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Digital pathology has fundamentally altered diagnostic workflows by enabling the computational analysis of gigapixel Whole Slide Images (WSIs), yet effectively deciphering their complex tumor microenvironments remains a formidable…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuemei Qiu , Dawei Fan , Yebin Huang , Yanping Chen , Lifang Wei

Large medical imaging datasets can be cheaply and quickly annotated with low-confidence, weak labels (e.g., radiological scores). Access to high-confidence labels, such as histology-based diagnoses, is rare and costly. Pretraining…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Emma Sarfati , Alexandre Bône , Marc-Michel Rohé , Pietro Gori , Isabelle Bloch

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Hongjie Zhu , Xiwei Liu , Rundong Xue , Zeyu Zhang , Yong Xu , Daji Ergu , Ying Cai , Yang Zhao

Multiple instance learning (MIL) is the preferred approach for whole slide image classification. However, most MIL approaches do not exploit the interdependencies of tiles extracted from a whole slide image, which could provide valuable…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Marvin Lerousseau , Maria Vakalopoulou , Eric Deutsch , Nikos Paragios

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Ifrat Ikhtear Uddin , Longwei Wang , Xiao Qin , Yang Zhou , KC Santosh

Self-supervised learning (SSL) methods have shown promise for medical imaging applications by learning meaningful visual representations, even when the amount of labeled data is limited. Here, we extend state-of-the-art contrastive learning…

Computational pathology methods have the potential to improve access to precision medicine, as well as the reproducibility and accuracy of pathological diagnoses. Particularly the analysis of whole-slide-images (WSIs) of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Philippe Weitz , Viktoria Sartor , Balazs Acs , Stephanie Robertson , Daniel Budelmann , Johan Hartman , Mattias Rantalainen

To synthesize high-fidelity samples, diffusion models typically require auxiliary data to guide the generation process. However, it is impractical to procure the painstaking patch-level annotation effort required in specialized domains like…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Alexandros Graikos , Srikar Yellapragada , Minh-Quan Le , Saarthak Kapse , Prateek Prasanna , Joel Saltz , Dimitris Samaras

Organoids, sophisticated in vitro models of human tissues, are crucial for medical research due to their ability to simulate organ functions and assess drug responses accurately. Accurate organoid instance segmentation is critical for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Gui Huang , Kangyuan Zheng , Xuan Cai , Jiaqi Wang , Jianjia Zhang , Kaida Ning , Wenbo Wei , Yujuan Zhu , Jiong Zhang , Mengting Liu

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui

Subspace clustering has become widely adopted for the unsupervised analysis of hyperspectral images (HSIs). Recent model-aware deep subspace clustering methods often use a two-stage framework, involving the calculation of a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Nikos Deligiannis , Aleksandra Pižurica

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Place recognition gives a SLAM system the ability to correct cumulative errors. Unlike images that contain rich texture features, point clouds are almost pure geometric information which makes place recognition based on point clouds…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Lin Li , Xin Kong , Xiangrui Zhao , Tianxin Huang , Yong Liu

Semi-supervised learning (SSL) methods, which can leverage a large amount of unlabeled data for improved performance, has attracted increasing attention recently. In this paper, we introduce a novel Context-aware Conditional Cross Pseudo…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Peng Liu , Guoyan Zheng
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