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Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

In the rapidly evolving field of healthcare and beyond, the integration of generative AI in Electronic Health Records (EHRs) represents a pivotal advancement, addressing a critical gap in current information extraction techniques. This…

Computation and Language · Computer Science 2024-06-03 Mohammed-Khalil Ghali , Abdelrahman Farrag , Hajar Sakai , Hicham El Baz , Yu Jin , Sarah Lam

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

We present UniGen-1.5, a unified multimodal large language model (MLLM) for advanced image understanding, generation and editing. Building upon UniGen, we comprehensively enhance the model architecture and training pipeline to strengthen…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Rui Tian , Mingfei Gao , Haiming Gang , Jiasen Lu , Zhe Gan , Yinfei Yang , Zuxuan Wu , Afshin Dehghan

Fine-tuning for large language models (LLMs) typically requires substantial amounts of high-quality supervised data, which is both costly and labor-intensive to acquire. While synthetic data generation has emerged as a promising solution,…

Computation and Language · Computer Science 2025-05-28 Zihong Chen , Wanli Jiang , Jinzhe Li , Zhonghang Yuan , Huanjun Kong , Wanli Ouyang , Nanqing Dong

Training a neural network-based biomedical named entity recognition (BioNER) model usually requires extensive and costly human annotations. While several studies have employed multi-task learning with multiple BioNER datasets to reduce…

Computation and Language · Computer Science 2024-12-31 Yu Yin , Hyunjae Kim , Xiao Xiao , Chih Hsuan Wei , Jaewoo Kang , Zhiyong Lu , Hua Xu , Meng Fang , Qingyu Chen

Large Language Models (LLMs) have demonstrated exceptional capabilities across diverse natural language processing (NLP) tasks. The release of open-source LLMs like LLaMA and Qwen has triggered the development of numerous fine-tuned models…

Computation and Language · Computer Science 2025-06-17 Zichuan Fu , Xian Wu , Yejing Wang , Wanyu Wang , Shanshan Ye , Hongzhi Yin , Yi Chang , Yefeng Zheng , Xiangyu Zhao

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

With Large Language Models (LLMs) recently demonstrating impressive proficiency in code generation, it is promising to extend their abilities to Hardware Description Language (HDL). However, LLMs tend to generate single HDL code blocks…

Machine Learning · Computer Science 2025-10-10 Jinwei Tang , Jiayin Qin , Kiran Thorat , Chen Zhu-Tian , Yu Cao , Yang , Zhao , Caiwen Ding

In the field of Natural Language Processing (NLP), Named Entity Recognition (NER) is recognized as a critical technology, employed across a wide array of applications. Traditional methodologies for annotating datasets for NER models are…

Computation and Language · Computer Science 2025-01-03 Yuji Naraki , Ryosuke Yamaki , Yoshikazu Ikeda , Takafumi Horie , Kotaro Yoshida , Ryotaro Shimizu , Hiroki Naganuma

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large Language Models (LLMs) have recently shown promise in streamlining hardware design processes by encapsulating vast amounts of domain-specific data. In addition, they allow users to interact with the design processes through natural…

Machine Learning · Computer Science 2024-07-04 Yongan Zhang , Zhongzhi Yu , Yonggan Fu , Cheng Wan , Yingyan Celine Lin

Although large language models (LLMs) have advanced the state-of-the-art in NLP significantly, deploying them for downstream applications is still challenging due to cost, responsiveness, control, or concerns around privacy and security. As…

Computation and Language · Computer Science 2023-11-01 Dong-Ho Lee , Jay Pujara , Mohit Sewak , Ryen W. White , Sujay Kumar Jauhar

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Purpose: To develop and evaluate an automated system for extracting structured clinical information from unstructured radiology and pathology reports using open-weights large language models (LMs) and retrieval augmented generation (RAG),…

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Large Language Models (LLMs) have attracted significant attention in recommender systems for their excellent world knowledge capabilities. However, existing methods that rely on Euclidean space struggle to capture the rich hierarchical…

Information Retrieval · Computer Science 2025-04-22 Wentao Cheng , Zhida Qin , Zexue Wu , Pengzhan Zhou , Tianyu Huang