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The rapid progress in Large Language Models (LLMs) could transform many fields, but their fast development creates significant challenges for oversight, ethical creation, and building user trust. This comprehensive review looks at key trust…

Computers and Society · Computer Science 2024-07-22 Md Meftahul Ferdaus , Mahdi Abdelguerfi , Elias Ioup , Kendall N. Niles , Ken Pathak , Steven Sloan

The application of large language models (LLMs) in healthcare holds significant promise for enhancing clinical decision-making, medical research, and patient care. However, their integration into real-world clinical settings raises critical…

Computers and Society · Computer Science 2025-09-18 Manar Aljohani , Jun Hou , Sindhura Kommu , Xuan Wang

Large Language Models (LLMs) are transforming writing, reading, teaching, and knowledge retrieval in many academic fields. However, concerns regarding their misuse and erroneous outputs have led to varying degrees of trust in LLMs within…

Computers and Society · Computer Science 2025-02-10 Minseok Jung , Aurora Zhang , May Fung , Junho Lee , Paul Pu Liang

Applications of Large Language Models (LLMs) are rapidly growing in industry and academia for various software engineering (SE) tasks. As these models become more integral to critical processes, ensuring their reliability and…

Software Engineering · Computer Science 2025-10-07 Dipin Khati , Yijin Liu , David N. Palacio , Yixuan Zhang , Denys Poshyvanyk

Educational technology innovations leveraging large language models (LLMs) have shown the potential to automate the laborious process of generating and analysing textual content. While various innovations have been developed to automate a…

Computation and Language · Computer Science 2023-08-29 Lixiang Yan , Lele Sha , Linxuan Zhao , Yuheng Li , Roberto Martinez-Maldonado , Guanliang Chen , Xinyu Li , Yueqiao Jin , Dragan Gašević

Large Language Models (LLMs) are transforming scholarly tasks like search and summarization, but their reliability remains uncertain. Current evaluation metrics for testing LLM reliability are primarily automated approaches that prioritize…

Human-Computer Interaction · Computer Science 2026-02-25 Anna Martin-Boyle , William Humphreys , Martha Brown , Cara Leckey , Harmanpreet Kaur

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Large Language Models (LLMs) have exploded a new heatwave of AI for their ability to engage end-users in human-level conversations with detailed and articulate answers across many knowledge domains. In response to their fast adoption in…

Large Language Models (LLMs) are increasingly embedded in academic writing practices. Although numerous studies have explored how researchers employ these tools for scientific writing, their concrete implementation, limitations, and design…

Human-Computer Interaction · Computer Science 2025-12-15 Brenda Nogueira , Werner Geyer , Andrew Anderson , Toby Jia-Jun Li , Dongwhi Kim , Nuno Moniz , Nitesh V. Chawla

Ensuring alignment, which refers to making models behave in accordance with human intentions [1,2], has become a critical task before deploying large language models (LLMs) in real-world applications. For instance, OpenAI devoted six months…

Artificial Intelligence · Computer Science 2024-03-22 Yang Liu , Yuanshun Yao , Jean-Francois Ton , Xiaoying Zhang , Ruocheng Guo , Hao Cheng , Yegor Klochkov , Muhammad Faaiz Taufiq , Hang Li

The rapid rise in popularity of Large Language Models (LLMs) with emerging capabilities has spurred public curiosity to evaluate and compare different LLMs, leading many researchers to propose their own LLM benchmarks. Noticing preliminary…

Artificial Intelligence · Computer Science 2025-05-15 Timothy R. McIntosh , Teo Susnjak , Nalin Arachchilage , Tong Liu , Paul Watters , Malka N. Halgamuge

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Large language models (LLMs) have demonstrated transformative potential in scientific research, yet their deployment in high-stakes contexts raises significant trustworthiness concerns. Here, we introduce SciTrust 2.0, a comprehensive…

Artificial Intelligence · Computer Science 2025-10-31 Emily Herron , Junqi Yin , Feiyi Wang

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite their potential benefits, researchers have underscored various ethical implications. While individual instances have…

Computers and Society · Computer Science 2024-07-09 Joschka Haltaufderheide , Robert Ranisch

This paper surveys evaluation techniques to enhance the trustworthiness and understanding of Large Language Models (LLMs). As reliance on LLMs grows, ensuring their reliability, fairness, and transparency is crucial. We explore algorithmic…

Computation and Language · Computer Science 2024-06-05 Nik Bear Brown

Despite the superior capabilities of Multimodal Large Language Models (MLLMs) across diverse tasks, they still face significant trustworthiness challenges. Yet, current literature on the assessment of trustworthy MLLMs remains limited,…

Computation and Language · Computer Science 2024-12-09 Yichi Zhang , Yao Huang , Yitong Sun , Chang Liu , Zhe Zhao , Zhengwei Fang , Yifan Wang , Huanran Chen , Xiao Yang , Xingxing Wei , Hang Su , Yinpeng Dong , Jun Zhu

Large Reasoning Models (LRMs) have emerged as a powerful advancement in multi-step reasoning tasks, offering enhanced transparency and logical consistency through explicit chains of thought (CoT). However, these models introduce novel…

Cryptography and Security · Computer Science 2026-04-15 Jiawei Chen , Yang Yang , Chao Yu , Yu Tian , Zhi Cao , Xue Yang , Linghao Li , Hang Su , Zhaoxia Yin

While the widespread use of Large Language Models (LLMs) brings convenience, it also raises concerns about the credibility of academic research and scholarly processes. To better understand these dynamics, we evaluate the penetration of…

Computation and Language · Computer Science 2025-02-18 Li Zhou , Ruijie Zhang , Xunlian Dai , Daniel Hershcovich , Haizhou Li

The advancement of large language models (LLMs) has outpaced traditional evaluation methodologies. This progress presents novel challenges, such as measuring human-like psychological constructs, moving beyond static and task-specific…

Computation and Language · Computer Science 2026-03-12 Haoran Ye , Jing Jin , Yuhang Xie , Xin Zhang , Guojie Song
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