonnarth , Yushan Zhang , Michael Felsberg

Multiple Instance Learning (MIL) models have proven effective for cancer prognosis from Whole Slide Images. However, the original MIL formulation incorrectly assumes the patches of the same image to be independent, leading to a loss of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Thiziri Nait Saada , Valentina Di Proietto , Benoit Schmauch , Katharina Von Loga , Lucas Fidon

Collecting large-scale medical datasets with fully annotated samples for training of deep networks is prohibitively expensive, especially for 3D volume data. Recent breakthroughs in self-supervised learning (SSL) offer the ability to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Duy M. H. Nguyen , Hoang Nguyen , Mai T. N. Truong , Tri Cao , Binh T. Nguyen , Nhat Ho , Paul Swoboda , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Self-supervised learning (SSL) has demonstrated its effectiveness in learning representations through comparison methods that align with human intuition. However, mainstream SSL methods heavily rely on high body datasets with single label,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Jiale Chen

Representation learning of pathology whole-slide images (WSIs) has primarily relied on weak supervision with Multiple Instance Learning (MIL). This approach leads to slide representations highly tailored to a specific clinical task.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Tim Lenz , Peter Neidlinger , Marta Ligero , Georg Wölflein , Marko van Treeck , Jakob Nikolas Kather

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Integrating front-end speech enhancement (SE) models with self-supervised learning (SSL)-based speech models is effective for downstream tasks in noisy conditions. SE models are commonly fine-tuned using SSL representations with mean…

Computation and Language · Computer Science 2026-01-30 Amit Meghanani , Thomas Hain

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Recent successes in self-supervised learning (SSL) model spatial co-occurrences of visual features either by masking portions of an image or by aggressively cropping it. Here, we propose a new way to model spatial co-occurrences by aligning…

Machine Learning · Computer Science 2025-01-07 Arthur Aubret , Céline Teulière , Jochen Triesch